Professor, Laboratory Medicine, University of Washington School of Medicine

Infectious Disease

Ferric C. Fang, MD practices Infectious Disease. He went to medical school at Harvard Medical School. Harvard Medical School is a top medical college. Harvard Medical School is ranked 1 in research and 12 in primary care medicine He received 1 awards: "Elected Member". Ferric Fang is also a published MD. He has 99 paper published. The most recent paper is: Correction for Fang and Casadevall, Competitive Science: Is Competition Ruining Science?

Publications

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• Fluoroquinolone Resistance in Salmonella and the Utility of Perfloxacin Disk Diffusion.
• Correction for Fang and Casadevall, Competitive Science: Is Competition Ruining Science?
• Human Diphyllobothrium nihonkaiense Infection in Washington State.
• Competitive science: is competition ruining science?
• Reply to Agger and Kowalski.
• Pain and Bloody Ear Discharge in a Returning Traveler.
• Manganese superoxide dismutase deficiency triggers mitochondrial uncoupling and the Warburg effect.
• Integrated circuits: how transcriptional silencing and counter-silencing facilitate bacterial evolution.
• The Ins and Outs of Bacterial Iron Metabolism.
• Sources of error in the retracted scientific literature.
• Reflexive Culture in Adolescents and Adults with Group A Streptococcal Pharyngitis.
• Evaluation of Three Rapid Diagnostic Methods to Directly Identify Microorganisms from Positive Blood Cultures.
• Distinct Roles of the Salmonella enterica Serovar Typhimurium CyaY and YggX Proteins in the Biosynthesis and Repair of Iron-Sulfur Clusters.
• SPECIALIZED SCIENCE.
• Predictive Diagnostics for Escherichia coli Infections Based on the Clonal Association of Antimicrobial Resistance and Clinical Outcome.
• Is the Nobel Prize good for science?
• Probiotic bacteria reduce salmonella typhimurium intestinal colonization by competing for iron.
• Iron and citrate export by a major facilitator superfamily pump regulates metabolism and stress resistance in Salmonella Typhimurium.
• Abrupt Emergence of a Single Dominant Multidrug-Resistant Strain of Escherichia coli.
• Salmonella enterica Causes More Severe Inflammatory Disease in C57/BL6 Nramp1G169 Mice Than Sv129S6 Mice.
• Males Are Overrepresented among Life Science Researchers Committing Scientific Misconduct.
• Virulence and stress-related periplasmic protein (VisP) in bacterial/host associations.
• A tollgate for typhoid.
• Misconduct accounts for the majority of retracted scientific publications.
• The NsrR regulon in nitrosative stress resistance of Salmonella enterica serovar Typhimurium.
• Evolution of Salmonella enterica Virulence via Point Mutations in the Fimbrial Adhesin.
• Real-Time Quantitative Reverse Transcription PCR for Monitoring of Blood-Stage Plasmodium falciparum Infections in Malaria Human Challenge Trials.
• REFORMING SCIENCE I. METHODOLOGICAL AND CULTURAL REFORMS.
• REFORMING SCIENCE II. STRUCTURAL REFORMS.
• Nifedipine Affects the Course of Salmonella enterica Serovar Typhimurium Infection by Modulating Macrophage Iron Homeostasis.
• RETRACTED SCIENCE AND THE RETRACTION INDEX.
• Multiple Targets of Nitric Oxide in the Tricarboxylic Acid Cycle of Salmonella enterica Serovar Typhimurium.
• Microbial virulence as an emergent property: consequences and opportunities.
• The Moraxella catarrhalis nitric oxide reductase is essential for nitric oxide detoxification.
• Integrated stress responses in Salmonella.
• Reductionistic and holistic science.
• Antimicrobial actions of reactive oxygen species.
• What is the current role of algorithmic approaches for diagnosis of Clostridium difficile infection?
• Reproducible science.
• Ureaplasma urealyticum continuous ambulatory peritoneal dialysis-associated peritonitis diagnosed by 16S rRNA gene PCR.
• Impact of strain type on detection of toxigenic Clostridium difficile: comparison of molecular diagnostic and enzyme immunoassay approaches.
• Humanized nonobese diabetic-scid IL2rgammanull mice are susceptible to lethal Salmonella Typhi infection.
• PoxA, yjeK, and elongation factor P coordinately modulate virulence and drug resistance in Salmonella enterica.
• Taming the elephant: Salmonella biology, pathogenesis, and prevention.
• Lost in translation--basic science in the era of translational research.
• Regulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threonine kinase and phosphatase.
• Evaluation of tcdB real-time PCR in a three-step diagnostic algorithm for detection of toxigenic Clostridium difficile.
• Nutrient availability as a mechanism for selection of antibiotic tolerant Pseudomonas aeruginosa within the CF airway.
• Absence of functional Hfe protects mice from invasive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2.
• Important science--it's all about the SPIN.
• Mechanistic science.
• The Base Excision Repair system of Salmonella enterica serovar typhimurium counteracts DNA damage by host nitric oxide.
• Is peer review censorship?
