Physician

Neurology

Dr. Claude P. Genain, MD

Claude Genain practices Neurology. He graduated from University of Kentucky College of Medicine. University of Kentucky College of Medicine is ranked 63 in research and 72 in primary care medicine Dr. Claude P. Genain has written publications. He has 61 publications published with PubMed. The lastest publication is: 'Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis.'

Publications

Restrictive and diversifying elements of the anti-myelin/oligodendrocyte glycoprotein antibody response in primate experimental allergic encephalomyelitis.
Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis.
Antibody responses against galactocerebroside are potential stage-specific biomarkers in multiple sclerosis.
Poly(ADP-ribose) polymerase-1 activation in a primate model of multiple sclerosis.
Protein microarrays guide tolerizing DNA vaccine treatment of autoimmune encephalomyelitis.
Approved and future pharmacotherapy for multiple sclerosis.
Molecular characterization of antibody specificities against myelin/oligodendrocyte glycoprotein in autoimmune demyelination.
The human T cell response to myelin oligodendrocyte glycoprotein: a multiple sclerosis family-based study.
Marmoset fine B cell and T cell epitope specificities mapped onto a homology model of the extracellular domain of human myelin oligodendrocyte glycoprotein.
Experimental allergic encephalomyelitis in the New World monkey Callithrix jacchus.
Characterization of the expressed immunoglobulin IGHV repertoire in the New World marmoset Callithrix jacchus.
Frequency, heterogeneity and encephalitogenicity of T cells specific for myelin oligodendrocyte glycoprotein in naive outbred primates.
Cloning, sequencing, and homology analysis of nonhuman primate Fas/Fas-ligand and co-stimulatory molecules.
Treatment of depression is associated with suppression of nonspecific and antigen-specific T(H)1 responses in multiple sclerosis.
Immune responses against the myelin/oligodendrocyte glycoprotein in experimental autoimmune demyelination.
Characterization of the response to myelin basic protein in a non human primate model for multiple sclerosis.
Effective antigen-specific immunotherapy in the marmoset model of multiple sclerosis.
Specific immunotherapy: one size does not fit all.
Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant.
Human nerve growth factor protects common marmosets against autoimmune encephalomyelitis by switching the balance of T helper cell type 1 and 2 cytokines within the ce...
Autoreactivity to myelin antigens: myelin/oligodendrocyte glycoprotein is a prevalent autoantigen.
MR imaging investigations in a non-human primate model of multiple sclerosis.
Demyelination in primate autoimmune encephalomyelitis and acute multiple sclerosis lesions: a case for antigen-specific antibody mediation.
Determinant spreading associated with demyelination in a nonhuman primate model of multiple sclerosis.
Identification of autoantibodies associated with myelin damage in multiple sclerosis.
Inhibition of allergic encephalomyelitis in marmosets by vaccination with recombinant vaccinia virus encoding for myelin basic protein.
Creation of a model for multiple sclerosis in Callithrix jacchus marmosets.
Characterization of the TCRB chain repertoire in the New World monkey Callithrix jacchus.
Late complications of immune deviation therapy in a nonhuman primate.
Antibody facilitation of multiple sclerosis-like lesions in a nonhuman primate.
Active and passively induced experimental autoimmune encephalomyelitis in common marmosets: a new model for multiple sclerosis.
Prevention of autoimmune demyelination in non-human primates by a cAMP-specific phosphodiesterase inhibitor.
In healthy primates, circulating autoreactive T cells mediate autoimmune disease.
Hemodynamics and coronary flow following diltiazem administration in anesthetized dogs and in humans.
Aortic input impedance in normal man and arterial hypertension: its modification during changes in aortic pressure.
Characterization of plasma and cerebrospinal fluid human angiotensinogen and des-angiotensin I-angiotensinogen by direct radioimmunoassay.
Direct radioimmunoassays of renin and renin substrate during converting-enzyme inhibition.
[Changes in angiotensinogen and des-angiotensin I-angiotensinogen in man and rat upon inhibition of converting enzyme].
Distribution of renin activity and angiotensinogen in rat brain. Effects of dietary sodium chloride intake on brain renin.
Failure of salt loading to inhibit tissue norepinephrine turnover in prehypertensive Dahl salt-sensitive rats.
Vignette. Duchenne de Boulogne and the muscle biopsy.
Group C streptococcal meningitis with favorable recovery. A case report.
Separation of brain dolichol kinase from endogenous activating factors: evidence that phospholipid enhances the interaction between enzyme and dolichol.
Activity of a newly identified serine protease in CNS demyelination.
3-D echo planar (1)HMRS imaging in MS: metabolite comparison from supratentorial vs. central brain.
Mechanisms of normal appearing corpus callosum injury related to pericallosal T1 lesions in multiple sclerosis using directional diffusion tensor and 1H MRS imaging.
An open label study of the effects of rituximab in neuromyelitis optica.
Identification of new serum autoantibodies in neuromyelitis optica using protein microarrays.
Complex alternative splicing of the myelin oligodendrocyte glycoprotein gene is unique to human and non-human primates.
The unique impact of changes in normal appearing brain tissue on cognitive dysfunction in secondary progressive multiple sclerosis patients.
Social support as a buffer in the relationship between treatment for depression and T-cell production of interferon gamma in patients with multiple sclerosis.
Synergistic interactions of lipids and myelin basic protein.
Eight-year immunogenicity and safety of interferon beta-1a-Avonex treatment in patients with multiple sclerosis.
Role of lipid interactions in autoimmune demyelination.
Role of nerve growth factor and other trophic factors in brain inflammation.
Frontline: Epitope recognition on the myelin/oligodendrocyte glycoprotein differentially influences disease phenotype and antibody effector functions in autoimmune dem...
Conformational epitopes of myelin oligodendrocyte glycoprotein are targets of potentially pathogenic antibody responses in multiple sclerosis.
Transient increases in anti-aquaporin-4 antibody titers following rituximab treatment in neuromyelitis optica, in association with elevated serum BAFF levels.
Relevant antibody subsets against MOG recognize conformational epitopes exclusively exposed in solid-phase ELISA.
Apoptotic effects of Human Herpesvirus-6A on glia and neurons as potential triggers for central nervous system autoimmunity.

Doctors Specialties

Neurology

Accepted Insurances

Education

University of Kentucky College of Medicine
University of Paris VII Faculty of Medicine

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