Professor of Orthopaedic Surgery, Stanford University
Orthopaedic Surgery
Dr. Constance R. Chu, MD
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Constance R. Chu, MD is an expert in the field of Orthopaedic Surgery. He researched medicine at Harvard Medical School. Harvard Medical School is a top medical university. Harvard Medical School has a rank of 1 in research and a 12 in primary care Constance R. Chu has written publications. He has 67 publications published with PubMed. The lastest paper is: 'The Marshall R. Urist Young Investigator Award. Autogenous flexor tendon grafts. Biologic mechanisms for incorporation.'
Publications
- Short-term Analysis vs Long-term Data on Total Hip Replacement Survivorship.
- The Dance Between Biology, Mechanics, and Structure: A Systems Based Approach to Developing Osteoarthritis Prevention Strategies.
- Effects of high heel wear and increased weight on the Knee during walking.
- A Systems View of Risk Factors for Knee Osteoarthritis Reveals Insights into the Pathogenesis of the Disease.
- Synovial Fluid Lubricant Properties are Transiently Deficient after Arthroscopic Articular Cartilage Defect Repair with Platelet-Enriched Fibrin Alone and with Mesench...
- Quantitative Magnetic Resonance Imaging UTE-T2* Mapping of Cartilage and Meniscus Healing After Anatomic Anterior Cruciate Ligament Reconstruction.
- The Effect of Platelet-Rich Plasma Formulations and Blood Products on Human Synoviocytes: Implications for Intra-articular Injury and Therapy.
- Persistence, Localization, and External Control of Transgene Expression After Single Injection of Adeno-Associated Virus into Injured Joints.
- The Role of ACL Injury in the Development of Posttraumatic Knee Osteoarthritis.
- Registration of Magnetic Resonance Image Series for Knee Articular Cartilage Analysis: Data from the Osteoarthritis Initiative.
- Effects of Doxycycline on Mesenchymal Stem Cell Chondrogenesis and Cartilage Repair.
- The feasibility of randomized controlled trials for early arthritis therapies (Earth) involving acute Anterior cruciate ligament tear cohorts.
- Serum CTXii Correlates With Articular Cartilage Degeneration After Anterior Cruciate Ligament Transection or Arthrotomy Followed by Standardized Exercise.
- Repeatability of ultrashort echo time-based two-component T(2) (*) measurements on cartilages in human Knee at 3 T.
- Early diagnosis to enable early treatment of pre-Osteoarthritis.
- UTE-T2∗ mapping detects sub-clinical meniscus injury after Anterior cruciate ligament tear.
- Novel quantitative imaging for early detection of Joint tissue injury to support early treatment strategies.
- High-resolution ultrashort echo time (UTE) imaging on human Knee with AWSOS sequence at 3.0 T.
- Closing the Gap Between Bench and Bedside Research for Early Arthritis Therapies (EARTH): Report From the AOSSM/NIH U-13 Post-Joint Injury Osteoarthritis Conference II.
- Release of Bioactive Adeno-Associated Virus from Fibrin Scaffolds: Effects of Fibrin Glue Concentrations.
- Arthroscopic optical coherence tomography in diagnosis of early arthritis.
- Multicomponent T2* mapping of Knee cartilage: technical feasibility ex vivo.
- The Clinical Use of Human Culture-Expanded Autologous Bone Marrow Mesenchymal Stem Cells Transplanted on Platelet-Rich Fibrin Glue in the Treatment of Articular Cartil...
- Optical coherence tomography detection of subclinical traumatic cartilage injury.
- Clinical optical coherence tomography of early articular cartilage degeneration in patients with degenerative meniscal Tears.
- Optical coherence tomography grading correlates with MRI T2 mapping and extracellular matrix content.
- Novel multiarm PEG-based hydrogels for tissue engineering.
- In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage.
- Animal models for cartilage regeneration and repair.
- Progressive chondrocyte death after impact injury indicates a need for chondroprotective therapy.
- Sustained hypoxia enhances chondrocyte matrix synthesis.
- Lidocaine potentiates the chondrotoxicity of methylprednisolone.
- Optimizing CO2 normalizes pH and enhances chondrocyte viability during cold storage.
- The 2007 ABC Traveling Fellowship: building international orthopaedic bridges.
- The role of the biochemical and biophysical environment in chondrogenic stem cell differentiation assays and cartilage tissue engineering.
- Lidocaine exhibits dose- and time-dependent cytotoxic effects on bovine articular chondrocytes in vitro.
