Jackson Professor of Clinical Medicine, Massachusetts General Hospital
Nephrology
Dr. Dennis A. Ausiello, MD
|
|
Give Review
Dr. Dennis A. Ausiello practices Nephrology. He attended Perelman School of Medicine at the University of Pennsylvania. He has 3 awards "Fellow (FACP)", "Elected Member" and "Super Doctor". Doctor Dennis A. Ausiello, MD is also a published doctor. He has 101 publication published. The most recent publication is: Brief report: a molecular defect in the vasopressin V2-receptor gene causing nephrogenic diabetes insipidus.
Publications
- Real-Time Assessment of Wellness and Disease in Daily Life.
- Alexander Leaf: in memoriam.
- The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H+-ATPase (V-ATPase) and Cytohesin-2.
- Heterologous downregulation of vasopressin type 2 receptor is induced by transferrin.
- Visualizing Microtubule-Dependent Vasopressin Type 2 Receptor Trafficking Using a New High-Affinity Fluorescent Vasopressin Ligand.
- Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.
- Vasopressin receptor-mediated functional signaling pathway in primary cilia of renal epithelial cells.
- Effects of the renal medullary pH and ionic environment on vasopressin binding and signaling.
- Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R.
- Characterization of single channel currents from primary cilia of renal epithelial cells.
- Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway.
- Preserving creativity in medicine.
- Characterization of Na+-permeable cation channels in LLC-PK1 renal epithelial cells.
- Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situ.
- Functional role of the NPxxY motif in internalization of the type 2 vasopressin receptor in LLC-PK1 cells.
- Global health: a chance for Western physicians to give-and receive.
- The 15% solution for majority health concerns.
- Aquaporin 2 (AQP2) and vasopressin type 2 receptor (V2R) endocytosis in kidney epithelial cells: AQP2 is located in ''endocytosis-resistant'' membrane domains after va...
- V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathway.
- Sensing, signaling and sorting events in kidney epithelial cell physiology.
- Physiological importance of endosomal acidification: potential role in proximal tubulopathies.
- Physical and functional connection between auxilin and dynamin during endocytosis.
- The Clinical Research Forum and Association of American Physicians disagree with criticism of the NIH Roadmap.
- The necessary risks of medical research.
- Science education and communication: AAP Presidential Address.
- Brief report: a molecular defect in the vasopressin V2-receptor gene causing nephrogenic diabetes insipidus.
- Transcriptional regulation of G-protein alpha i subunit genes in LLC-PK1 renal cells and characterization of the porcine G alpha 1-3 gene promoter.
- Basic science research.
- A Null mutation in the vasopressin V2 receptor gene (AVPR2) associated with nephrogenic diabetes insipidus in the Hopewell kindred.
- Activation of epithelial Na+ channels by protein kinase A requires actin filaments.
- Vasopressin and protein kinase A activate G protein-sensitive epithelial Na+ channels.
- Actin-binding protein contributes to cell volume regulatory ion channel activation in melanoma cells.
- Entry of cholera toxin into polarized human intestinal epithelial cells. Identification of an early brefeldin A sensitive event required for A1-peptide generation.
- Nephrogenic diabetes insipidus: causes revealed.
- Binding of the cytosolic p200 protein to Golgi membranes is regulated by heterotrimeric G proteins.
- Targeting of chimeric G alpha i proteins to specific membrane domains.
- Mutations in the vasopressin V2 receptor gene in two families with nephrogenic diabetes insipidus.
- Effects of P-glycoprotein expression on cyclic AMP and volume-activated ion fluxes and conductances in HT-29 colon adenocarcinoma cells.
- Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study.
- Renal tubular transport mechanisms.
- Protein kinase C mediates down-regulation of cystic fibrosis transmembrane conductance regulator levels in epithelial cells.
- Constitutive and regulated membrane expression of aquaporin 1 and aquaporin 2 water channels in stably transfected LLC-PK1 epithelial cells.
- cAMP-independent regulation of CFTR by the actin cytoskeleton.
- A basolateral CHIP28/MIP26-related protein (BLIP) in kidney principal cells and gastric parietal cells.
- A 28 kDa sarcolemmal antigen in kidney principal cell basolateral membranes: relationship to orthogonal arrays and MIP26.
- The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.
- External ATP and its analogs activate the cystic fibrosis transmembrane conductance regulator by a cyclic AMP-independent mechanism.
- Heterologous expression of delta F508 CFTR results in decreased sialylation of membrane glycoconjugates.
- Induction of multidrug resistance downregulates the expression of CFTR in colon epithelial cells.
- Regulation of vasopressin-sensitive adenylate cyclase by calmodulin.
- Na+-dependent sugar transport in a cultured epithelial cell line from pig kidney.
- Regulation of vasopressin binding to intact cells.
- A role for calmodulin in the activation of adenylate cyclase by vasopressin.
- Radiation inactivation of oligomeric enzyme systems: theoretical considerations.
- The role of calcium in the stimulation of prostaglandin synthesis by vasopressin in rabbit renal-medullary interstitial cells in tissue culture.
- Identification of actin-binding protein and villin in toad bladder epithelia.
- Interaction of ouabain with the Na+ pump in intact epithelial cells.
