Assistant Professor, Neurology, University of Pittsburgh School of Medicine
Neurology
Dr. Edward A. Burton, MD
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Edward Burton practices Neurology. He received 1 awards: "CMS Meaningful Use Stage 1 Certification". Doctor Edward A. Burton, MD is also a published doctor. He has 43 paper published. The most recent paper is: Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase. He accepts Medicare payments and is listed with Medicare.gov.
Publications
- Different Mechanisms Regulate Expression of Zebrafish Myelin Protein Zero (P0) in Myelinating Oligodendrocytes and Its Induction following Axonal Injury.
- Quantification of larval zebrafish motor function in multiwell plates using open-source MATLAB applications.
- The Zebrafish Homologue of the Human DYT1 Dystonia Gene Is Widely Expressed in CNS Neurons but Non-Essential for Early Motor System Development.
- Hypokinesia and reduced dopamine levels in zebrafish lacking ?- and ?1-synucleins.
- Claudin k is specifically expressed in cells that form myelin during development of the nervous system and regeneration of the optic nerve in adult zebrafish.
- Evaluation of spontaneous propulsive movement as a screening tool to detect rescue of Parkinsonism phenotypes in zebrafish models.
- Major isoform of zebrafish P0 is a 23.5 kDa myelin glycoprotein expressed in selected white matter tracts of the central nervous system.
- Single-cell redox imaging demonstrates a distinctive response of dopaminergic neurons to oxidative insults.
- Pseudotype-dependent lentiviral transduction of astrocytes or neurons in the rat substantia nigra.
- Genetic zebrafish models of neurodegenerative Diseases.
- Of fish, flies, worms and men: powerful approaches to neuropsychiatric Disease using genetic models.
- Survival of transplanted neural progenitor cells enhanced by brain irradiation.
- Soluble V domain of Nectin-1/HveC enables entry of herpes simplex virus type 1 (HSV-1) into HSV-resistant cells by binding to viral glycoprotein D.
- The stable 2.0-kilobase intron of the herpes simplex virus type 1 latency-associated transcript does not function as an antisense repressor of ICP0 in nonneuronal cells.
- Use of the herpes simplex viral genome to construct gene therapy vectors.
- Gene delivery using herpes simplex virus vectors.
- A- and B-utrophin have different expression patterns and are differentially up-regulated in mdx muscle.
- Muscular dystrophy--reason for optimism?
- Binding of src-like kinases to the beta-subunit of the interleukin-3 receptor.
- Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase.
- Giant cell arteritis of the cervical radicular vessels presenting with diaphragmatic weakness.
- Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase.
- Induction of utrophin gene expression by heregulin in skeletal muscle cells: role of the N-box motif and GA binding protein.
- Gene therapy progress and prospects: Parkinson''s Disease.
- Targeting gene expression using HSV vectors.
- Muscle and neural isoforms of agrin increase utrophin expression in cultured myotubes via a transcriptional regulatory mechanism.
- The role of basal and myogenic factors in the transcriptional activation of utrophin promoter A: implications for therapeutic up-regulation in Duchenne muscular dystro...
- Cis-acting elements responsible for dopaminergic neuron-specific expression of zebrafish slc6a3 (dopamine transporter) in vivo are located remote from the transcriptio...
- Herpes simplex virus RNAi and neprilysin gene transfer vectors reduce accumulation of Alzheimer''s Disease-related amyloid-beta peptide in vivo.
- HSV trafficking and development of gene therapy vectors with applications in the nervous system.
- Multiple applications for replication-defective herpes simplex virus vectors.
- A second promoter provides an alternative target for therapeutic up-regulation of utrophin in Duchenne muscular dystrophy.
- Replication-defective genomic herpes simplex vectors: design and production.
- Delivery using herpes simplex virus: an overview.
- Expression of a 12-kb promoter element derived from the zebrafish enolase-2 gene in the zebrafish visual system.
- Generation of a transgenic zebrafish model of Tauopathy using a novel promoter element derived from the zebrafish eno2 gene.
- Zebrafish DJ-1 is evolutionarily conserved and expressed in dopaminergic neurons.
- Replication-defective genomic HSV gene therapy vectors: design, production and CNS applications.
- Zebrafish models of Tauopathy.
- Bioenergetics of neurons inhibit the translocation response of Parkin following rapid mitochondrial depolarization.
- Automated measurement of zebrafish larval movement.
- Transgenic zebrafish models of neurodegenerative Diseases.
Procedures Preformed
- Non-Cosmetic Chemodenervation
Conditions Treated
- Ataxia
- Diabetic Polyneuropathy
- Dystonia
- Essential Tremor
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Doctors Specialties
- Neurology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Hospital
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UPMC Presbyterian Shadyside
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