Professor, Pathology, Ohio State University College of Medicine
Pathology
Dr. Daniel D. Sedmak, MD
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Daniel Sedmak is an expert in the field of Pathology. He went to The Ohio State University College of Medicine. He over the years received 1 awards: "Top MD". Daniel D. Sedmak, MD is a published doctor and has 101 publications published. The lastest was: 'Clinical implications of the diagnosis of renal allograft infarction by percutaneous biopsy.'
Publications
- Personalized healthcare in clotting disorders.
- Lipopolysaccharide, tumor necrosis factor alpha, or interleukin-1beta triggers reactivation of latent cytomegalovirus in immunocompetent mice.
- Pulmonary cytomegalovirus reactivation causes pathology in immunocompetent mice.
- Human cytomegalovirus protein pp71 disrupts major histocompatibility complex class I cell surface expression.
- The association of prior cytomegalovirus infection with neovascular age-related macular degeneration.
- Analysis of the molecular quality of human tissues: an experience from the Cooperative Human Tissue Network.
- The expression of the cytomegalovirus chemokine receptor homolog US28 sequesters biologically active CC chemokines and alters IL-8 production.
- Human cytomegalovirus disrupts constitutive MHC class II expression.
- Intra-abdominal bacterial infection reactivates latent pulmonary cytomegalovirus in immunocompetent mice.
- Elephants in academic medicine.
- Do deans and teaching hospital CEOs agree on what it takes to be a successful clinical department chair?
- Rock stars in academic medicine.
- Staphylococcus infection-associated glomerulonephritis mimicking IgA nephropathy.
- Antisense transcription in the human cytomegalovirus transcriptome.
- Effect of fixatives and tissue processing on the content and integrity of nucleic acids.
- Relative merits of the avidin-biotin complex (ABC) and unlabeled peroxidase-antiperoxidase technics for studying polypeptide hormones.
- Modification of xenograft hyperacute rejection via xenoantibody depletion.
- Pulmonary-renal syndrome in a patient with fibrillary glomerulonephritis.
- Renal autotransplantation in the loin pain-hematuria syndrome: a cautionary note.
- Measurement of SC5b-9 in urine in patients with the nephrotic syndrome.
- Myelination in chronically-alcoholic mice.
- Peritubular capillary C4d staining in late acute renal allograft rejection--is it relevant?
- Parvovirus B19 associated adult Henoch Schönlein purpura.
- Cytomegalovirus and transcriptional down-regulation of major histocompatibility complex class II expression.
- Microsphere-adenoviral complexes target and transduce the glomerulus in vivo.
- Proximal tubular epithelial hyperplasia in patients with chronic glomerular proteinuria.
- Cytomegalovirus induces sialyl Lewis(x) and Lewis(x) on human endothelial cells.
- Recurrent type I membranoproliferative glomerulonephritis in a renal allograft: successful treatment with plasmapheresis.
- Human cytomegalovirus blocks interferon-gamma stimulated up-regulation of major histocompatibility complex class I expression and the class I antigen processing machi...
- Attenuation of cytomegalovirus-induced endothelial intercellular adhesion molecule-1 mRNA/protein expression and T lymphocyte adhesion by a 2'-O-methoxyethyl antisense...
- Inhibition of cytomegalovirus in vitro and in vivo by the experimental immunosuppressive agent leflunomide.
- Viral inhibition of interferon signal transduction.
- Cytomegalovirus-mediated modulation of adhesion molecule expression by human arterial and microvascular endothelial cells.
- Renal allograft survival following acute rejection correlates with blood pressure levels and histopathology.
- Novel mechanism of inhibition of cytomegalovirus by the experimental immunosuppressive agent leflunomide.
- Trans vivo analysis of human delayed-type hypersensitivity reactivity.
- Human cytomegalovirus inhibits IFN-alpha-stimulated antiviral and immunoregulatory responses by blocking multiple levels of IFN-alpha signal transduction.
- Pathologic classification of chronic allograft nephropathy: pathogenic and prognostic implications.
- Predictive value of histopathology and function on outcome of renal allografts after acute rejection.
- Viral effects on antigen processing.
- Clinical implications of the diagnosis of renal allograft infarction by percutaneous biopsy.
- Successful DNA transfer in cultured human mesangial cells using replication deficient recombinant adenovirus.
- Human cytomegalovirus inhibits major histocompatibility complex class II expression by disruption of the Jak/Stat pathway.
- Function and survival of renal allografts from the same donor transplanted into kidney-only or kidney-pancreas recipients.
- Rapid-onset diabetic nephropathy in type II diabetes mellitus.
- Concerns regarding the current paradigm for chronic allograft rejection.
- Subacute bacterial endocarditis masquerading as type III essential mixed cryoglobulinemia.
- Morphometric analysis of neointimal formation in murine cardiac grafts: III. Dissociation of intestitial fibrosis from neointimal formation.
- Prevention of acute murine cardiac allograft rejection: anti-CD4 or anti-vascular cell adhesion molecule one monoclonal antibodies block acute rejection but permit per...
- Beta2-microglobulin-deficient mice are resistant to bullous pemphigoid.
- Effect of enalapril therapy on glomerular accumulation of immune complexes and mesangial matrix in experimental glomerulonephritis in the nonhuman primate.
- Morphometric analysis of neointimal formation in murine cardiac allografts: II. Rate and location of lesion development.
