Professor Emeritus in Medicine-Cardiology, Northwestern University Medical School
Cardiology
Dr. Francis J. Klocke, MD
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Francis Klocke is an expert in the field of Cardiology. He attended University at Buffalo, School of Medicine and Biomedical Sciences. He over the years received 1 awards: "Elected Member". Francis J. Klocke, MD is also a published doctor. He has 99 publication published. The most recent publication is: Contrast magnetic resonance imaging in the assessment of myocardial viability in patients with stable coronary artery disease and left ventricular dysfunction.
Publications
- Resting versus vasodilated pressure gradients in assessing stenosis severity.
- Probing transmural myocardial perfusion with CMR.
- Absolute myocardial blood flow emerging role in coronary pathophysiology and clinical disease.
- Epicardial coronary artery vasomotion.
- Cardiac magnetic resonance measurements of area at risk and infarct size in ischemic syndromes.
- Ranolazine and the myocardial demand-supply balance.
- Emerging applications of T2-weighted cardiac magnetic resonance imaging in acute ischemic syndromes.
- "Shades of gray" in cardiac magnetic resonance images of infarcted myocardium: can they tell us what we'd like them to?
- Contrast-enhanced cardiac magnetic resonance in the evaluation of myocardial infarction and myocardial viability in patients with ischemic heart disease.
- Magnetic resonance approaches and recent advances in myocardial perfusion imaging.
- Resting blood flow in hypocontractile myocardium: resolving the controversy.
- Myosin-binding protein C phosphorylation, myofibril structure, and contractile function during low-flow ischemia.
- Magnetic resonance versus radionuclide pharmacological stress perfusion imaging for flow-limiting stenoses of varying severity.
- Infarct resorption, compensatory hypertrophy, and differing patterns of ventricular remodeling following myocardial infarctions of varying size.
- Cardiac magnetic resonance imaging: what can it add clinically in 2004?
- Gadolinium cardiovascular magnetic resonance predicts reversible myocardial dysfunction and remodeling in patients with heart failure undergoing beta-blocker therapy.
- Testing coronary flow reserve without a provocative stress. A "BOLD" approach.
- Myocardial scarring in asymptomatic or mildly symptomatic patients with hypertrophic cardiomyopathy.
- HSC73-tubulin complex formation during low-flow ischemia in the canine myocardium.
- Limits of detection of regional differences in vasodilated flow in viable myocardium by first-pass magnetic resonance perfusion imaging.
- Contrast-enhanced coronary MR angiography: relationship between coronary artery delineation and blood T1.
- Assessment of regional differences in myocardial blood flow using T2-weighted 3D BOLD imaging.
- Visualization of discrete microinfarction after percutaneous coronary intervention associated with mild creatine kinase-MB elevation.
- Visualisation of presence, location, and transmural extent of healed Q-wave and non-Q-wave myocardial infarction.
- Contrast-enhanced magnetic resonance imaging of myocardium at risk: distinction between reversible and irreversible injury throughout infarct healing.
- The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction.
- The role of the American College of Cardiology in promoting and maintaining the delivery of quality cardiovascular care in the future.
- Myofibrillar disruption in hypocontractile myocardium showing perfusion-contraction matches and mismatches.
- Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function.
- Caspase inhibition reduces myocyte cell death induced by myocardial ischemia and reperfusion in vivo.
- Contrast magnetic resonance imaging in the assessment of myocardial viability in patients with stable coronary artery disease and left ventricular dysfunction.
- Coronary vascular responsiveness to adenosine is impaired additively by blockade of nitric oxide synthesis and a sulfonylurea.
- Proportionate reversible decreases in systolic function and myocardial oxygen consumption after modest reductions in coronary flow: hibernation versus stunning.
- Fast 23Na magnetic resonance imaging of acute reperfused myocardial infarction. Potential to assess myocardial viability.
- Blockade of nitric oxide synthesis reduces myocardial oxygen consumption in vivo.
- Endothelium-derived relaxing factor (nitric oxide) has a tonic vasodilating action on coronary collateral vessels.
- Tone-dependent coronary arterial-venous pressure differences at the cessation of venous outflow during long diastoles.
- Clinical competence in elective direct current (DC) cardioversion. A statement for physicians from the AHA/ACC/ACP Task Force on Clinical Privileges in Cardiology.
- Clinical competence in ambulatory electrocardiography. A statement for physicians from the AHA/ACC/ACP Task Force on Clinical Privileges in Cardiology.
- Clinical competence in invasive cardiac electrophysiological studies. A statement for physicians from the ACP/ACC/AHA Task Force on Clinical Privileges in Cardiology.
- Clinical competence in insertion of a temporary transvenous ventricular pacemaker. A statement for physicians from the ACP/ACC/AHA Task Force on Clinical Privileges in...
- 26th Bethesda conference: recommendations for determining eligibility for competition in athletes with cardiovascular abnormalities. Task Force 5: coronary artery dise...
- Rapid radioimmunoassay for serum myoglobin.
- Measurement of heterogeneous myocardial blood flow.
- Inert gas measurements of myocardial perfusion in the presence of heterogeneous flow documented by microspheres.
