Professor, Pathology, University of Arizona College of Medicine

Pathology

Dr. Daphne E. Demello, MD

Daphne E. Demello is an expert in the field of Pathology. She graduated from Seth G.S. Medical College. Daphne Demello is also a published doctor. She has 101 paper published. The most recent paper is: Mesenteric Castleman's disease masquerading as inflammatory bowel disease.

Publications

Pulmonary pathology in thyroid transcription factor-1 deficiency syndrome.
Tumor necrosis factor-alpha from macrophages enhances LPS-induced clara cell expression of keratinocyte-derived chemokine.
Clara cells impact the pulmonary innate immune response to LPS.
Molecular mechanisms of pulmonary vascular development.
Pediatric CD56+ anaplastic large cell lymphoma: a review of the literature.
Development of vaccines and passive immunotherapy against SARS coronavirus using mouse and SCID-PBL/hu mouse models.
Severe bilateral panlobular emphysema and pulmonary arterial hypoplasia: unusual manifestations of Menkes disease.
Primary type II alveolar epithelial cells present microbial antigens to antigen-specific CD4+ T cells.
A novel inflammation-induced ubiquitin E3 ligase in alveolar type II cells.
Defective pulmonary development in the absence of heparin-binding vascular endothelial growth factor isoforms.
Generation and characterization of a conditionally immortalized lung clara cell line from the H-2Kb-tsA58 transgenic mouse.
Infantile cardiac fibromatosis: correlation of antemortem and necropsy findings.
Transplacental stimulation of functional and morphologic fetal rabbit lung maturation: effect of thyrotropin-releasing hormone.
Both human SP-A1 and Sp-A2 genes are expressed in small and large intestine.
Pericarditis as presenting manifestation of acute nonlymphocytic leukemia in a young child.
Disseminated zygomycosis in a newborn.
Multicystic hepatic mesenchymal hamartoma of childhood. Computerized tomography and ultrasound characteristics.
Expression of genes involved in placental glucose uptake and transport in the nonobese diabetic mouse pregnancy.
Experimental ureteral obstruction in the fetal opossum: histologic assessment.
Ontogeny of type I procollagen expression during human fetal lung development.
Congenital alveolar proteinosis caused by a novel mutation of the surfactant protein B gene and misalignment of lung vessels in consanguineous kindred infants.
Childhood embryonal carcinoma of testis, report of two unusual cases, and the implication on clinical management.
Fetal nephrotoxicity.
Administration of chronic intravenous platelet-activating factor induces pulmonary arterial atrophy and hypertension in rabbits.
GLUT 1-glucose transporter protein in adult and fetal mouse lung.
Growth and development of lungs in siblings with nonimmune hydrops.
Congenital bronchopulmonary malformations. Diagnostic and therapeutic considerations.
Malignant rhabdoid tumor of the thoracic spine. Case report.
Transplacental stimulation of fetal lung maturation: effect of triiodothyronine in the female and male rabbit fetus.
Renal and extrarenal rhabdoid tumors in children: a clinicopathologic study of 14 patients.
Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) presenting with skeletal lesions.
Spontaneous resolution of myelodysplastic cytogenetic abnormality developed during the treatment of leukemia.
Early onset of pulmonary parenchymal disease associated with juvenile rheumatoid arthritis.
The effect of intrauterine growth restriction upon fetal and postnatal hepatic glucose transporter and glucokinase proteins.
Thyrotropin-releasing hormone accelerates fetal mouse lung ultrastructural maturation via stimulation of extra thyroidal pathway.
Early fetal development of lung vasculature.
Congenital alveolar proteinosis in the Netherlands: a report of five cases with immunohistochemical and genetic studies on surfactant apoproteins.
Lung transplantation for treatment of infants with surfactant protein B deficiency.
Propylthiouracil-induced fulminant hepatitis: case report and review of the literature.
Effect of genotype on the levels of surfactant protein A mRNA and on the SP-A2 splice variants in adult humans.
Cell-specific localization of glucose transporter proteins in mammalian lung.
Fetal mouse lung ultrastructural maturation is accelerated by maternal thyrotropin-releasing hormone treatment.
Immunogold localization of SP-A in lungs of infants dying from respiratory distress syndrome.
Effect of maternal diabetes on the expression of genes regulating fetal brain glucose uptake.
Human surfactant protein-C: genetic homogeneity and expression in RDS; comparison with other species.
A mutation in the surfactant protein B gene responsible for fatal neonatal respiratory disease in multiple kindreds.
Surfactant protein B deficiency: antenatal diagnosis and prospective treatment with surfactant replacement.
Ultrastructure of lung in surfactant protein B deficiency.
