Director, Cardiovascular Translational Medicine, Novartis Institutes for Biomedical Research
Cardiology
Dr. Eric C. Svensson, MD
Eric Svensson works in the field of Cardiology. He researched medicine at David Geffen School of Medicine at UCLA. David Geffen School of Medicine at UCLA is a one of the best medicals schools. David Geffen School of Medicine at UCLA has a rank of 13 in research and a 7 in primary care He has 3 awards "CMS Meaningful Use Stage 1 Certification", "Elected Member" and "Fellow (FACC)". Dr. Eric C. Svensson is a published physician as well. He has 32 publications published. The latest was: Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes.
Publications
- FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during Heart development.
- Particulate Matter Induces Cardiac Arrhythmias via Dysregulation of Carotid Body Sensitivity and Cardiac Sodium Channels.
- A double abdominal Aorta with a double inferior vena cava: A human congenital vascular patterning defect.
- Deciphering the signals specifying the proepicardium.
- Epigenetic attenuation of mitochondrial superoxide dismutase 2 in Pulmonary arterial hypertension: a basis for excessive cell proliferation and a new therapeutic target.
- Epicardial-myocardial signaling directing Coronary vasculogenesis.
- Alternative promoter and GATA5 transcripts in mouse.
- Look who's talking: FGFs and BMPs in the proepicardium.
- Setting the pace: Tbx3 and Tbx18 in cardiac conduction system development.
- Translational control of FOG-2 expression in cardiomyocytes by microRNA-130a.
- Increased FOG-2 in failing myocardium disrupts thyroid hormone-dependent SERCA2 gene transcription.
- An alternative transcript of the FOG-2 gene encodes a FOG-2 isoform lacking the FOG repression motif.
- FOG-2 attenuates endothelial-to-mesenchymal transformation in the endocardial cushions of the developing Heart.
- Fog1 is required for cardiac looping in zebrafish.
- The N termini of Friend of GATA (FOG) proteins define a novel transcriptional repression motif and a superfamily of transcriptional repressors.
- Ets1 is required for proper migration and differentiation of the cardiac neural crest.
- FOG-1-mediated recruitment of NuRD is required for cell lineage re-enforcement during haematopoiesis.
- The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.
- A functionally conserved N-terminal domain of the friend of GATA-2 (FOG-2) protein represses GATA4-dependent transcription.
- Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes.
- A Syndrome of tricuspid atresia in mice with a targeted mutation of the gene encoding Fog-2.
- Cardiac-specific overexpression of dominant-negative CREB leads to increased mortality and mitochondrial dysfunction in female mice.
- Tissue-specific alternative splicing of the beta-galactoside alpha 2,6-sialyltransferase gene.
- Organization of the beta-galactoside alpha 2,6-sialyltransferase gene. Evidence for the transcriptional regulation of terminal glycosylation.
- Efficient and stable transduction of cardiomyocytes after intramyocardial injection or intraCoronary perfusion with recombinant adeno-associated virus vectors.
- Regulated expression of alpha 2,6-sialyltransferase by the liver-enriched transcription factors HNF-1, DBP, and LAP.
- Long-term expression of erythropoietin in the systemic circulation of mice after intramuscular injection of a plasmid DNA vector.
- Muscle-based gene therapy: realistic possibilities for the future.
- Long-term erythropoietin expression in rodents and non-human primates following intramuscular injection of a replication-Defective adenoviral vector.
- Adenoviral-mediated gene transfer of a constitutively active form of the retinoblastoma gene product attenuates neointimal thickening in experimental vein grafts.
- The c-Ha-ras oncogene induces increased expression of beta-galactoside alpha-2, 6-sialyltransferase in rat fibroblast (FR3T3) cells.
Schools
David Geffen School Of Medicine At UCLA University Of California Los Angeles
University of Chicago
Procedures Preformed
- Ablation for Treatment of Cardiac Arrhythmias
- Cardiac Catheterization (incl. Coronary Angiography)
- Cardiac Imaging
- Cardiac MRI (Magnetic Resonance Imaging) of Heart or Chest
- View All
Conditions Treated
- Angina and Acute Coronary Syndrome
- Aortic Aneurysm
- Aortic Ectasia
- Aortic Valve Disease
- View All
Doctors Specialties
- Cardiology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Elected Member
- Fellow (FACC)
Education
-
University of Chicago -
David Geffen School of Medicine at UCLA
Hospital
-
University of Chicago Medical Center
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