Professor, Medicine, UCLA School of Medicine
Family Medicine
Dr. Eric P. Brass, MD
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Eric Brass works in the field of Family Medicine. He researched medicine at Case Western Reserve University School of Medicine. He over the years received 1 awards: "Whos Who in Medicine and Healthcare". Eric Brass is also a published MD. He has 102 publication published. The most recent publication is: Skeletal muscle mitochondrial DNA injury in patients with unilateral peripheral arterial disease.
Publications
- Mitochondria as targets of drug toxicity: Lessons from the R118 phase I experience.
- Structured Frameworks to Increase the Transparency of the Assessment of Benefits and Risks of Medicines: Current Status and Possible Future Directions.
- The treadmill is a better functional test than the 6-minute walk test in therapeutic trials of patients with peripheral artery disease.
- Patient and Hospital-Level Characteristics Associated with the Use of Do-Not-Resuscitate Orders in Patients Hospitalized for Sepsis.
- Resident's morning report: An opportunity to reinforce principles of biomedical science in a clinical context.
- Intermittent claudication: new targets for drug development.
- Assessing the Benefit-Risk for New Drugs: Are the FDA's Endocrinologic and Metabolic Drugs Advisory Committee and the Division of Metabolism and Endocrinology Products...
- Association of clinical attributes and treadmill walking performance in patients with claudication due to peripheral artery disease.
- A Decision-Analysis Tool for Benefit-Risk Assessment of Nonprescription Drugs.
- A systematic review and meta-analysis of propionyl-L-carnitine effects on exercise performance in patients with claudication.
- Risk factors for mortality in patients with mucormycosis.
- A phase II dose-ranging study of the phosphodiesterase inhibitor K-134 in patients with peripheral artery disease and claudication.
- The Deferasirox-AmBisome Therapy for Mucormycosis (DEFEAT Mucor) study: a randomized, double-blinded, placebo-controlled trial.
- Improving the FDA's Advisory Committee Process.
- The Influence of Need for Cognition and Principal Display Panel Factors on Over-the-Counter Drug Facts Label Comprehension.
- Application of Adaptive Design and Decision Making to a Phase II Trial of a Phosphodiesterase Inhibitor for the Treatment of Intermittent Claudication.
- Effect of propionyl-L-carnitine on a background of monitored exercise in patients with claudication secondary to peripheral artery disease.
- Considerations in the development of drugs to treat sarcopenia.
- Design of clinical trials of antibacterial agents for community-acquired bacterial pneumonia.
- Should the guidelines for management of central venous catheters in patients with candidemia be changed now?
- Basic biomedical sciences and the future of medical education: implications for internal medicine.
- Temporal pattern of skeletal muscle gene expression following endurance exercise in Alaskan sled dogs.
- Sixty years of Pharmacological Reviews: has the role of review articles in biomedical sciences changed and, if so, how does this affect Pharmacological Reviews?
- Can consumers self-select for appropriate use of an over-the-counter statin? The Self Evaluation of Lovastatin to Enhance Cholesterol Treatment Study.
- Long-term safety of cilostazol in patients with peripheral artery disease: the CASTLE study (Cilostazol: A Study in Long-term Effects).
- American and German students' knowledge, perceptions, and behaviors with respect to over-the-counter pain relievers.
- The novel phosphodiesterase inhibitor NM-702 improves claudication-limited exercise performance in patients with peripheral arterial disease.
- Potential impact on cardiovascular public health of over-the-counter statin availability.
- Risk assessment in drug development for symptomatic indications: a framework for the prospective exclusion of unacceptable cardiovascular risk.
- Consumer behavior in the setting of over-the-counter statin availability: lessons from the consumer use study of OTC Mevacor.
- Carnitine replacement in end-stage renal disease and hemodialysis.
- Carnitine and sports medicine: use or abuse?
- Impaired muscle oxygen use at onset of exercise in peripheral arterial disease.
- Pulmonary VO2 dynamics during treadmill and arm exercise in peripheral arterial disease.
- Implications of a switch from prescription to over-the-counter status for allergy drugs.
- Trends in antimicrobial drug development: implications for the future.
- Exercise capacity as a predictor of survival among ambulatory patients with end-stage renal disease.
- Label development and the label comprehension study for over-the-counter drugs.
- Premature termination of clinical trials.
- Impact on carnitine homeostasis of short-term treatment with the pivalate prodrug cefditoren pivoxil.
- Pivalate-generating prodrugs and carnitine homeostasis in man.
- Synthetic peptides that exert antimicrobial activities in whole blood and blood-derived matrices.
- Clinical and demographic predictors of exercise capacity in end-stage renal disease.
- Stimulation of Lipogenesis by Interleukin-6 and Misoprostol-Free Acid in Isolated Rat Hepatocytes.
- mtDNA disease in the primary care setting.
- Changing the status of drugs from prescription to over-the-counter availability.
- Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon.
- Intravenous L-carnitine increases plasma carnitine, reduces fatigue, and may preserve exercise capacity in hemodialysis patients.
- Multiple skeletal muscle mitochondrial DNA deletions in patients with unilateral peripheral arterial disease.
- Decreased NADH dehydrogenase and ubiquinol-cytochrome c oxidoreductase in peripheral arterial disease.