Molecular and phenotypic variability in the congenital alveolar proteinosis syndrome associated with inherited surfactant protein B deficiency.
Chronic platelet-activating factor induces a decrease in pulmonary vascular compliance, hydroxyproline, and loss of vascular matrix.
Hyperoxia induces interstitial (type I) and increases type IV collagenase mRNA expression and increases type I and IV collagenolytic activity in newborn rat lung.
Primary peritoneal, omental, and mesenteric tumors in childhood.
Myofibrillar degeneration and necrosis of the visceral smooth musculature: an ischemic visceral myopathy.
Absence of tubular myelin in lungs of infants dying with hyaline membrane disease.
Effects of indomethacin in utero on the pulmonary vasculature of the newborn guinea pig.
Cardiac localization of eosinophil-granule major basic protein in acute necrotizing myocarditis.
Detection of lung rejection with indium-111-labeled lymphocytes in heterotopic rat heart-lung transplantation.
Effect of maternal administration of thyrotropin-releasing hormone or DN1417 on functional and morphologic fetal rabbit lung maturation and duration of survival after ...
The utility of postmortem lung for RNA studies; variability and correlation of the expression of surfactant proteins in human lung.
Tropoelastin gene expression in the rat pulmonary vasculature: a developmental study.
Acute hepatic failure in severe iron poisoning.
Diagnostic value of histochemistry in embryonal rhabdomyosarcoma.
Mesenteric Castleman's disease masquerading as inflammatory bowel disease.
Computerized morphometry of the pulmonary vasculature over a range of intravascular pressures.
An SP-B gene mutation responsible for SP-B deficiency in fatal congenital alveolar proteinosis: evidence for a mutation hotspot in exon 4.
Delayed ultrastructural lung maturation in the fetal and newborn hypothyroid (Hyt/Hyt) mouse.
Pathophysiology and treatment of surfactant protein-B deficiency.
Partial deficiency of surfactant protein B in an infant with chronic lung disease.
Ethmoidal fibro-osseous lesion in a child. Diagnostic and therapeutic problems.
Budd--Chiari syndrome in a child.
Heterotopic growth of dysplastic cerebellum in frontal encephalocele in an infant of a diabetic mother.
Infantile hypoventilation syndrome, neurenteric cyst, and syringobulbia.
Omental-mesenteric myxoid hamartomas. Infantile lesions simulating malignant tumors.
Prolonged elevation of transaminase concentration in children with unsuspected myopathy.
Takayasu's disease with aneurysm of right common iliac artery and iliocaval fistula in a young infant: case report and review of the literature.
Histopathology of nodular renal blastema.
Midline cervical cysts in children. Thyroglossal anomalies.
Recurring digital fibroma of childhood.
Immunolocalization of CC10 in Clara cells in mouse and human lung.
Focal congenital alveolar proteinosis associated with abnormal surfactant protein B messenger RNA.
Differential expression of VEGF isoforms in mouse during development and in the adult.
Generation of an immortal differentiated lung type-II epithelial cell line from the adult H-2K(b)tsA58 transgenic mouse.
Embryonic and early fetal development of human lung vasculature and its functional implications.
Aberrant SP-B mRNA in lung tissue of patients with congenital alveolar proteinosis (CAP).
Population-based estimates of surfactant protein B deficiency.
An alternatively spliced surfactant protein B mRNA in normal human lung: disease implication.
Atelectasis--an unusual and late complication of lung transplant.
Pulmonary alveolar proteinosis: a review.
Expression of the 35kDa and low molecular weight surfactant-associated proteins in the lungs of infants dying with respiratory distress syndrome.
Diffusible signal to murine alveolar macrophages from lipopolysaccharide- and Escherichia coli-stimulated lung Type II epithelial cells.
Persistent right valve of the sinus venosus presenting as a right atrial cystic mass.
Unsuspected transection of lung by pigtail catheter in a premature infant.
Morphologic changes in alveolar macrophages in response to UVEC-activated pulmonary Type II epithelial cells.
Comparison of surfactant protein B polymorphisms of healthy term newborns with preterm newborns having respiratory distress syndrome.
Clara cell adhesion and migration to extracellular matrix.
Toll-like receptor 4-deficient mice are resistant to chronic hypoxia-induced pulmonary hypertension.
Distal airways in mice exposed to cigarette smoke: Nrf2-regulated genes are increased in Clara cells.
Comparison of angioplasty and surgery for neonatal aortic coarctation.
Pulmonary pathology.
Neonatal orchitis mimicking cystic dysplasia of the testis.

Doctors Specialties

Pediatric Pathology
Pathology

Accepted Insurances

Education

Seth G.S. Medical College

Hospital

Phoenix Children's Hospital

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