Siteman Cancer Center/Washington Unviersity / BJH
Radiation Oncology
Dr. Dennis E. Hallahan, MD
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Dennis Hallahan is an expert in the field of Radiation Oncology. He studied medicine at Rush Medical College. He has 16 awards "CMS Meaningful Use Stage 1 Certification", "The Alvin Siteman Cancer Research Award", "Elizabeth H. & James S. McDonnell III Distinguished Professor", "Grant Liddle Award", "High Impact Research Recognition", "Fellow", "Vanderbilt Scholar Award", "Nominee and Finalist: DDCF Distinguished Clinical Scientist Award", "First Award", "Career Development Award", "Best Teaching Medical Resident", "Herrick Research Fellowship", "Deans Research Award", "Phi Kappa Phi Honor Society", "Departmental Honors, Biology" and "James Scholar". Dr. Dennis E. Hallahan is also published. He has 70 publications published. The lastest publication: "Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells.' Dennis E. Hallahan accepts all Medicare patients.
Publications
- Valproic acid enhances the efficacy of radiation therapy by protecting normal hippocampal neurons and sensitizing malignant glioblastoma cells.
- A GSK-3β Inhibitor Protects Against Radiation Necrosis in Mouse Brain.
- Anti-VEGF antibodies mitigate the development of radiation necrosis in mouse brain.
- Thoughts on the future of research, teaching, and testing in the biological sciences of radiation oncology.
- Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models.
- Tax-interacting protein 1 coordinates the spatiotemporal activation of Rho GTPases and regulates the infiltrative growth of human glioblastoma.
- High-throughput identification of putative receptors for cancer-binding peptides using biopanning and microarray analysis.
- Multifunctional FePt nanoparticles for radiation-guided targeting and imaging of cancer.
- Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature.
- Radiation-guided drug delivery to mouse models of lung cancer.
- Cytosolic phospholipase A2 and lysophospholipids in tumor angiogenesis.
- Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors.
- Correlation of quantified contrast-enhanced sonography with in vivo tumor response.
- A new class of molecular targeted radioprotectors: GSK-3beta inhibitors.
- Recombinant peptides as biomarkers for tumor response to molecular targeted therapy.
- Lithium-mediated protection of hippocampal cells involves enhancement of DNA-PK-dependent repair in mice.
- A molecular imaging paradigm to rapidly profile response to angiogenesis-directed therapy in small animals.
- Cytosolic phospholipase A2: targeting cancer through the tumor vasculature.
- Using in vivo biopanning for the development of radiation-guided drug delivery systems.
- A method for assessing the microvasculature in a murine tumor model using contrast-enhanced ultrasonography.
- Inhibition of glycogen synthase kinase 3 beta attenuates neurocognitive dysfunction resulting from cranial irradiation.
- SU11248 (sunitinib) sensitizes pancreatic cancer to the cytotoxic effects of ionizing radiation.
- Relationship between retention of a vascular endothelial growth factor receptor 2 (VEGFR2)-targeted ultrasonographic contrast agent and the level of VEGFR2 expression ...
- Differential efficacy of combined therapy with radiation and AEE788 in high and low EGFR-expressing androgen-independent prostate tumor models.
- Bone marrow X kinase-mediated signal transduction in irradiated vascular endothelium.
- Noninvasive assessment of cancer response to therapy.
- Molecular imaging of vascular endothelial growth factor receptor 2 expression using targeted contrast-enhanced high-frequency ultrasonography.
- Impact of inhomogeneity corrections on dose coverage in the treatment of lung cancer using stereotactic body radiation therapy.
- Measuring tumor perfusion in control and treated murine tumors: correlation of microbubble contrast-enhanced sonography to dynamic contrast-enhanced magnetic resonance...
- HIV protease inhibitors enhance the efficacy of irradiation.
- PDGFR-beta expression in small cell lung cancer patients.
- Noninvasive assessment of tumor vasculature response to radiation-mediated, vasculature-targeted therapy using quantified power Doppler sonography: implications for im...
- Lithium treatment prevents neurocognitive deficit resulting from cranial irradiation.
- Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling.
- Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer.
- Increased expression of nuclear factor E2 p45-related factor 2 (NRF2) in head and neck squamous cell carcinomas.
- Integrin alpha v beta 3 antagonist Cilengitide enhances efficacy of radiotherapy in endothelial cell and non-small-cell lung cancer models.
