Physician
Pediatrics
Dr. Eric J. Jenkinson, MD
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Eric J. Jenkinson practices Pediatrics. He went to medical school at Indiana University School of Medicine. Indiana University School of Medicine is ranked 45 in research and 47 in primary care medicine He received 1 awards: "Meaningful Use Stage 1 Certification". Doctor Eric J. Jenkinson, MD is also a published doctor. He has 101 publication published. The most recent publication is: In vitro models of T cell development. Eric Jenkinson is registered with Medicare.
Publications
- Working in paediatric emergency medicine.
- Clonal Analysis Reveals Uniformity in the Molecular Profile and Lineage Potential of CCR9+ and CCR9- Thymus-Settling Progenitors.
- Multiple suppression pathways of canonical Wnt signalling control thymic epithelial senescence.
- Wnt-4 Protects Thymic Epithelial Cells Against Dexamethasone-Induced Senescence.
- Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells.
- Splenic stromal cells mediate IL-7 independent adult lymphoid tissue inducer cell survival.
- Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence.
- Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult.
- A roadmap for thymic epithelial cell development.
- Transplantation of embryonic spleen tissue reveals a role for adult non-lymphoid cells in initiating lymphoid tissue organization.
- Checkpoints in the development of thymic cortical epithelial cells.
- Bringing the thymus to the bench.
- An epithelial progenitor pool regulates thymus growth.
- TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation.
- Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues.
- Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input.
- AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity.
- Reaggregate thymus cultures.
- Preparation of 2-dGuo-treated thymus organ cultures.
- Generating intrathymic microenvironments to establish T-cell tolerance.
- Role of CD30 in B/T segregation in the spleen.
- Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.
- EphrinB1-EphB signaling regulates thymocyte-epithelium interactions involved in functional T cell development.
- Redefining epithelial progenitor potential in the developing thymus.
- Chemokine receptor expression defines heterogeneity in the earliest thymic migrants.
- CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair.
- RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla.
- Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen.
- PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches.
- Fetal thymus organ culture.
- Investigating central tolerance with reaggregate thymus organ cultures.
- Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development.
- Neonatal and adult CD4+ CD3- cells share similar gene expression profile, and neonatal cells up-regulate OX40 ligand in response to TL1A (TNFSF15).
- The thymus and T-cell commitment: the right niche for Notch?
- Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium.
- Establishment and functioning of intrathymic microenvironments.
- Development of functional thymic epithelial cells occurs independently of lymphostromal interactions.
- T/B lineage choice occurs prior to intrathymic Notch signaling.
- OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand express...
- A stroma-derived defect in NF-kappaB2-/- mice causes impaired lymph node development and lymphocyte recruitment.
- Modeling TCR signaling complex formation in positive selection.
- Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb.
- Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors.
- Cutting edge: a chemical genetic system for the analysis of kinases regulating T cell development.
- Thymic epithelial cells provide WNT signals to developing thymocytes.
- Con A activates an Akt/PKB dependent survival mechanism to modulate TCR induced cell death in double positive thymocytes.
- Microenvironmental regulation of Notch signalling in T cell development.
- Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors.
- Induction of thymocyte positive selection does not convey immediate resistance to negative selection.
- Notch ligand-bearing thymic epithelial cells initiate and sustain Notch signaling in thymocytes independently of T cell receptor signaling.
- Identification and characterization of lymphoid precursors in the murine intestinal epithelium.
- Lymphostromal interactions in thymic development and function.
- Protocols for high efficiency, stage-specific retroviral transduction of murine fetal thymocytes and thymic epithelial cells.
- Specialisation of thymic epithelial cells for positive selection of CD4+8+ thymocytes.
- The role of mesenchyme in thymus development.
- Microenvironmental regulation of T cell development in the thymus.
- An essential role for the IL-7 receptor during intrathymic expansion of the positively selected neonatal T cell repertoire.
- Studies on the role of IL-7 presentation by mesenchymal fibroblasts during early thymocyte development.
- Review article: thymus organ cultures and T-cell receptor repertoire development.
- RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse.
- An essential role for thymic mesenchyme in early T cell development.
- Specialized ability of thymic epithelial cells to mediate positive selection does not require expression of the steroidogenic enzyme p450scc.