- Sympathetic influences on coronary perfusion and evolving concepts of driving pressure, resistance, and transmural flow regulation.
- Effects of preload on the transmural distribution of perfusion and pressure-flow relationships in the canine coronary vascular bed.
- Curvilinearity of the diastolic pressure-flow relationship in autoregulating and maximally vasodilated coronary beds; effects on estimates of zero-flow pressure and di...
- Zero-flow pressures and pressure-flow relationships during single long diastoles in the canine coronary bed before and during maximum vasodilation. Limited influence o...
- Reduced coronary flow in a canine model of "muscle bridge" with inflow occlusion extending into diastole; possible role of downstream vascular closure.
- Rapid renal clearance of immunoreactive canine plasma myoglobin.
- Control of coronary blood flow.
- Measurements of coronary blood flow and degree of stenosis: current clinical implications and continuing uncertainties.
- Effects of hyperventilation on pulmonary blood flow and recirculation time of humans.
- Preload-induced alterations in capacitance-free diastolic pressure-flow relationship.
- Reductions in coronary flow under resting conditions in collateral-dependent myocardium of patients with complete occlusion of the left anterior descending coronary ar...
- Studies on digitalis. 13. A comparison of the effects of potassium on the inotropic and arrhythmia-producing actions of ouabain.
- Mechanism of increase of myocardial oxygen uptake produced by catecholamines.
- Effects of heterogeneous myocardial perfusion on coronary venous H2 desaturation curves and calculations of coronary flow.
- Heterogeneity of coronary blood flow in human coronary artery disease and experimental myocardial infarction.
- Relationship of heart rate to ventricular automaticity in dogs during ouabain administration.
- Evaluation of venous bypass grafts from aorta to coronary artery by inert gas desaturation and direct flowmeter techniques.
- Oxygen cost of electrical activation of the heart.
- Measurement of cardiac output in man with a nonrecirculating indicator.
- Inert gas measurements of coronary blood flow.
- Right atrial admixture in coronary venous blood.
- Indicator-dilution measurement of cardiac output with dissolved hydrogen.
- Relationship of stimulation frequency to automaticity in the canine Purkinje fiber during ouabain administration.
- Average coronary blood flow per unit weight of left ventricle in patients with and without coronary artery disease.
- Acceleration of ventricular pacemakers by transient increases in heart rate in dogs during ouabain administration.
- Patterns of myoglobin release after reperfusion of injured myocardium.
- Pressure and tone dependence of coronary diastolic input impedance and capacitance.
- Coronary pressure-flow relationships. Controversial issues and probable implications.
- Reduced regional myocardial perfusion in the presence of pharmacologic vasodilator reserve.
- Adjustments in regional coronary perfusion accompanying reductions in regional coronary arterial pressure.
- Reductions in regional myocardial function at rest in conscious dogs with chronically reduced regional coronary artery pressure.
- Characterization of capacitance-free pressure-flow relations during single diastoles in dogs using an RC model with pressure-dependent parameters.
- Interpretation of changes in coronary flow that accompany pharmacologic interventions.
- Major demographic and epidemiologic trends affecting adult cardiology.
- Physicians as advocates in the 1980s and 1990s.
- Coronary capacitance.
- Early noninvasive detection of successful reperfusion in patients with acute myocardial infarction.
- Measurements of coronary flow reserve: defining pathophysiology versus making decisions about patient care.
- Effects of graded reductions in coronary perfusion pressure on the diastolic pressure-segment length relation and the rate of isovolumic relaxation in the resting cons...
- Ethics in cardiovascular medicine. Task Force I: Background and general principles.
- Clinical competence in percutaneous transluminal coronary angioplasty. A statement for physicians from the ACP/ACC/AHA Task Force on Clinical Privileges in Cardiology.
- Cognition in the era of technology: "seeing the shades of gray".
- ACC/AHA guidelines for the early management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Tas...
- Tone-dependent waterfall behavior during venous pressure elevation in isolated canine hearts.
- ACC/AHA guidelines for cardiac catheterization and cardiac catheterization laboratories. American College of Cardiology/American Heart Association Ad Hoc Task Force on...
- Dissociation of diastolic pressure-segment length and pressure-wall thickness relations during vasodilation in the conscious dog.
- First-pass entry of nonionic contrast agent into the myocardial extravascular space. Effects on radiographic estimates of transit time and blood volume.
- Exercise and atherosclerotic heart disease in women.
- Origin of great cardiac vein and coronary sinus drainage within the left ventricle.
- Quantitative evaluation of coronary perfusion in man.
- An efficient optimization technique for recovering ventilation-perfusion distributions from inert gas data. Effects of random experimental error.
- Measurement of cardiac output using improved chromatographic analysis of sulfur hexafluoride (SF6).
- Coronary blood flow in man.
Schools
University At Buffalo State University Of New York School Of Medicine
Yale New Haven Med Center
National Heart Institute
Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- Elected Member
Education
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National Institutes of Health Clinical Center -
Yale-New Haven Hospital -
University at Buffalo, School of Medicine and Biomedical Sciences
Hospital
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Northwestern Memorial Hospital
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