- Prevalence of hepatitis C in patients with idiopathic glomerulopathies in native and transplant kidneys.
- Human cytomegalovirus does not induce human leukocyte antigen class II expression on arterial endothelial cells.
- Prolonged murine cardiac allograft acceptance: characteristics of persistent active alloimmunity after treatment with gallium nitrate versus anti-CD4 monoclonal antibody.
- Monocyte chemoattractant protein-1 binding by cytomegalovirus-infected endothelial cells.
- CMV as an exacerbating agent in transplant vascular sclerosis: potential immune-mediated mechanisms modelled in vitro.
- Morphometric analysis of neointimal formation in murine cardiac allografts.
- Apoptosis in murine cardiac grafts.
- The high prevalence of severe early posttransplant renal allograft pathology in hepatitis C positive recipients.
- Isolation from human placenta of the IgG transporter, FcRn, and localization to the syncytiotrophoblast: implications for maternal-fetal antibody transport.
- Progressive histologic injury in kidneys from heart and liver transplant recipients receiving cyclosporine.
- Loin pain-hematuria syndrome associated with thin glomerular basement membrane disease and hemorrhage into renal tubules.
- Endothelial HLA class II induction mediated by allogeneic T cells activated by cytomegalovirus-infected cultured endothelial cells.
- Cellular localization of CD4 in the human placenta. Implications for maternal-to-fetal transmission of HIV.
- Xanthogranulomatous pyelonephritis in renal allografts: report of 2 cases.
- Cytomegalovirus inhibits major histocompatibility class II expression on infected endothelial cells.
- Alloantigenicity of human endothelial cells. IV. Derivation, characterization, and utilization of gonadal vein endothelia to control endothelial alloantigenicity durin...
- Antibody depletion prolongs xenograft survival.
- Effect of recombinant erythropoietin therapy on autoimmunity in systemic lupus erythematosus.
- Association of thin glomerular basement membrane with other glomerulopathies.
- Alloantigenicity of human endothelial cells. III. Quantitated indirect presentation of endothelial alloantigens to human helper T lymphocytes.
- In vitro induction of endothelial HLA class II antigen expression by cytomegalovirus-activated CD4+ T cells.
- Bidirectional transmission of infectious cytomegalovirus between monocytes and vascular endothelial cells: an in vitro model.
- Cytomegalovirus infection is associated with absence of alveolar epithelial cell HLA class II antigen expression.
- Analysis of inflammatory endothelial changes, including VCAM-1 expression, in murine cardiac grafts.
- The role of interferon beta in human cytomegalovirus-mediated inhibition of HLA DR induction on endothelial cells.
- Patterns of inflammatory vascular endothelial changes in murine liver grafts.
- In vitro induction of endothelial adhesion molecule and MHC antigen expression by cytomegalovirus-activated CD4+ T cells.
- Divergent patterns of ELAM-1, ICAM-1, and VCAM-1 expression on cytomegalovirus-infected endothelial cells.
- Immunoglobulin G subclass deficiency and pneumococcal infection after allogeneic bone marrow transplantation.
- Experimental glomerulonephritis induced by antigen that binds to glomerular fibronectin.
- Relationship between leukocytic infiltration and endothelial specialization in murine cardiac allografts.
- Sensitivity and interobserver variability of the Recombigen-HIV-1 LA test.
- Modification of hyperactive xenograft rejection by ex vivo xenoantibody adsorption.
- Inability of cytomegalovirus infection of cultured endothelial cells to induce HLA class II antigen expression.
- Cellular receptors for matrix proteins in normal human kidney and human mesangial cells.
- Vascular endothelial differentiation in sponge matrix allografts.
- Hairy cell leukemia involving an inguinal hernial sac.
- Expression of IgG Fc receptor antigens in placenta and on endothelial cells in humans. An immunohistochemical study.
- Serum C3 levels are diagnostically more sensitive and specific for systemic lupus erythematosus activity than are serum C4 levels. The Lupus Nephritis Collaborative St...
- Preservation of natural endothelial cytopathogenicity of cytomegalovirus by propagation in endothelial cells.
- The role of vascular endothelial cells in transplantation.
- Massive intramuscular myxoma associated with fibrous dysplasia of bone.
- Pulmonary artery dissection induced by a Swan-Ganz catheter.
- Tumorigenicity in athymic mice of the human colon carcinoma cell line SW1116 expressing the tumor-associated antigenic determinant CA 19-9.
- Post-transplantation reticulum-cell sarcoma reclassified as B-cell lymphoma.
- The sensitivity and specificity of monoclonal antibodies URO-2 and 19-9 in the immunohistochemical classification of primary adenocarcinomas.
- Autoimmune oophoritis: a histopathologic study of involved ovaries with immunologic characterization of the mononuclear cell infiltrate.
- The macrophagic origin of multinucleated giant cells in myeloma kidney: an immunohistologic study.
Schools
Ohio State University College of Medicine
Ohio State University College of Medicine Executive Vice Dean
Ohio State University Medical Center Senior Associate Vice President for Health Sciences
Doctors Specialties
- Immunopathology
- Pathology
Accepted Insurances
Awards
- Top MD
Education
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Cleveland Clinic Foundation -
The Ohio State University College of Medicine
Hospital
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Ohio State University Wexner Medical Center
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