- Characterization of (8-lysine) vasopressin binding sites on a pig kidney cell line (LLC-PK1). Evidence for hormone-induced receptor transition.
- Parathyroid hormone modulates protein kinase in giant cell tumors of human bone.
- Modulation of cyclic AMP-dependent protein kinase by vasopressin and calcitonin in cultured porcine renal LLC-PK1 cells.
- Relationship of (8-lysine) vasopressin receptor transition to receptor functional properties in a pig kidney cell line (LLC-PK1).
- Contraction of cultured rat glomerular cells of apparent mesangial origin after stimulation with angiotensin II and arginine vasopressin.
- Cellular accumulation of L-lysine in rat kidney cortex in vivo.
- Localization of physiological receptor sites for aldosteone in the bladder of the toad, Bufo marinus.
- Evidence for vasopressin activation of adenylate cyclase by subunit dissociation.
- Radiation inactivation of multimeric enzymes: application to subunit interactions of adenylate cyclase.
- Radiation inactivation studies of renal brush border water and urea transport.
- Mechanisms of nonhormonal activation of adenylate cyclase based on target analysis.
- Endosomes from kidney collecting tubule cells contain the vasopressin-sensitive water channel.
- Membrane and microfilament organization and vasopressin action in transporting epithelia.
- The cell biology of Heymann nephritis: a model of human membranous glomerulonephritis.
- Vasopressin-sensitive adenylate cyclase: subunit interactions assessed by target analysis and computer modelling.
- Vasopressin-induced changes in the three-dimensional structure of toad bladder apical surface.
- Cross talk between stimulatory and inhibitory guanosine 5'-triphosphate binding proteins: role in activation and desensitization of the adenylate cyclase response to v...
- Effects of hypertonicity on cAMP production in cultured renal epithelial cells (LLC-PK1).
- Target molecular weights for red cell band 3 stilbene and mercurial binding sites.
- Vasopressin receptor-adenylate cyclase interactions. Studies in an intact cultured renal epithelial cell line (LLC-PK1).
- Atrial natriuretic factor and cGMP inhibit amiloride-sensitive Na+ transport in the cultured renal epithelial cell line, LLC-PK1.
- Target analysis studies of red cell water and urea transport.
- Inhibition of epithelial Na+ transport by atriopeptin, protein kinase c, and pertussis toxin.
- Vasopressin signaling in kidney cells.
- Atrial natriuretic peptide regulates release of Na+-K+-ATPase inhibitor from rat brain.
- Renal epithelial cell growth can occur in absence of Na+-H+ exchanger activity.
- Symposium on signal transduction.
- A heterotrimeric G protein, G alpha i-3, on Golgi membranes regulates the secretion of a heparan sulfate proteoglycan in LLC-PK1 epithelial cells.
- Regulation of the G-protein alpha i-2 subunit gene in LLC-PK1 renal cells and isolation of porcine genomic clones encoding the gene promoter.
- Endocytosis of water channels in rat kidney: cell specificity and correlation with in vivo antidiuresis.
- Endocytic vesicles from renal papilla which retrieve the vasopressin-sensitive water channel do not contain a functional H+ ATPase.
- Membrane localization of the pertussis toxin-sensitive G-protein subunits alpha i-2 and alpha i-3 and expression of a metallothionein-alpha i-2 fusion gene in LLC-PK1 ...
- FITC-dextran as a probe for endosome function and localization in kidney.
- Actin filaments regulate epithelial Na+ channel activity.
- Guanine nucleotide binding proteins regulate epithelial Na+ channels.
- Apical endosomes isolated from kidney collecting duct principal cells lack subunits of the proton pumping ATPase.
- Purified epithelial Na+ channel complex contains the pertussis toxin-sensitive G alpha i-3 protein.
- Proteinases inhibit H(+)-ATPase and Na+/H+ exchange but not water transport in apical and endosomal membranes from rat proximal tubule.
- Localization of the CHIP28 water channel in rat kidney.
- Localization of [3H]ouabain-sensitive Na+ pump sites in cultured pig kidney cells.
- A cell strain cultured from porcine kidney increases cyclic AMP content upon exposure to calcitonin or vasopressin.
- Functional water channels are present in clathrin-coated vesicles from bovine kidney but not from brain.
- G protein subunit, alpha i-3, activates a pertussis toxin-sensitive Na+ channel from the epithelial cell line, A6.
Schools
University Of Pennsylvania School Of Medicine
Massachusetts General Hospital
Mass Genl Hospital
NIH
Doctors Specialties
- Nephrology
Accepted Insurances
Awards
- Fellow (FACP)
- Elected Member
- Super Doctor
Education
-
Massachusetts General Hospital -
Perelman School of Medicine at the University of Pennsylvania
Hospital
-
Massachusetts General Hospital
Helpful Reviews
Similar Doctors
|
|
Dr. Julian L. Seifter, MD
 This Doctor is OpenDoctor Recommended.
|
|
|
Nathan E. Hellman |
|
|
Dr. Adina S. Voiculescu, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Andrew M. Siedlecki Jr., MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Robert S. Brown, MD |
|
|
Dr. Michael N. Gottlieb, MD
This Doctor is OpenDoctor Recommended.
|
|
|
Dr. Dena E. Rifkin, MD |
|
|
Dr. Eva B. Long, MD |