Professor of Pediatrics, University Colorado
Pediatrics
Dr. Erwin W. Gelfand, MD
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Dr. Erwin W. Gelfand works in the field of Pediatrics. He has 3 awards "America's Top Doctors", "CORE Magazine" and "Elected Member". Erwin Gelfand is also a published physician. He has 99 paper published. The most recent paper is: Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection.
Publications
- Primary Immunodeficiency Masquerading as Allergic Disease.
- Common Variable Immunodeficiency: Diagnosis, Management, and Treatment.
- Late Onset Hypomorphic RAG2 Deficiency Presentation with Fatal Vaccine-Strain VZV Infection.
- Successful hematopoietic cell transplantation in patients with unique NF-κB essential modulator (NEMO) mutations.
- JNK2 Regulates the Functional Plasticity of Naturally Occurring T Regulatory Cells and the Enhancement of Lung Allergic Responses.
- Is There a Link Between Obesity and Asthma?
- Leukotriene B4 receptor 1 is differentially expressed on peripheral T cells of steroid-sensitive and -resistant asthmatics.
- Effects of Anti-G and Anti-F Antibodies on Airway Function Following Respiratory Syncytial Virus Infection.
- Targeting Pim1 kinase in the treatment of peanut allergy.
- The Effects of Airway Microbiome on Corticosteroid Responsiveness in Asthma.
- Steroidogenic enzyme Cyp11a1 regulates Type 2 CD8+ T cell skewing in allergic lung disease.
- IL-13-producing BLT1-positive CD8 cells are increased in asthma and are associated with airway obstruction.
- Controversies in IgG replacement therapy in patients with antibody deficiency diseases.
- Stepwise Epigenetic and Phenotypic Alterations Poise CD8+ T Cells To Mediate Airway Hyperresponsiveness and Inflammation.
- Sequential engagement of Fc?RI on Mast Cells and Basophil Histamine H(4) Receptor and Fc?RI in Allergic Rhinitis.
- Intravenous immune globulin in autoimmune and inflammatory diseases.
- Responsiveness to respiratory syncytial virus in neonates is mediated through thymic stromal lymphopoietin and OX40 ligand.
- Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing T(H)2 and T(H)17 T-cell differentiation.
- Development of asthma is determined by the age-dependent host response to respiratory virus infection: therapeutic implications.
- Loss of T Regulatory Cell Suppression following Signaling through Glucocorticoid-induced Tumor Necrosis Receptor (GITR) Is Dependent on c-Jun N-terminal Kinase Activat...
- ERK1 is important for Th2 differentiation and development of experimental asthma.
- Successful treatment of eosinophilic esophagitis with ciclesonide.
- The Critical Role of Complement Alternative Pathway Regulator Factor H in Allergen-Induced Airway Hyperresponsiveness and Inflammation.
- Inhibition of Pim1 Kinase Activation Attenuates Allergen-Induced Airway Hyperresponsiveness and Inflammation.
- Low-Dose Lipopolysaccharide Affects Lung Allergic Responses by Regulating Jagged1 Expression on Antigen-Pulsed Dendritic Cells.
- The Response of Children with Asthma to Ambient Particulate is Modified by Tobacco Smoke Exposure.
- Urinary leukotriene E(4) levels identify children with tobacco smoke exposure at risk for asthma exacerbation.
- Targeting CXCR3 reduces ligand-induced T-Cell activation but not development of lung allergic responses.
- Requirement for CCR5 in the Development of Allergen-Induced Airway Hyperresponsiveness and Inflammation.
- Reduced thymic output, cell cycle abnormalities, and increased apoptosis of T lymphocytes in patients with cartilage-hair hypoplasia.
- Blocking the Leukotriene B4 Receptor 1 Inhibits Late Phase Airway Responses in Established Disease.
- SLAP deficiency enhances number and function of regulatory T cells preventing chronic autoimmune arthritis in SKG mice.
- CD8 regulates T regulatory cell production of IL-6 and maintains their suppressive phenotype in allergic lung disease.
- Montelukast during primary infection prevents airway hyperresponsiveness and inflammation after reinfection with respiratory syncytial virus.
- A randomized trial to test the effectiveness of art therapy for children with asthma.
- Peanut-induced intestinal allergy is mediated through a mast cell-IgE-FcepsilonRI-IL-13 pathway.
- Plasticity of invariant NKT cell regulation of allergic airway disease is dependent on IFN-gamma production.
- The importance and features of the distal airways in children and adults.
- Differential effects of dendritic cell transfer on airway hyperresponsiveness and inflammation.
- Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production.
- Antigen specificity is not required for modulation of lung allergic responses by naturally occurring regulatory T cells.
- Vaccine-induced CD8+ T cell-dependent suppression of airway hyperresponsiveness and inflammation.
- Leukotriene B4 release from mast cells in IgE-mediated airway hyperresponsiveness and inflammation.
- Effect of the inhaled corticosteroid mometasone on small airway patency in patients with asthma.
- Pediatric asthma: a different disease.
- Vgamma1+ T cells and tumor necrosis factor-alpha in ozone-induced airway hyperresponsiveness.
- Allergic airway hyperresponsiveness-enhancing gammadelta T cells develop in normal untreated mice and fail to produce IL-4/13, unlike Th2 and NKT cells.
