Professor, Pediatrics, University Massachusetts Medical School
Infectious Disease
Dr. Donna M. Ambrosino, MD
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Donna Ambrosino is an expert in the field of Infectious Disease. She went to Geisel School of Medicine at Dartmouth. Geisel School of Medicine at Dartmouth has a rank of 37 in research and a 29 in primary care Doctor Donna M. Ambrosino, MD is also published. She has 72 publications published. The lastest publication: "Normal IgG and impaired IgM responses to polysaccharide vaccines in asplenic patients.'
Publications
- History of passive antibody administration for prevention and treatment of infectious diseases.
- Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study.
- Treatment with monoclonal antibodies against Clostridium difficile toxins.
- Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus.
- Recombinant protein-based assays for detection of antibodies to severe acute respiratory syndrome coronavirus spike and nucleocapsid proteins.
- Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters.
- Therapy with a severe acute respiratory syndrome-associated coronavirus-neutralizing human monoclonal antibody reduces disease severity and viral burden in golden Syri...
- Development and characterization of a severe acute respiratory syndrome-associated coronavirus-neutralizing human monoclonal antibody that provides effective immunopro...
- CD209L (L-SIGN) is a receptor for severe acute respiratory syndrome coronavirus.
- Amino acids 270 to 510 of the severe acute respiratory syndrome coronavirus spike protein are required for interaction with receptor.
- Donor immunization with pneumococcal conjugate vaccine and early protective antibody responses following allogeneic hematopoietic cell transplantation.
- High-Throughput Sequencing Analysis of Post-Liver Transplantation HCV E2 Glycoprotein Evolution in the Presence and Absence of Neutralizing Monoclonal Antibody.
- Identification of Human Monoclonal Antibodies Specific for Human SOD1 Recognizing Distinct Epitopes and Forms of SOD1.
- Effect of intravenous gammaglobulin therapy in IgG2 deficient and IgG2 sufficient children with recurrent infections and poor response to immunization with Hemophilus ...
- Prevention of pneumococcal otitis media in chinchillas with human bacterial polysaccharide immune globulin.
- Effects of alum adjuvant or a booster dose on immunogenicity during clinical trials of group B streptococcal type III conjugate vaccines.
- Management of persistent chylothorax.
- Rifampin chemoprophylaxis for household contacts of patients with invasive infections due to Haemophilus influenzae type b.
- Trimethoprim and rifampin in combination for chemoprophylaxis of household contacts of patients with invasive infections due to Haemophilus influenzae type b.
- Rifampin alone and in combination with trimethoprim in chemoprophylaxis for infections due to Haemophilus influenzae type b.
- Efficacy of human hyperimmune globulin in prevention of Haemophilus influenzae type b disease in infant rats.
- Straight talk with...Donna Ambrosino. Interview by Elie Dolgin.
- Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI).
- Successful treatment of Cryptococcal meningitis with a combination of liposomal amphotericin B, flucytosine and posaconazole: two case reports.
- Identification and characterization of a human monoclonal antibody that potently neutralizes a broad panel of rabies virus isolates.
- Effect of monophosphoryl lipid A (MPL) on T-helper cells when administered as an adjuvant with pneumocococcal-CRM197 conjugate vaccine in healthy toddlers.
- G glycoprotein amino acid residues required for human monoclonal antibody RAB1 neutralization are conserved in rabies virus street isolates.
- Monoclonal antibodies to SARS-associated coronavirus (SARS-CoV): identification of neutralizing and antibodies reactive to S, N, M and E viral proteins.
- Comparison of an opsonophagocytic assay and IgG ELISA to assess responses to pneumococcal polysaccharide and pneumococcal conjugate vaccines in children and young adul...
- Enzyme-linked immunosorbent assay to assess respiratory syncytial virus concentration and correlate results with inflammatory mediators in tracheal secretions.
- Normal IgG and impaired IgM responses to polysaccharide vaccines in asplenic patients.
- Comparison of multiple immunization schedules for Haemophilus influenzae type b-conjugate and tetanus toxoid vaccines following bone marrow transplantation.
- Reduction of respiratory syncytial virus (RSV) in tracheal aspirates in intubated infants by use of humanized monoclonal antibody to RSV F protein.
- Respiratory syncytial virus vaccines.
