Chief Architect, ASAM's CONTINUUM(TM); Scientific Advisor, Treatment Research Institute
Psychiatry
Dr. David R. Gastfriend, MD
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David R. Gastfriend is an expert in the field of Psychiatry. He researched medicine at Jefferson Medical College. David R. Gastfriend is a published doctor and has 88 publications published. The lastest was: 'Cocaine decreases cortical cerebral blood flow but does not obscure regional activation in functional magnetic resonance imaging in human subjects.'
Publications
- Extended-release naltrexone for alcohol and opioid dependence: A meta-analysis of healthcare utilization studies.
- Opioid challenge evaluation of blockade by extended-release naltrexone in opioid-abusing adults: Dose-effects and time-course.
- Alcohol dependence treatments: comprehensive healthcare costs, utilization outcomes, and pharmacotherapy persistence.
- Cost and utilization outcomes of opioid-dependence treatments.
- Efficacy of Extended-Release Naltrexone in Patients with Relatively Higher Severity of Alcohol Dependence.
- Advancing performance measures for use of medications in substance abuse treatment.
- Intramuscular extended-release naltrexone: current evidence.
- Impact of treatment with intramuscular, injectable, extended-release naltrexone on counseling and support group participation in patients with alcohol dependence.
- Comparison of healthcare utilization among patients treated with alcoholism medications.
- Overriding the blockade of antinociceptive actions of opioids in rats treated with extended-release naltrexone.
- Early treatment response in alcohol dependence with extended-release naltrexone.
- Efficacy of extended-release naltrexone in alcohol-dependent patients who are abstinent before treatment.
- Reduction in heavy drinking as a treatment outcome in alcohol dependence.
- No-Show for Treatment in Substance Abuse Patients with Comorbid Symptomatology: Validity Results from a Controlled Trial of the ASAM Patient Placement Criteria.
- Advances in the pharmacotherapy of alcoholism: challenging misconceptions.
- Developing a baseline assessment battery: balancing patient time burden with essential clinical and research monitoring.
- Factorial designs in clinical trials: options for combination treatment studies.
- Design and analysis of trials of combination therapies.
- Physician substance abuse and recovery: what does it mean for physicians--and everyone else?
- Decreased absolute amygdala volume in cocaine addicts.
- Validation of the Addiction Severity Index (ASI) for internet and automated telephone self-report administration.
- The relationship between cocaine craving, psychosocial treatment, and subsequent cocaine use.
- The ASAM patient placement criteria: context, concepts and continuing development.
- Determining service variations between and within ASAM levels of care.
- Reliability of multidimensional substance abuse treatment matching: implementing the ASAM Patient Placement Criteria.
- Predictive validity of the ASAM Patient Placement Criteria for hospital utilization.
- New constructs and assessments for relapse and continued use potential in the ASAM Patient Placement Criteria.
- Visual inspection of medications in preventing unexplained relapses.
- Cocaine-primed craving and its relationship to depressive symptomatology in individuals with cocaine dependence.
- Retention in psychosocial treatment of cocaine dependence: predictors and impact on outcome.
- Addiction denial and cognitive dysfunction: a preliminary investigation.
- Long-term opioid blockade and hedonic response: preliminary data from two open-label extension studies with extended-release naltrexone.
- Injectable extended-release naltrexone for opioid dependence: a double-blind, placebo-controlled, multicentre randomised trial.
- Combined pharmacotherapies and behavioral interventions for alcohol dependence: the COMBINE study: a randomized controlled trial.
- Prevalence of physical and sexual abuse among substance abuse patients and impact on treatment outcomes.
- The effect of 12-step self-help group attendance and participation on drug use outcomes among cocaine-dependent patients.
- Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial.
- Effects of naltrexone treatment for alcohol-related disorders on healthcare costs in an insured population.
- Effect of extended-release naltrexone (XR-NTX) on quality of life in alcohol-dependent patients.
- Persistence with oral naltrexone for alcohol treatment: implications for health-care utilization.
- HIV risk reduction in the National Institute on Drug Abuse Cocaine Collaborative Treatment Study.