- Supplemental carnitine and exercise.
- Decreased carnitine biosynthesis in rats with secondary biliary cirrhosis.
- Acquired skeletal muscle metabolic myopathy in atherosclerotic peripheral arterial disease.
- Oxygen uptake kinetics during exercise are slowed in patients with peripheral arterial disease.
- Relationships between muscle mitochondrial DNA content, mitochondrial enzyme activity and oxidative capacity in man: alterations with disease.
- Rational approach to therapeutic drug monitoring.
- Skeletal muscle mitochondrial DNA injury in patients with unilateral peripheral arterial disease.
- The role of carnitine and carnitine supplementation during exercise in man and in individuals with special needs.
- Skeletal muscle metabolism as a target for drug therapy in peripheral arterial disease.
- Clinical characterization of thrombotic microangiopathy in HIV infection.
- Metabolic profiles of cat and rat pharyngeal and diaphragm muscles.
- Effect of exercise training on skeletal muscle histology and metabolism in peripheral arterial disease.
- Effect of the ACE inhibitor ceronapril on cerebral blood flow in hypertensive patients.
- Quantification of carnitine, acetylcarnitine, and total carnitine in tissues by high-performance liquid chromatography: the effect of exercise on carnitine homeostasis...
- Encephalopathy associated with bismuth subgallate therapy.
- Chronic changes in skeletal muscle histology and function in peripheral arterial disease.
- Inhibition of glucagon-stimulated glycogenolysis by S-nitroso-N-acetylpenicillamine.
- Inositol glycan phosphate derived from human erythrocyte acetylcholinesterase glycolipid anchor and inositol cyclic 1,2-phosphate antagonize glucagon activation of gly...
- Hepatic toxicity of antirheumatic drugs.
- Carnitine delays rat skeletal muscle fatigue in vitro.
- Hydroxycobalamin[c-lactam] increases total coenzyme A content in primary culture hepatocytes by accelerating coenzyme A biosynthesis secondary to Acyl-CoA accumulation.
- Carnitine metabolism during exercise.
- Overview of coenzyme A metabolism and its role in cellular toxicity.
- The American Board of Clinical Pharmacology, Inc., and academic clinical pharmacology: is there a down side?
- Interleukin-6, but not tumour necrosis factor-alpha, increases lipogenesis in rat hepatocyte primary cultures.
- Effect of intravenous L-carnitine on carnitine homeostasis and fuel metabolism during exercise in humans.
- Dose-ranging study of a new, once-daily diltiazem formulation for patients with stable angina.
- Effects of the cholinomimetic SDZ ENS-163 on scopolamine-induced cognitive impairment in humans.
- Dietary substitution of medium chain triglycerides in subjects with non-insulin-dependent diabetes mellitus in an ambulatory setting: impact on glycemic control and in...
- Clinical trials for claudication. Assessment of exercise performance, functional status, and clinical end points. Vascular Clinical Trialists.
- Acetylcholinesterase inhibition by zifrosilone: pharmacokinetics and pharmacodynamics.
- Pharmacokinetic considerations for the therapeutic use of carnitine in hemodialysis patients.
- Hepatic cobalamin deficiency induced by hydroxycobalamin[c-lactam] treatment in rats is associated with decreased mitochondrial mRNA contents and accumulation of polyc...
- Relationship between acid-soluble carnitine and coenzyme A pools in vivo.
- Effect of carnitine on mitochondrial oxidation of palmitoylearnitine.
- In vivo studies of carnitine and fatty acid metabolism: problems with use of anesthetics.
- Pasteurella ureae meningitis associated with endocarditis. Report of a case and review of the literature.
- Drug-induced electrolyte abnormalities.
- Kinetics of prostaglandin E metabolism in isolated hepatocytes.
- Inhibition of glucagon-stimulated hepatic glycogenolysis by E-series prostaglandins.
- Effect of sodium salicylate on hormonal responses to hypoglycaemia in type II diabetics.
- Effects of antihypertensive drugs on endocrine function.
- Effect of nonsteroidal anti-inflammatory drugs on glycogenolysis in isolated hepatocytes.
- Inhibition of oxidative metabolism by propionic acid and its reversal by carnitine in isolated rat hepatocytes.
- Effect of alpha-ketobutyrate on palmitic acid and pyruvate metabolism in isolated rat hepatocytes.
- Effect of ethanol on intracellular ionized calcium concentrations in synaptosomes and hepatocytes.
- Carnitine metabolism during exercise in patients with peripheral vascular disease.
- Effects of alpha-ketobutyrate and alpha-hydroxybutyrate on the enzymatic determination of acetoacetate and beta-hydroxybutyrate.
- Drug concentrations. A guide to their usefulness in clinical practice.
- Fasting-induced changes in prostaglandin binding in isolated hepatocytes and liver plasma membranes.
- Non-Inferiority Doesn't Mean Not Inferior.
Schools
Case Western Reserve University School of Medicine
Doctors Specialties
- Internal Medicine
- Family Medicine
Accepted Insurances
Awards
- Whos Who in Medicine and Healthcare
Education
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University of Washington -
Case Western Reserve University School of Medicine
Hospital
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Ronald Reagan UCLA Medical Center
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