- Antibody responses to tetanus toxoid and Haemophilus influenzae type b conjugate vaccines following autologous peripheral blood stem cell transplantation (PBSCT).
- Haemophilus influenzae type b (HIB)-conjugate immunization before bone marrow harvest in autologous bone marrow transplantation.
- Donor immunization with Haemophilus influenzae type b (HIB)-conjugate vaccine in allogeneic bone marrow transplantation.
- Pneumococcal conjugate vaccine primes for antibody responses to polysaccharide pneumococcal vaccine after treatment of Hodgkin's disease.
- Clonal characterization of the human IgG antibody repertoire to Haemophilus influenzae type b polysaccharide. V. In vivo expression of individual antibody clones is de...
- Bacterial polysaccharide immune globulin for prophylaxis of acute otitis media in high-risk children.
- Critical appraisal of immunization strategies for prevention of infection in the compromised host.
- T cells and natural killer cells regulate human IgG subclass concentrations in SCID mice.
- Recombinant interleukin-2 infusions and decreased IgG2 subclass concentrations.
- Impaired human responses to tetanus toxoid in vitamin A-deficient SCID mice reconstituted with human peripheral blood lymphocytes.
- Antibody responses to polysaccharide and polysaccharide-conjugate vaccines after treatment of Hodgkin disease.
- Blood-group-A-like substance in a preparation of pneumococcal vaccine.
- Selective defect in the antibody response to Haemophilus influenzae type b in children with recurrent infections and normal serum IgG subclass levels.
- Correlations of G2m(n) and Km(1) allotypes with subclass- and light-chain-specific antibody.
- Correlation of the Km(1) immunoglobulin allotype with anti-polysaccharide antibodies in Caucasian adults.
- Antibody response of infants to Haemophilus influenzae type b capsular polysaccharide combined with Bordetella pertussis.
- Ig allotype-linked regulation of class and subclass composition of natural antibodies to group A streptococcal carbohydrate.
- Proliferation of resting B cells is modulated by CR2 and CR1.
- Prevention of Haemophilus influenzae type b infections in high-risk infants treated with bacterial polysaccharide immune globulin.
- Interpretation of IgG subclass values: a comparison of two assays.
- Kappa and lambda light chain composition of antibody to the capsular polysaccharide of Haemophilus influenzae type b.
- Human polysaccharide-specific B cells are responsive to pokeweed mitogen and IL-6.
- Immunoglobulin G subclass values in healthy black and white children.
- Human B cells secrete predominantly lambda L chains in the absence of H chain expression.
- Impaired polysaccharide responses in immunodeficient patients: relevance to bone marrow transplant patients.
- Effect of Haemophilus influenzae polysaccharide outer membrane protein complex conjugate vaccine on macrophages.
- IgG1, IgG2 and IgM responses to two Haemophilus influenzae type b conjugate vaccines in young infants.
- Response to Haemophilus influenzae type B conjugate vaccine in children undergoing splenectomy.
- Correlation between G2m(n) immunoglobulin allotype and human antibody response and susceptibility to polysaccharide encapsulated bacteria.
- Recurrent sinopulmonary infection and impaired antibody response to bacterial capsular polysaccharide antigen in children with selective IgG-subclass deficiency.
- Children with selective IgG subclass deficiency and recurrent sinopulmonary infection: impaired response to bacterial capsular polysaccharide antigens.
- Haemophilus influenzae type b unsuspected bacteremia.
- An immunodeficiency characterized by impaired antibody responses to polysaccharides.
- Simultaneous administration of vaccines for Haemophilus influenzae type b, pneumococci, and meningococci.
- Passive immunization against disease due to Haemophilus influenzae type b: concentrations of antibody to capsular polysaccharide in high-risk children.
- Impaired antibody responses in the hyperimmunoglobulin E syndrome.
- Preparation of human hyperimmune globulin to Haemophilus influenzae b, Streptococcus pneumoniae, and Neisseria meningitidis.
Schools
Dartmouth College
Dartmouth Hitchcock
Children39s Hospital Boston
Dana Farber Cancer Institute
Doctors Specialties
- Pediatrics
- Infectious Disease
Accepted Insurances
Education
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Boston Children's Hospital -
Dartmouth-Hitchcock Medical Center -
Geisel School of Medicine at Dartmouth
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