Physician
Neurology
Dr. Dennis R. Groothuis, MD
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Dennis Groothuis is an expert in the field of Neurology. He researched medicine at University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine is ranked 10/19 in Research/PrimaryCare. He received 1 awards: "CMS Meaningful Use Stage 1 Certification". Doctor Dennis R. Groothuis, MD is a published doctor. He published 77 publications, including: 'Comparison of 14C-sucrose delivery to the brain by intravenous, intraventricular, and convection-enhanced intracerebral infusion.' Dennis Groothuis accepts Medicare payments and is registered with Medicare.gov.
Publications
- Hematopoietic growth factors pass through the blood-brain barrier in intact rats.
- Efflux of drugs and solutes from brain: the interactive roles of diffusional transcapillary transport, bulk flow and capillary transporters.
- Therapeutic implications of tumor interstitial fluid pressure in subcutaneous RG-2 tumors.
- Isolation of drug delivery from drug effect: problems of optimizing drug delivery parameters.
- Comparative pharmacokinetics of 14C-sucrose in RG-2 rat gliomas after intravenous and convection-enhanced delivery.
- Regional cerebral blood flow in the beagle puppy model of neonatal intraventricular hemorrhage: studies during systemic hypertension.
- Regional variability of blood flow and glucose utilization within the subependymal germinal matrix.
- The entry of antiviral and antiretroviral drugs into the central nervous system.
- Blood-brain barrier integrity in Alzheimer's disease patients and elderly control subjects.
- Changes in blood-brain barrier permeability associated with insertion of brain cannulas and microdialysis probes.
- Comparison of 14C-sucrose delivery to the brain by intravenous, intraventricular, and convection-enhanced intracerebral infusion.
- Absence of host-site influence on angiogenesis, blood flow, and permeability in transplanted RG-2 gliomas.
- Microvessel organization and structure in experimental brain tumors: microvessel populations with distinctive structural and functional properties.
- Comparison of cytosine arabinoside delivery to rat brain by intravenous, intrathecal, intraventricular and intraparenchymal routes of administration.
- The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery.
- The blood-brain barrier in primary CNS lymphomas: ultrastructural evidence of endothelial cell death.
- The human thalamocortical sensory path in the internal capsule: evidence from a small capsular hemorrhage causing a pure sensory stroke.
- Lupus-associated chorea in childhood.
- The effect of an amino acid-lowering diet on the rate of melphalan entry into brain and xenotransplanted glioma.
- Monoclonal antibody localization in subcutaneous and intracranial human glioma xenografts: paired-label and imaging analysis.
- Murine sarcoma virus-induced brain tumors. Concurrent measurements of blood flow and transcapillary transport.
- Regional measurements of blood flow in experimental RG-2 rat gliomas.
- Regional measurements of blood-to-tissue transport in experimental RG-2 rat gliomas.
- A model for human medulloblastoma. Growth, morphology, and chromosomal analysis in vitro and in athymic mice.
- Permeability of different experimental brain tumor models to horseradish peroxidase.
- Regional cerebral blood flow in the newborn beagle pup: the germinal matrix is a "low-flow" structure.
- Demyelinating radiculopathy in the Kearns-Sayre syndrome: a clinicopathological study.
- Dominantly inherited pseudohypertrophic muscular dystrophy with internalized capillaries.
- The effect of L-amino acid oxidase on activity of melphalan against an intracranial xenograft.
- A new head holder for reducing axial movement and repositioning errors during physiological CT imaging.
- Noninvasive measurement of arterial blood plasma concentration of iodinated contrast agents from CT scans of human brain.
- Noninvasive CT determination of arterial blood concentration of meglumine iothalamate.
- The effects of dexamethasone on experimental brain tumors: I. Transcapillary transport and blood flow in RG-2 rat gliomas.
- The effects of dexamethasone on transcapillary transport in experimental brain tumors: II. Canine brain tumors.
- A method to quantitatively measure transcapillary transport of iodinated compounds in canine brain tumors with computed tomography.
- Quantitative measurements of capillary transport in human brain tumors by computed tomography.
- Blood flow and blood-to-tissue transport in 9L gliosarcomas: the role of the brain tumor model in drug delivery research.
- Blood-tumor barrier disruption controversies.
- Potential errors due to aliasing in digital video analysis of quantitative autoradiography.
- Effect of hyperosmotic blood-brain barrier disruption on transcapillary transport in canine brain tumors.