- Virus-specific IgE enhances airway responsiveness on reinfection with respiratory syncytial virus in newborn mice.
- Mitogen-activated protein kinase/extracellular signal-regulated kinase 1/2-dependent pathways are essential for CD8+ T cell-mediated airway hyperresponsiveness and inf...
- The Atopic Dermatitis Quickscore (ADQ): validation of a new parent-administered atopic dermatitis scoring tool.
- Leukotriene B4 receptor 1 expression on dendritic cells is required for the development of Th2 responses and allergen-induced airway hyperresponsiveness.
- Evidence that CD8+ dendritic cells enable the development of gammadelta T cells that modulate airway hyperresponsiveness.
- A novel mutation in NFKBIA/IKBA results in a degradation-resistant N-truncated protein and is associated with ectodermal dysplasia with immunodeficiency.
- Exposure to tobacco smoke increases leukotriene E4-related albuterol usage and response to montelukast.
- Plasticity of regulatory T cells: subversion of suppressive function and conversion to enhancement of lung allergic responses.
- Essential role of Notch signaling in effector memory CD8+ T cell-mediated airway hyperresponsiveness and inflammation.
- Estrogen determines sex differences in airway responsiveness after allergen exposure.
- IKBKG (nuclear factor-kappa B essential modulator) mutation can be associated with opportunistic infection without impairing Toll-like receptor function.
- Corticosteroids enhance CD8+ T cell-mediated airway hyperresponsiveness and allergic inflammation by upregulating leukotriene B4 receptor 1.
- Contribution of allergen-specific and nonspecific nasal responses to early-phase and late-phase nasal responses.
- Is asthma in childhood different from asthma in adults? Why do we need special approaches to asthma in children?
- IFN-gamma production during initial infection determines the outcome of reinfection with respiratory syncytial virus.
- Effect of chemically modified IL-13 short interfering RNA on development of airway hyperresponsiveness in mice.
- Advances in therapy for adult asthma.
- Animal models of airway sensitization.
- Activation of naturally occurring lung CD4(+)CD25(+) regulatory T cells requires CD8 and MHC I interaction.
- Airway hyperresponsiveness through synergy of gammadelta} T cells and NKT cells.
- CD8+ T cell-mediated airway hyperresponsiveness and inflammation is dependent on CD4+IL-4+ T cells.
- Arhgef1 is required by T cells for the development of airway hyperreactivity and inflammation.
- A novel mutation of intron 22 in Janus kinase 3-deficient severe combined immunodeficiency.
- IL-10-treated dendritic cells decrease airway hyperresponsiveness and airway inflammation in mice.
- IL-2 and IL-18 attenuation of airway hyperresponsiveness requires STAT4, IFN-gamma, and natural killer cells.
- Naturally occurring lung CD4(+)CD25(+) T cell regulation of airway allergic responses depends on IL-10 induction of TGF-beta.
- Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice.
- Critical role of the Fc receptor gamma-chain on APCs in the development of allergen-induced airway hyperresponsiveness and inflammation.
- IL-13 is essential to the late-phase response in allergic rhinitis.
- Use of the health plan employer data and information set for measuring and improving the quality of asthma care.
- Urine leukotriene E4 levels are associated with decreased pulmonary function in children with persistent airway obstruction.
- Pirfenidone modulates airway responsiveness, inflammation, and remodeling after repeated challenge.
- RANTES (CCL5) regulates airway responsiveness after repeated allergen challenge.
- Factor B of the alternative complement pathway regulates development of airway hyperresponsiveness and inflammation.
- Particulate levels are associated with early asthma worsening in children with persistent disease.
- Syk activation in dendritic cells is essential for airway hyperresponsiveness and inflammation.
- Effect of montelukast on peripheral airflow obstruction in children with asthma.
- CD8+ T lymphocytes and leukotriene B4: novel interactions in the persistence and progression of asthma.
- Once-daily ciclesonide in children: efficacy and safety in asthma.
- The leukotriene B4 receptor (BLT1) is required for effector CD8+ T cell-mediated, mast cell-dependent airway hyperresponsiveness.
- A focus on the asthma HEDIS measure and its implications for clinical practice.
- Inhibition of spleen tyrosine kinase prevents mast cell activation and airway hyperresponsiveness.
- Importance of myeloid dendritic cells in persistent airway disease after repeated allergen exposure.
- Estimating effects of ambient PM(2.5) exposure on health using PM(2.5) component measurements and regression calibration.
- Virus-induced airway dysfunction: pathogenesis and biomechanisms.
- Importance of the personal endotoxin cloud in school-age children with asthma.
- Physiologic assessment of allergic rhinitis in mice: role of the high-affinity IgE receptor (FcepsilonRI).
- Critical decisions in selecting an intravenous immunoglobulin product.
- Protein kinase C alpha, betaI, and betaII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways.
- Distribution and leukocyte contacts of gammadelta T cells in the lung.
- Quantitative computed tomography detects peripheral airway disease in asthmatic children.
Schools
McGill University Faculty Of Medicine
Montreal General Hospital
Montreal Chldns Hospital
Doctors Specialties
- Pediatrics
Accepted Insurances
Awards
- America's Top Doctors
- CORE Magazine
- Elected Member
Education
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Boston Children's Hospital -
McGill University Faculty of Medicine
Hospital
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National Jewish Health
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