- Immune-associated nucleotide-1 (IAN-1) is a thymic selection marker and defines a novel gene family conserved in plants.
- Positive selection of thymocytes: the long and winding road.
- Cellular and matrix interactions during the development of T lymphocytes.
- CD69 expression discriminates MHC-dependent and -independent stages of thymocyte positive selection.
- Factors regulating stem cell recruitment to the fetal thymus.
- A novel method of cell separation based on dual parameter immunomagnetic cell selection.
- In vitro models of T cell development.
- Studies on the phenotype of migrant thymic stem cells.
- Differential effects of peptide diversity and stromal cell type in positive and negative selection in the thymus.
- Use of explant technology in the study of in vitro immune responses.
- Studies on thymic epithelial cells in vitro.
- Identification of a developmentally regulated phase of postselection expansion driven by thymic epithelium.
- Cellular interactions in the thymus regulate the protein kinase C signaling pathway.
- Anti-alpha 4 integrin antibody induces apoptosis in murine thymocytes and staphylococcal enterotoxin B-activated lymph node T cells.
- Discrimination between maintenance- and differentiation-inducing signals during initial and intermediate stages of positive selection.
- Piecing together the thymic puzzle.
- Fibroblast dependency during early thymocyte development maps to the CD25+ CD44+ stage and involves interactions with fibroblast matrix molecules.
- Intracellular signaling pathways involved in the induction of apoptosis in immature thymic T lymphocytes.
- Involvement of LFA-1/ICAM-2 adhesive interactions and PKC in activation-induced cell death following SEB rechallenge.
- Cellular interactions in thymocyte development.
- Positive selection of thymocytes involves sustained interactions with the thymic microenvironment.
- Stimulation of thymocytes before and after positive selection results in the induction of different NF-kappa B/Rel protein complexes.
- Phosphatidylinositol 4,5-bisphosphate hydrolysis accompanies T cell receptor-induced apoptosis of murine thymocytes within the thymus.
- The role of the thymus during T-lymphocyte development in vitro.
- Intracellular signaling events during positive and negative selection of CD4+CD8+ thymocytes in vitro.
- The role of macrophages and bone marrow-derived dendritic cells in the rejection of fetal thymus allografts.
- Characteristics of an in vitro system of thymocyte positive selection.
- Thymic epithelial cells provide unique signals for positive selection of CD4+CD8+ thymocytes in vitro.
- Differential expression of Mtv loci in MHC class II-positive thymic stromal cells.
- Fetal thymic organ cultures.
- Developmental regulation of bcl-2 expression in the thymus.
- Positive selection by purified MHC class II+ thymic epithelial cells in vitro: costimulatory signals mediated by B7 are not involved.
- Analysis of cytokine gene expression in subpopulations of freshly isolated thymocytes and thymic stromal cells using semiquantitative polymerase chain reaction.
- MHC class II-positive epithelium and mesenchyme cells are both required for T-cell development in the thymus.
- Apoptosis and T-cell repertoire selection in the thymus.
- Effects of the thymic microenvironment on the response of thymocytes to stimulation.
- Studies on T cell maturation on defined thymic stromal cell populations in vitro.
- Inositol lipids and phosphates in the proliferation and differentiation of lymphocytes and myeloid cells.
Schools
Indiana University School Of Medicine
Devos Chldrns Hospital Spectrum Health
Cen Ind Sports Med Ball Meml
Doctors Specialties
- Pediatric Sports Medicine
- Pediatrics
Accepted Insurances
Awards
- Meaningful Use Stage 1 Certification
Education
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Indiana University School of Medicine
Drug Facts
| NPI NUMBER | 1427057132 | |
| NPPES Provider LastName | JENKINSON | |
| NPPES Provider FirstName | ERIC | |
| NPPES Provider ZIPCode | 468255822 | |
| NPPES Provider State | IN | |
| Specialty Description | Physical Medicine and Rehabilitation | |
| Total Claim Count | 1066.0 | |
| Distinct Opioid Count | 4.0 | |
| Opioid Claim Count | 363.0 | |
| Percent Opioid Claims | 34.05 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1427057132 |
| Last Name Of The Provider | JENKINSON |
| First Name Of The Provider | ERIC |
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