Professor, Pathology, Oregon Health and Science University School of Medicine
Pathology
Dr. Christopher L. Corless, MD
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Christopher Corless works in the field of Pathology. He researched medicine at Washington University School of Medicine in St. Louis. He received 2 awards: "CMS Meaningful Use Stage 1 Certification" and "Top MD". Christopher L. Corless, MD is a published MD. He has 98 papers published. The most current publication "A Multiplexed Amplicon Approach for Detecting Gene Fusions by Next-Generation Sequencing." He accepts Medicare payments and is registered with Medicare.gov.
Publications
- A Multiplexed Amplicon Approach for Detecting Gene Fusions by Next-Generation Sequencing.
- Utility of BRAF V600E Mutation-Specific Immunohistochemistry in Detecting BRAF V600E-Mutated Gastrointestinal Stromal Tumors.
- S0502: A SWOG Phase III Randomized Study of Imatinib, With or Without Bevacizumab, in Patients With Untreated Metastatic or Unresectable Gastrointestinal Stromal Tumors.
- Template for Reporting Results of Biomarker Testing of Specimens From Patients With Gastrointestinal Stromal Tumors.
- Crosstalk between KIT and FGFR3 Promotes Gastrointestinal Stromal Tumor Cell Growth and Drug Resistance.
- Novel mutations in neuroendocrine carcinoma of the breast: possible therapeutic targets.
- Assessing copy number alterations in targeted, amplicon-based next-generation sequencing data.
- Elderly Former Smoker with HRAS Mutant Non-Small-Cell Lung Cancer.
- Genetic profiling to determine risk of relapse-free survival in high-risk localized prostate cancer.
- Pathologic and Molecular Features Correlate With Long-Term Outcome After Adjuvant Therapy of Resected Primary GI Stromal Tumor: The ACOSOG Z9001 Trial.
- Hybrid Capture 2 is as Effective as PCR Testing for High-risk Human Papillomavirus in Head and Neck Cancers.
- Gastrointestinal stromal tumors: what do we know now?
- Frequent PIK3CA Mutations in Radial Scars.
- Frequent phosphatidylinositol-3-kinase mutations in proliferative breast lesions.
- Leiomyoma of the Gastrointestinal Tract With Interstitial Cells of Cajal: A Mimic of Gastrointestinal Stromal Tumor.
- Gastrointestinal stromal tumors: molecular markers and genetic subtypes.
- Long-term Results of Adjuvant Imatinib Mesylate in Localized, High-Risk, Primary Gastrointestinal Stromal Tumor: ACOSOG Z9000 (Alliance) Intergroup Phase 2 Trial.
- Novel Method for PIK3CA Mutation Analysis: Locked Nucleic Acid-PCR Sequencing.
- Gene expression of the IGF pathway family distinguishes subsets of gastrointestinal stromal tumors wild type for KIT and PDGFRA.
- PIK3CA-AKT pathway mutations in micropapillary breast carcinoma.
- Combining Highly Multiplexed PCR with Semiconductor-Based Sequencing for Rapid Cancer Genotyping.
- Biphasic Papillary and Lobular Breast Carcinoma With PIK3CA and IDH1 Mutations.
- Human pancreatic cancer fusion 2 (HPC2) 1-B3: A novel monoclonal antibody to screen for pancreatic ductal dysplasia.
- Phosphatidylinositol-3-kinase pathway mutations are common in breast columnar cell lesions.
- Mucinous breast carcinomas lack PIK3CA and AKT1 mutations.
- Multiplex high-throughput gene mutation analysis in acute myeloid leukemia.
- Loss of succinate dehydrogenase subunit B (SDHB) expression is limited to a distinctive subset of gastric wild-type gastrointestinal stromal tumours: a comprehensive g...
- Newly described activating JAK3 mutations in T-cell acute lymphoblastic leukemia.
- Tackling formalin-fixed, paraffin-embedded tumor tissue with next-generation sequencing.
- Medicine. Personalized cancer diagnostics.
- S0356: A Phase II Clinical and Prospective Molecular Trial With Oxaliplatin, Fluorouracil, and External-Beam Radiation Therapy Before Surgery for Patients With Esophag...
- A DNA methylation microarray-based study identifies ERG as a gene commonly methylated in prostate cancer.
- Multiplex Mutation Screening by Mass Spectrometry: Evaluation of 820 Cases from a Personalized Cancer Medicine Registry.
- Phase II, Open-Label, Single-Arm Trial of Imatinib Mesylate in Patients With Metastatic Melanoma Harboring c-Kit Mutation or Amplification.
- Novel biomarker candidates to predict hepatic fibrosis in hepatitis C identified by serum proteomics.
- Large-scale analysis of KIT aberrations in Chinese patients with melanoma.
- "Pediatric-type" gastrointestinal stromal tumors in adults: distinctive histology predicts genotype and clinical behavior.
- Primary Melanoma of the Spinal Cord: A Case Report, Molecular Footprint, and Review of the Literature.
- Immunohistochemical and molecular markers in breast phyllodes tumors.
- Distinctive morphology of renal cell carcinomas in tuberous sclerosis.
- A molecular portrait of gastrointestinal stromal tumors: an integrative analysis of gene expression profiling and high-resolution genomic copy number.
- Phase III study comparing gemcitabine plus cetuximab versus gemcitabine in patients with advanced pancreatic adenocarcinoma: Southwest Oncology Group-directed intergro...
- Primary extragastrointestinal stromal tumor of the pleura: report of a unique case with genetic confirmation.