- Radiation-guided gene therapy of cancer.
- Correlation between estimates of tumor perfusion from microbubble contrast-enhanced sonography and dynamic contrast-enhanced magnetic resonance imaging.
- SRC family kinase inhibitor SU6656 enhances antiangiogenic effect of irradiation.
- Protein kinase B/Akt-dependent phosphorylation of glycogen synthase kinase-3beta in irradiated vascular endothelium.
- Proteolytic surface functionalization enhances in vitro magnetic nanoparticle mobility through extracellular matrix.
- Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining.
- Radiosensitization of lung cancer by nutlin, an inhibitor of murine double minute 2.
- Characterization of superparamagnetic nanoparticle interactions with extracellular matrix in an in vitro system.
- Molecular strategies targeting the host component of cancer to enhance tumor response to radiation therapy.
- STI571 (Gleevec) improves tumor growth delay and survival in irradiated mouse models of glioblastoma.
- The use of tyrosine kinase inhibitors in modifying the response of tumor microvasculature to radiotherapy.
- Inhibition of alpha(v)beta3 integrin survival signaling enhances antiangiogenic and antitumor effects of radiotherapy.
- Murine double minute 2 as a therapeutic target for radiation sensitization of lung cancer.
- DNA-dependent protein kinase is a molecular target for the development of noncytotoxic radiation-sensitizing drugs.
- Sonographic depiction of changes of tumor vascularity in response to various therapies.
- Nuclear survivin predicts recurrence and poor survival in patients with resected nonsmall cell lung carcinoma.
- Sonographic depiction of microvessel perfusion: principles and potential.
- Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway.
- A specific antagonist of the p110delta catalytic component of phosphatidylinositol 3'-kinase, IC486068, enhances radiation-induced tumor vascular destruction.
- Phantom validation of coregistration of PET and CT for image-guided radiotherapy.
- Survivin as a therapeutic target for radiation sensitization in lung cancer.
- Prospective feasibility trial of radiotherapy target definition for head and neck cancer using 3-dimensional PET and CT imaging.
- Broad spectrum receptor tyrosine kinase inhibitor, SU6668, sensitizes radiation via targeting survival pathway of vascular endothelium.
- Quantification of tumor vascularity with contrast-enhanced sonography: correlation with magnetic resonance imaging and fluorodeoxyglucose autoradiography in an implant...
- The Use of Antisense Oligonucleotides in Evaluating Survivin as a Therapeutic Target for Radiation Sensitization in Lung Cancer.
- Growth factor-independent activation of protein kinase B contributes to the inherent resistance of vascular endothelium to radiation-induced apoptotic response.
- FDG PET in the follow-up management of patients with newly diagnosed Hodgkin and non-Hodgkin lymphoma after first-line chemotherapy.
- SU11248 maintenance therapy prevents tumor regrowth after fractionated irradiation of murine tumor models.
- Phosphatidylinositol 3-kinase/Akt signaling in the response of vascular endothelium to ionizing radiation.
- Effects of intercellular adhesion molecule 1 (ICAM-1) null mutation on radiation-induced pulmonary fibrosis and respiratory insufficiency in mice.
- Membrane Phospholipids, EML4-ALK, and Hsp90 as Novel Targets in Lung Cancer Treatment.
- Autotaxin Inhibition with PF-8380 Enhances the Radiosensitivity of Human and Murine Glioblastoma Cell Lines.
Schools
Rush Medical College Of Rush University
University of Chicago
Doctors Specialties
- Radiation Oncology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- The Alvin Siteman Cancer Research Award
- Elizabeth H. & James S. McDonnell III Distinguished Professor
- Grant Liddle Award
- High Impact Research Recognition
- Fellow
- Vanderbilt Scholar Award
- Nominee and Finalist: DDCF Distinguished Clinical Scientist Award
- First Award
- Career Development Award
- Best Teaching Medical Resident
- Herrick Research Fellowship
- Deans Research Award
- Phi Kappa Phi Honor Society
- Departmental Honors, Biology
- James Scholar
Education
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University of Chicago -
Rush Medical College -
University of Illinois
Hospital
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Barnes-Jewish Hospital -
St. Louis Children's Hospital
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1699867010 |
| Last Name Of The Provider | HALLAHAN |
| First Name Of The Provider | DENNIS |
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