- Clinical diagnosis of potentially treatable early articular cartilage degeneration using optical coherence tomography.
- Controlled in vivo degradation of genipin crosslinked polyethylene glycol hydrogels within osteochondral defects.
- In vitro exposure to 0.5% bupivacaine is cytotoxic to bovine articular chondrocytes.
- Tonic activation of hypoxia-inducible factor 1alpha in avascular articular cartilage and implications for metabolic homeostasis.
- p38 MAPK and COX2 inhibition modulate human chondrocyte response to TGF-beta.
- Mini-pig fresh osteochondral allografts deteriorate after 1 week of cold storage.
- Arthroscopic microscopy of articular cartilage using optical coherence tomography.
- Recovery of articular cartilage metabolism following thermal stress is facilitated by IGF-1 and JNK inhibitor.
- Hand-held arthroscopic optical coherence tomography for in vivo high-resolution imaging of articular cartilage.
- Recovery of chondrocyte metabolic activity after thermal exposure.
- The Knee pain map: reliability of a method to identify Knee pain location and pattern.
- Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering.
- Adenoviral-mediated transfer of TGF-beta1 but not IGF-1 induces chondrogenic differentiation of human mesenchymal stem cells in pellet cultures.
- Controlled release of bioactive TGF-beta 1 from microspheres embedded within biodegradable hydrogels.
- Analysis of rabbit articular cartilage repair after chondrocyte implantation using optical coherence tomography.
- Assessing degeneration of human articular cartilage with ultra-short echo time (UTE) T2* mapping.
- Donor sex and age influence the chondrogenic potential of human femoral bone marrow stem cells.
- The in vitro effects of bupivacaine on articular chondrocytes.
- Adeno-associated viral gene transfer of transforming growth factor-beta1 to human mesenchymal stem cells improves cartilage repair.
- UTE-T2∗ mapping of human articular cartilage in vivo: a repeatability assessment.
- Single intra-articular injection of adeno-associated virus results in stable and controllable in vivo transgene expression in normal rat Knees.
- The association of osteoarthritis risk factors with localized, regional and diffuse Knee pain.
- In situ assessment of cell viability within biodegradable polylactic acid polymer matrices.
- Articular cartilage transplantation. Clinical results in the Knee.
- Articular cartilage repair using allogeneic perichondrocyte-seeded biodegradable porous polylactic acid (PLA): a tissue-engineering study.
- Osteochondral repair using perichondrial cells. A 1-year study in rabbits.
- The Marshall R. Urist Young Investigator Award. Autogenous flexor tendon grafts. Biologic mechanisms for incorporation.
- Autogenous intrasynovial and extrasynovial tendon grafts: an experimental study of pro alpha 1(I) collagen mRNA expression in dogs.
- Autogenous flexor-tendon grafts. A biomechanical and morphological study in dogs.
- Angiogenesis in healing autogenous flexor-tendon grafts.
Schools
Harvard Medical School
California Orthopaedic Association
Procedures Preformed
- Joint Drainage
- Knee Arthroscopy
- Nerve Block, Somatic
- Non-Spinal Nerve Blocks
Conditions Treated
- Anterior Cruciate Ligament (ACL) or Posterior Cruciate Ligament (PCL) Tear
- Arm Fracture (incl. Elbow and Shoulder)
- Bakers Cyst
- Complications of Joint Prosthesis
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Doctors Specialties
- Orthopedic Surgery
- Orthopaedic Surgery
Accepted Insurances
- Aetna HMO
- Choice Plus POS II
- Blue Card PPO
- Advantage Preferred DirectAccess Plus PPO
- Blue Cross Blue Shield of California PPO
- Select PPO
- Access Plus Savenet
- Basic Exclusive PPO for Small Business
- Basic PPO
- CareSource
- Cigna HMO
- Cigna PPO
- Great West Healthcare-Cigna PPO
- LocalPlus
- Open Access Plus
- Commercial Insurance Company
- CoreSource
- First Health (Coventry Health Care) PPO
- Golden Rule
- Covered California - Bronze PPO
- Health Net PPO
- Individual and Family PPO
- Choice Care PPO
- Medical Mutual of Ohio
- Medicare MCR
- Kaiser PHCS Network PPO
- MultiPlan PPO
- PHCS Network PPO
- Tricare
- Choice Plus POS
- Navigate HMO
- Navigate POS
- Options PPO
- United Healthcare
- UPMC Health Plan
Education
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Harvard Medical School
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