• NIH peer review reform--change we need, or lipstick on a pig?
• Population variability of the FimH type 1 fimbrial adhesin in Klebsiella pneumoniae.
• Identification of a repressor of a truncated denitrification pathway in Moraxella catarrhalis.
• The CorA Mg2+ channel is required for the virulence of Salmonella enterica serovar typhimurium.
• Descriptive science.
• Regulatory and structural differences in the Cu,Zn-superoxide dismutases of Salmonella enterica and their significance for virulence.
• On rejection.
• A nitric oxide-inducible lactate dehydrogenase enables Staphylococcus aureus to resist innate immunity.
• Coordinate regulation of Salmonella pathogenicity island 1 (SPI1) and SPI4 in Salmonella enterica serovar Typhimurium.
• Analysis of nitric oxide-dependent antimicrobial actions in macrophages and mice.
• Silencing of xenogeneic DNA by H-NS-facilitation of lateral gene transfer in bacteria by a defense system that recognizes foreign DNA.
• Man is not a mouse: reply.
• Maintenance of nitric oxide and redox homeostasis by the salmonella flavohemoglobin hmp.
• Selective silencing of foreign DNA with low GC content by the H-NS protein in Salmonella.
• Suppressor alphabeta T lymphocytes control innate resistance to endotoxic shock.
• Characterization of six lipoproteins in the sigmaE regulon.
• Sigma cascades in prokaryotic regulatory networks.
• Isocitrate lyase (AceA) is required for Salmonella persistence but not for acute lethal infection in mice.
• Comparison of the PhoPQ regulon in Escherichia coli and Salmonella typhimurium.
• Liver abscess caused by magA+ Klebsiella pneumoniae in North America.
• Clinical isolates of Staphylococcus intermedius masquerading as methicillin-resistant Staphylococcus aureus.
• The Salmonella enterica serovar typhimurium divalent cation transport systems MntH and SitABCD are essential for virulence in an Nramp1G169 murine typhoid model.
• Isolation of metronidazole-resistant Bacteroides fragilis carrying the nimA nitroreductase gene from a patient in Washington State.
• Toll-like receptor 4 dependence of innate and adaptive immunity to Salmonella: importance of the Kupffer cell network.
• The ferritin-like Dps protein is required for Salmonella enterica serovar Typhimurium oxidative stress resistance and virulence.
• Inhibition of bacterial DNA replication by zinc mobilization during nitrosative stress.
• Nitric oxide production by human macrophages: there's NO doubt about it.
• The global regulator ArcA controls resistance to reactive nitrogen and oxygen intermediates in Salmonella enterica serovar Enteritidis.
• Host specificity of bacterial pathogens.
• Why has the number of scientific retractions increased?
• Slc11a1 limits intracellular growth of Salmonella enterica sv. Typhimurium by promoting macrophage immune effector functions and impairing bacterial iron acquisition.
• The phage shock protein PspA facilitates divalent metal transport and is required for virulence of Salmonella enterica sv. Typhimurium.
• Reply to "likelihood of false-positive results in high-impact journals publishing groundbreaking research".
• Vaccination with attenuated Salmonella enterica Dublin expressing E coli O157:H7 outer membrane protein Intimin induces transient reduction of fecal shedding of E coli...
• Acid stress activation of the sigma(E) stress response in Salmonella enterica serovar Typhimurium.
• New insights into transcriptional regulation by H-NS.
• Biosynthesis and IroC-dependent export of the siderophore salmochelin are essential for virulence of Salmonella enterica serovar Typhimurium.
• The response regulator SsrB activates expression of diverse Salmonella pathogenicity island 2 promoters and counters silencing by the nucleoid-associated protein H-NS.
• The role of ferritins in the physiology of Salmonella enterica sv. Typhimurium: a unique role for ferritin B in iron-sulphur cluster repair and virulence.
• Regulation of Salmonella typhimurium virulence gene expression by cationic antimicrobial peptides.
• The nitrosative stress response of Staphylococcus aureus is required for resistance to innate immunity.
• Antimicrobial reactive oxygen and nitrogen species: concepts and controversies.
• Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ.
• The alternative sigma factor sigma is required for resistance of Salmonella enterica serovar Typhimurium to anti-microbial peptides.
• Alternative sigma factor interactions in Salmonella: sigma and sigma promote antioxidant defences by enhancing sigma levels.

Schools

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• Harvard Medical School

• Ucsd Med Center

Doctors Specialties

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• Infectious Disease Medicine
• Infectious Disease

Accepted Insurances

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Awards

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• Elected Member

Education

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• Harvard Medical School

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