- The role of the blood-brain barrier in movement disorders.
- Rate of buthionine sulfoximine entry into brain and xenotransplanted human gliomas.
- The somatosensory evoked potential as a noninvasive method to determine flow rates for hyperosmotic disruption of the blood-brain barrier.
- Vasoactive drugs produce selective changes in flow to experimental brain tumors.
- A glial fibrillary acidic protein-expressing and tumorigenic cell line derived from an avian sarcoma virus-induced rat astrocytoma.
- The effect of hyperosmotic blood-brain barrier disruption on blood-to-tissue transport in ENU-induced gliomas.
- Comparative localization of murine monoclonal antibody Me1-14 F(ab')2 fragment and whole IgG2a in human glioma xenografts.
- Buthionine sulfoximine-mediated depletion of glutathione in intracranial human glioma-derived xenografts.
- Dexamethasone effects on vascular volume and tissue hematocrit in experimental RG-2 gliomas and adjacent brain.
- The effect of systemic arterial hypertension on blood-to-tissue transport in experimental gliomas.
- Concurrent measurements of blood flow and transcapillary transport in xenotransplanted human gliomas in immunosuppressed rats.
- Chemotherapy of brain tumors: physiological and pharmacokinetic considerations.
- Regional localization of a glioma-associated antigen defined by monoclonal antibody 81C6 in vivo: kinetics and implications for diagnosis and therapy.
- Quantitative analysis of cerebral vessels in the newborn puppy: the structure of germinal matrix vessels may predispose to hemorrhage.
- The effect of 125I interstitial radiotherapy on blood-brain barrier function in normal canine brain.
- Intravenous adenosine selectively increases blood flow to xenotransplanted intracerebral gliomas.
- Dexamethasone effects on [125I]albumin distribution in experimental RG-2 gliomas and adjacent brain.
- Focal cerebral vasculitis associated with circulating immune complexes and brain irradiation.
- Simultaneous measurements of blood flow and blood-to-tissue transport in xenotransplanted medulloblastomas.
- Rational brain tumor chemotherapy. The interaction of drug and tumor.
- Autoregulation of cerebral blood flow in the newborn beagle puppy.
- Regional blood flow and blood-to-tissue transport in five brain tumor models. Implications for chemotherapy.
- Comparative permeability of different glioma models to horseradish peroxidase.
- Pleomorphic xanthoastrocytoma. Ultrastructural and immunohistochemical study of a case with a rapidly fatal outcome following surgery.
- Experimental gliomas: an autoradiographic study of the endothelial component.
- Computed tomography of virally induced canine brain tumors: a preliminary report.
- Spatial distribution of proliferating cells in avian sarcoma virus-induced gliomas.
- Alternative delivery systems for antiviral nucleosides and antisense oligonucleotides to the brain.
- Regional blood flow in ethylnitrosourea-induced brain tumors.
- Regional blood-to-tissue transport in ethylnitrosourea-induced brain tumors.
- The effect of graded hypertonic intracarotid infusions on drug delivery to experimental RG-2 gliomas.
- Regional blood-to-tissue transport in avian sarcoma virus (ASV)-induced brain tumors.
- Regional blood flow in avian sarcoma virus (ASV)-induced brain tumors.
- Regional thymidine transport and incorporation in experimental brain and subcutaneous tumors.
- Radiculoneuropathy as a component of the Kearns-Sayre syndrome.
- Do cancers invade veins?
Schools
University Of ChicagoThe Pritzker School Of Medicine
University of Chicago
Procedures Preformed
- EEG (Electroencephalogram)
- EMG (Electromyography)
- MRI (Magnetic Resonance Imaging)
Doctors Specialties
- Neurology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
Education
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Vanderbilt University -
University of Chicago -
University of Chicago Pritzker School of Medicine
Hospital
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NorthShore University Health System -
NorthShore Skokie Hospital
Drug Facts
| NPI NUMBER | 1093874539 | |
| NPPES Provider LastName | GROOTHUIS | |
| NPPES Provider FirstName | DENNIS | |
| NPPES Provider ZIPCode | 602011718 | |
| NPPES Provider State | IL | |
| Specialty Description | Neurology | |
| Total Claim Count | 1293.0 | |
| Distinct Opioid Count | 2.0 | |
| Opioid Claim Count | 82.0 | |
| Percent Opioid Claims | 6.34 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1093874539 |
| Last Name Of The Provider | GROOTHUIS |
| First Name Of The Provider | DENNIS |
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