Professor, Internal Medicine, University of Utah School of Medicine
Infectious Disease
Dr. Donald L. Granger, MD
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Donald L. Granger, MD is an expert in the field of Infectious Disease. He went to University of Utah School of Medicine. Donald Granger is a published physician as well. He has 61 publications published. The latest was: Measuring nitric oxide production in human clinical studies.
Publications
- Impaired systemic tetrahydrobiopterin bioavailability and increased oxidized biopterins in pediatric falciparum malaria: association with disease severity.
- Quantification of Plasmodium falciparum Histidine-Rich Protein-2 in Cerebral Spinal Fluid from Cerebral Malaria Patients.
- Dimethylarginines: endogenous inhibitors of nitric oxide synthesis in children with falciparum malaria.
- Plasma Plasmodium falciparum Histidine-Rich Protein-2 Concentrations Are Associated with Malaria Severity and Mortality in Tanzanian Children.
- Age-related susceptibility to severe malaria associated with galectin-2 in highland Papuans.
- Increased asymmetric dimethylarginine in severe falciparum malaria: association with impaired nitric oxide bioavailability and fatal outcome.
- Relationship of cell-free hemoglobin to impaired endothelial nitric oxide bioavailability and perfusion in severe falciparum malaria.
- Arginine, nitric oxide, carbon monoxide, and endothelial function in severe malaria.
- Recovery of endothelial function in severe falciparum malaria: relationship with improvement in plasma L-arginine and blood lactate concentrations.
- Safety profile of L-arginine infusion in moderately severe falciparum malaria.
- Impaired nitric oxide bioavailability and L-arginine reversible endothelial dysfunction in adults with falciparum malaria.
- Elevated plasma phenylalanine in severe malaria and implications for pathophysiology of neurological complications.
- Impaired systemic production of prostaglandin E2 in children with cerebral malaria.
- Salmonella enterica serovar Typhimurium RamA, intracellular oxidative stress response, and bacterial virulence.
- Inducible nitric oxide synthase (NOS2) promoter CCTTT repeat polymorphism: relationship to in vivo nitric oxide production/NOS activity in an asymptomatic malaria-ende...
- Major histocompatibility complex-dependent susceptibility to Cryptococcus neoformans in mice.
- Injury of neoplastic cells by murine macrophages leads to inhibition of mitochondrial respiration.
- Macrophage production of nitrogen oxides in host defence against microorganisms.
- Mitochondrial iron loss from leukemia cells injured by macrophages. A possible mechanism for electron transport chain defects.
- Macrophage-mediated fungistasis in vitro: requirements for intracellular and extracellular cytotoxicity.
- Do natural killer cells help protect us from disease caused by pathogenic fungi?
- Macrophage-mediated fungistasis: requirement for a macromolecular component in serum.
- Cutaneous granulomatous response to BCG cell walls with reference to cancer immunotherapy.
- Effects of antifungal agents and gamma interferon on macrophage cytotoxicity for fungi and tumor cells.
- Efficacy of immune therapy in early experimental Naegleria fowleri meningitis.
- Noncardiogenic pulmonary edema during vivax malaria.
- Comparison of oral and tympanic temperatures in a Veterans Administration outpatient clinic.
- Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction.
- Nitrate levels in malaria.
- Growth inhibition of Cryptococcus neoformans by human alveolar macrophages.
- Bartonella henselae: etiology of pulmonary nodules in a patient with depressed cell-mediated immunity.
- Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxide.
- High-output nitric oxide: weapon against infection?
- Urinary nitrate excretion in relation to murine macrophage activation. Influence of dietary L-arginine and oral NG-monomethyl-L-arginine.
- Specific amino acid (L-arginine) requirement for the microbiostatic activity of murine macrophages.
- Neutralization of gamma interferon and tumor necrosis factor alpha blocks in vivo synthesis of nitrogen oxides from L-arginine and protection against Francisella tular...
- Metabolic fate of L-arginine in relation to microbiostatic capability of murine macrophages.
- Cerebrospinal fluid macrophage response to experimental cryptococcal meningitis: relationship between in vivo and in vitro measurements of cytotoxicity.
- Nitric oxide produced during murine listeriosis is protective.
- Opsonic activity of cerebrospinal fluid in experimental cryptococcal meningitis.
- Effect of in vivo inhibition of nitric oxide production in murine leishmaniasis.
- Human immunodeficiency virus (HIV)-infected human blood monocytes and peritoneal macrophages have reduced anticryptococcal activity whereas HIV-infected alveolar macro...
- N omega -monomethyl-L-arginine inhibits nitric oxide production in murine cardiac allografts but does not affect graft rejection.
- Measuring nitric oxide production in human clinical studies.
- A promoter polymorphism in the gene encoding interleukin-12 p40 (IL12B) is associated with mortality from cerebral malaria and with reduced nitric oxide production.
- Human alveolar and peritoneal macrophages mediate fungistasis independently of L-arginine oxidation to nitrite or nitrate.
- Inhibition of Cryptococcus neoformans replication by nitrogen oxides supports the role of these molecules as effectors of macrophage-mediated cytostasis.
- Structure and biological activities of acapsular Cryptococcus neoformans 602 complemented with the CAP64 gene.
- Cryptococcus neoformans fails to induce nitric oxide synthase in primed murine macrophage-like cells.
- Nitric oxide synthase type 2 promoter polymorphisms, nitric oxide production, and disease severity in Tanzanian children with malaria.
- The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lp...
- Effects of age and parasitemia on nitric oxide production/leukocyte nitric oxide synthase type 2 expression in asymptomatic, malaria-exposed children.
- Nitric oxide, malaria, and anemia: inverse relationship between nitric oxide production and hemoglobin concentration in asymptomatic, malaria-exposed children.
- Nitric oxide in Tanzanian children with malaria: inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression.
- Novel Salmonella enterica serovar Typhimurium protein that is indispensable for virulence and intracellular replication.
- Low plasma arginine concentrations in children with cerebral malaria and decreased nitric oxide production.
- A new NOS2 promoter polymorphism associated with increased nitric oxide production and protection from severe malaria in Tanzanian and Kenyan children.
- Major histocompatibility complex controls the trajectory but not host-specific adaptation during virulence evolution of the pathogenic fungus Cryptococcus neoformans.
- Malaria severity and human nitric oxide synthase type 2 (NOS2) promoter haplotypes.
- A study of the TNF/LTA/LTB locus and susceptibility to severe malaria in highland papuan children and adults.
Schools
University of Utah
Doctors Specialties
- Internal Medicine
- Infectious Disease
Accepted Insurances
Education
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University of Utah -
University of Rochester -
University of Utah School of Medicine
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