- Establishing the feasibility of performance measures for alcohol and other drugs.
- Olanzapine-induced hyperventilation: case report.
- A multi-site dose ranging study of nalmefene in the treatment of alcohol dependence.
- Comorbidity, smoking behavior and treatment outcome.
- Substance user treatment program quality: selected topics.
- The Boston Target Cities program: overview and evaluation results.
- Cocaine decreases cortical cerebral blood flow but does not obscure regional activation in functional magnetic resonance imaging in human subjects.
- Cardiovascular effects of desipramine in children and adolescents with attention deficit disorder.
- Who starts treatment: engagement in the NIDA collaborative cocaine treatment study.
- Impact of psychosocial treatments on associated problems of cocaine-dependent patients.
- Patient placement criteria and their relation to access to appropriate level of care and engagement in alcoholism treatment.
- Gender differences in cocaine craving among non-treatment-seeking individuals with cocaine dependence.
- Clinical outcomes following cocaine infusion in nontreatment-seeking individuals with cocaine dependence.
- Placement matching: challenges and technical progress.
- Ultrarapid opioid detoxification: effects on cardiopulmonary physiology, stress hormones and clinical outcomes.
- Predictors of self-help group attendance in cocaine dependent patients.
- The validity of self-reported drug use in non-treatment seeking individuals with cocaine dependence: correlation with biochemical assays.
- Desipramine in the treatment of attention deficit disorder in adolescents.
- Use of haloperidol in the management of agitated or violent, alcohol-intoxicated patients in the emergency department: a pilot study.
- Desipramine in the treatment of children with attention deficit disorder.
- Microcomputer database management systems concepts.
- Orthostatic hypotension and antidepressant pharmacotherapy.
- An Intelligent Display System for psychiatric education in primary care.
- Adjunct low dose lithium carbonate in treatment-resistant depression: a placebo-controlled study.
- Acute distress after switch from Norpramin to generic desipramine.
- Adjunctive buspirone in benzodiazepine treatment of four patients with panic disorder.
- Postcardiotomy delirium: a critical review.
- The Addiction Severity Index as a screen for trauma and posttraumatic stress disorder.
- Cocaine dependence with and without PTSD among subjects in the National Institute on Drug Abuse Collaborative Cocaine Treatment Study.
- Buprenorphine treatment of opiate and cocaine abuse: clinical and preclinical studies.
- Acute effects of cocaine on human brain activity and emotion.
- The National Institute on Drug Abuse Collaborative Cocaine Treatment Study. Rationale and methods.
- Treatment matching. Theoretic basis and practical implications.
- The effect of anonymous vs. nonanonymous rating conditions on patient satisfaction and motivation ratings in a population of substance abuse patients.
- A measure of readiness for substance abuse treatment. Psychometric properties of the RAATE-R interview.
- A pilot study of factors associated with resilience to substance abuse in adolescent sons of alcoholic fathers.
- Pharmacotherapy of psychiatric syndromes with comorbid chemical dependence.
- Buprenorphine effects on morphine- and cocaine-induced subjective responses by drug-dependent men.
- Nitric oxide-induced motor neuron disease in a patient with alcoholism.
- The glutamatergic basis of human alcoholism.
- Desipramine in the treatment of adolescents with attention deficit disorder.
- Depressive symptomatology and cocaine-induced pituitary-adrenal axis activation in individuals with cocaine dependence.
- Feasibility of multidimensional substance abuse treatment matching: automating the ASAM Patient Placement Criteria. American Society of Addiction Medicine.
- Psychosocial treatments for cocaine dependence: National Institute on Drug Abuse Collaborative Cocaine Treatment Study.
- Self-help group attendance and participation among cocaine dependent patients.
- The Addiction Severity Index: a field study of internal consistency and validity.
Schools
Thomas Jefferson University
Presby University Penn Med Center
Massachusetts General Hospital
Doctors Specialties
- Addiction Psychiatry
- Psychiatry
Accepted Insurances
Education
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Massachusetts General Hospital -
University of Pennsylvania -
Jefferson Medical College
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