- Absence of BRAF, NRAS, KRAS, HRAS mutations, and RET/PTC gene rearrangements distinguishes dominant nodules in Hashimoto thyroiditis from papillary thyroid carcinomas.
- Sentinel lymph node staging of cutaneous melanoma: predictors and outcomes.
- High prevalence of PIK3CA/AKT pathway mutations in papillary neoplasms of the breast.
- Resistance to Tyrosine Kinase Inhibitors in Gastrointestinal Stromal Tumors.
- Molecular target modulation, imaging, and clinical evaluation of gastrointestinal stromal tumor patients treated with sunitinib malate after imatinib failure.
- Primary scrotal melanoma presenting as a large, amelanotic, exophytic mass.
- Molecular determinants of response to matuzumab in combination with paclitaxel for patients with advanced non-small cell lung cancer.
- Monoclonal antibody DOG1.1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes.
- Rhabdomyosarcomatous differentiation in gastrointestinal stromal tumors after tyrosine kinase inhibitor therapy: a novel form of tumor progression.
- Dotlike or Golgi-like KIT and PDGFRA Staining in GISTs.
- Imatinib targeting of KIT-mutant oncoprotein in melanoma.
- Primary and secondary kinase genotypes correlate with the biological and clinical activity of sunitinib in imatinib-resistant gastrointestinal stromal tumor.
- Correlation of kinase genotype and clinical outcome in the North American Intergroup Phase III Trial of imatinib mesylate for treatment of advanced gastrointestinal st...
- KIT gene mutations and copy number in melanoma subtypes.
- The value of traditional upper endoscopy as a diagnostic test for Barrett's esophagus.
- Expression analysis of Barrett's esophagus-associated high-grade dysplasia in laser capture microdissected archival tissue.
- Protein kinase A RII-like (R2D2) proteins exhibit differential localization and AKAP interaction.
- Major response to imatinib mesylate in KIT-mutated melanoma.
- Clinicopathologic profile of gastrointestinal stromal tumors (GISTs) with primary KIT exon 13 or exon 17 mutations: a multicenter study on 54 cases.
- A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors.
- Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stro...
- Molecular pathobiology of gastrointestinal stromal sarcomas.
- Primary adenoid cystic carcinoma of the lung: absence of KIT mutations.
- Pediatric KIT wild-type and platelet-derived growth factor receptor alpha-wild-type gastrointestinal stromal tumors share KIT activation but not mechanisms of genetic ...
- Clonal evolution of resistance to imatinib in patients with metastatic gastrointestinal stromal tumors.
- Imatinib in the management of multiple gastrointestinal stromal tumors associated with a germline KIT K642E mutation.
- BRAF in papillary thyroid carcinoma of ovary (struma ovarii).
- Percutaneous vein occlusion with small intestinal submucosa: an experimental pilot study in Swine and sheep.
- Sentinel node staging of primary melanoma by the "10% rule": pathology and clinical outcomes.
- Accuracy of pathologic examination in detection of complete response after chemoradiation for esophageal cancer.
- Assessment of FIBROSpect II to detect hepatic fibrosis in chronic hepatitis C patients.
- TLE1 as a diagnostic immunohistochemical marker for synovial sarcoma emerging from gene expression profiling studies.
- Ménétrier disease and gastrointestinal stromal tumors: hyperproliferative disorders of the stomach.
- Allele-specific polymerase chain reaction for the imatinib-resistant KIT D816V and D816F mutations in mastocytosis and acute myelogenous leukemia.
- Molecular correlates of imatinib resistance in gastrointestinal stromal tumors.
- Effects of blood flow and/or ventilation restriction on radiofrequency coagulation size in the lung: an experimental study in swine.
- Outcome following surgical therapy for gastrointestinal stromal tumors.
- Extragastrointestinal stromal tumors presenting as vulvovaginal/rectovaginal septal masses: a diagnostic pitfall.
- Loss of transforming growth factor-beta type II receptor promotes metastatic head-and-neck squamous cell carcinoma.
- Comparison of the endothelialization of small intestinal submucosa, dacron, and expanded polytetrafluoroethylene suspended in the thoracoabdominal aorta in sheep.
- Clinical and molecular studies of the effect of imatinib on advanced aggressive fibromatosis (desmoid tumor).
- The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase.
- Phase II study of imatinib mesylate in chemotherapy refractory germ cell tumors expressing KIT.
- A landscape effect in tenosynovial giant-cell tumor from activation of CSF1 expression by a translocation in a minority of tumor cells.
- Rare expression of KIT and absence of KIT mutations in high grade renal cell carcinoma.
- Gastrointestinal stromal tumors: insights from a new familial GIST kindred with unusual genetic and pathologic features.
- Experimental percutaneous extrahepatic portacaval shunt creation by transjugular approach in Swine.
- PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib.
- Resistance of prostate cancer cell lines to COX-2 inhibitor treatment.
- Distinct mechanisms of TGF-beta1-mediated epithelial-to-mesenchymal transition and metastasis during skin carcinogenesis.
- Gastric GI stromal tumors (GISTs): the role of surgery in the era of targeted therapy.
- Determination of stromal signatures in breast carcinoma.
- In vivo bioavailability and pharmacokinetics of a c-MYC antisense phosphorodiamidate morpholino oligomer, AVI-4126, in solid tumors.
- Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: Imatinib Target Exploration Consortium Study B2225.
Schools
Washington Center School of Medicine
Doctors Specialties
- Anatomic Pathology
- Pathology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Top MD
Education
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Brigham and Women's Hospital -
Washington University School of Medicine in St. Louis
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1568477065 |
| Last Name Of The Provider | CORLESS |
| First Name Of The Provider | CHRISTOPHER |
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