Physician
Pulmonology
Dr. Deborah A. Quinn, MD
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Deborah A. Quinn, MD works in the field of Pulmonology. She graduated from University of Massachusetts Medical School. University of Massachusetts Medical School is ranked 49/12 in Research/PrimaryCare. Deborah A. Quinn, MD has written publications. She has 66 publications published with PubMed. The lastest publication is: 'Effect of dimethyl amiloride on chronic hypoxic pulmonary hypertension in rats.' Dr. Deborah A. Quinn is registered with Medicare.
Publications
- Heparin Inhibits Pulmonary Artery Smooth Muscle Cell Proliferation through Guanine Nucleotide Exchange Factor-H1/RhoA/Rho Kinase/p27.
- TLR4 through IFN-β promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
- TLR4 is a negative regulator in noninfectious Lung inflammation.
- Role for nuclear factor-kappaB in augmented Lung injury because of interaction between hyperoxia and high stretch ventilation.
- Inhibition of HA synthase 3 mRNA expression, with a phosphodiesterase 3 inhibitor, blocks Lung injury in a septic ventilated rat model.
- Cyclic stretch affects Pulmonary endothelial cell control of Pulmonary smooth muscle cell growth.
- Deficiency of the NHE1 gene prevents hypoxia-induced Pulmonary hypertension and vascular remodeling.
- Low-molecular-weight heparin inhibits hypoxic Pulmonary hypertension and vascular remodeling in guinea pigs.
- Usefulness of multidetector spiral computed tomography according to age and gender for diagnosis of acute Pulmonary embolism.
- Inhibition of JNK activation prolongs survival after smoke inhalation from fires.
- Gene expression of cyclin-dependent kinase inhibitors and effect of heparin on their expression in mice with hypoxia-induced Pulmonary hypertension.
- Regulation of Lung injury and repair by Toll-like receptors and hyaluronan.
- Cyclin-dependent kinase inhibitor p27Kip1, but not p21WAF1/Cip1, is required for inhibition of hypoxia-induced Pulmonary hypertension and remodeling by heparin in mice.
- Ventilation-induced neutrophil infiltration and apoptosis depend on apoptosis signal-regulated kinase 1 pathway.
- The role of hyaluronan synthase 3 in ventilator-induced Lung injury.
- Ventilation-induced neutrophil infiltration depends on c-Jun N-terminal kinase.
- Low molecular weight hyaluronan from stretched Lung enhances interleukin-8 expression.
- Stretch-induced IL-8 depends on c-Jun NH2-terminal and nuclear factor-kappaB-inducing kinases.
- Systemic microvascular leak in an in vivo rat model of ventilator-induced Lung injury.
- Heparin inhibits SMC growth in the presence of human and fetal bovine serum.
- Interactions of Lung stretch, hyperoxia, and MIP-2 production in ventilator-induced Lung injury.
- Acute renal impairment after immersion and near-drowning.
- A randomized, prospective clinical trial to assess the potential infection risk associated with the PosiFlow needleless connector.
- What progress has been made in meeting the needs of seriously maltreated children? The course of 200 cases through the Boston Juvenile Court.
- What happens after the care and protection petition? Reabuse in a court sample.
- Serious child mistreatment in Massachusetts: the course of 206 children through the courts.
- Substance abuse and serious child mistreatment: prevalence, risk, and outcome in a court sample.
- Diagnosed intellectual and emotional impairment among parents who seriously mistreat their children: prevalence, type, and outcome in a court sample.
- Placement outcomes of 206 severely maltreated children in the Boston Juvenile Court system: a 7.5-year follow-up study.
- Adverse interaction between warfarin and indomethacin.
- The changing radiographic presentation of bronchogenic carcinoma with reference to cell types.
- Blockade of nitric oxide synthesis reduces myocardial oxygen consumption in vivo.
- Protecting severely abused and neglected children. An unkept promise.
- Differential effect of three commercial heparins on Na+/H+ exchange and growth of PASMC.
- Gene 33/Mig-6, a transcriptionally inducible adapter protein that binds GTP-Cdc42 and activates SAPK/JNK. A potential marker transcript for chronic pathologic conditio...
- Contribution of Na+/H+ exchange to pH regulation in Pulmonary artery smooth muscle cells.
- A prospective investigation of Pulmonary embolism in women and men.
- Na+/H+ exchange in Pulmonary artery smooth muscle from spontaneously hypertensive and Wistar-Kyoto rats.
- Smoke aldehyde component influences Pulmonary edema.
- Intravenous injection of propylene glycol causes Pulmonary hypertension in sheep.
- Combined smoke inhalation and scald burn in the rat.
- Bronchial artery ligation modifies Pulmonary edema after exposure to smoke with acrolein.
- Aquaporin channels may modulate ventilator-induced Lung injury.
- Effect of dimethyl amiloride on chronic hypoxic Pulmonary hypertension in rats.
- Role of sulfidopeptide leukotrienes in synthetic smoke inhalation injury in sheep.
- Amiloride analogs inhibit chronic hypoxic Pulmonary hypertension.
- The role of Na+/H+ exchange and growth factors in Pulmonary artery smooth muscle cell proliferation.
- Stretch-induced mitogen-activated protein kinase activation and interleukin-8 production in type II alveolar cells.
- D-dimers in the diagnosis of Pulmonary embolism.
- Heparin oligosaccharide sequence and size essential for inhibition of Pulmonary artery smooth muscle cell proliferation.
- Diagnostic pathways in acute Pulmonary embolism: recommendations of the PIOPED II Investigators.
- Multidetector computed tomography for acute Pulmonary embolism.
- Intracellular glutathione in stretch-induced cytokine release from alveolar type-2 like cells.
- Hyperoxia increases ventilator-induced Lung injury via mitogen-activated protein kinases: a prospective, controlled animal experiment.
- The role of phosphodiesterase 3 in endotoxin-induced acute kidney injury.
- Serine/threonine kinase-protein kinase B and extracellular signal-regulated kinase regulate ventilator-induced pulmonary fibrosis after bleomycin-induced acute Lung in...
- High-molecular-weight hyaluronan--a possible new treatment for sepsis-induced Lung injury: a preclinical study in mechanically ventilated rats.
- Atelectasis induced by thoracotomy causes Lung injury during mechanical ventilation in endotoxemic rats.
- Oxidant stress mediates inflammation and apoptosis in ventilator-induced Lung injury.
- Involvement of Akt and endothelial nitric oxide synthase in ventilation-induced neutrophil infiltration: a prospective, controlled animal experiment.
- Unfractionated heparin and enoxaparin reduce high-stretch ventilation augmented Lung injury: a prospective, controlled animal experiment.
- Thrombospondin-1 null mice are resistant to hypoxia-induced Pulmonary hypertension.
- High MW hyaluronan inhibits smoke inhalation-induced Lung injury and improves survival.
- Low molecular weight hyaluronan, via AP-1 and NF-κB signalling, induces IL-8 in transformed bronchial epithelial cells.
- JNK activation is responsible for mucus overproduction in smoke inhalation injury.
Schools
University of Massachusetts Worcester Campus
Mass Gen Hospital
Conditions Treated
- Lung Cancer
- Pulmonary Hypertension
- Sarcoidosis
- Sleep Apnea
Doctors Specialties
- Critical Care Medicine
- Pulmonology
Accepted Insurances
Education
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Massachusetts General Hospital -
University of Massachusetts Medical School
Hospital
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Massachusetts General Hospital
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