Professor of Medicine, Medical College Wisc
Hematology
Dr. Christopher Chitambar, MD
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Christopher Chitambar practices Hematology. He studied medicine at Christian Medical College Ludhiana. He has 8 awards "America's Top Doctors", "America's Top Doctors for Cancer", "CMS Meaningful Use Stage 1 Certification", "Redbook Magazine: Top Breast Cancer Doctors", "Fellow (FACP)", "Whos Who in Medicine and Healthcare", "Super Doctor" and "Top MD". Dr. Christopher Chitambar is also published. He has 86 publications published. The lastest publication: "Evaluation of transferrin and gallium-pyridoxal isonicotinoyl hydrazone as potential therapeutic agents to overcome lymphoid leukemic cell resistance to gallium nitrate.' He is registered with Medicare.
Publications
- Gallium Maltolate Inhibits Human Cutaneous T-Cell Lymphoma Tumor Development in Mice.
- Iron-Targeting Antitumor Activity of Gallium Compounds and Novel Insights Into Triapine(®)-Metal Complexes.
- Gallium-containing antiCancer compounds.
- A Phase II Study of Concurrent Docetaxel, Epirubicin and Cyclophosphamide as a Neoadjuvant Chemotherapy Regimen in Patients with Locally Advanced Breast Cancer.
- Cytotoxic Evaluation of 3-Aminopyridine-2-Carboxaldehyde ThiosemicarbaZone, 3-AP, in Peripheral Blood Lymphocytes of Patients with Refractory Solid Tumors using Electr...
- Role of oxidative stress in the induction of metallothionein-2A and heme oxygenase-1 gene expression by the antineoplastic agent gallium nitrate in human lymphoma Cells.
- Electron paramagnetic resonance study of peripheral blood mononuclear Cells from patients with refractory solid tumors treated with Triapine.
- Development of gallium compounds for treatment of lymphoma: gallium maltolate, a novel hydroxypyrone gallium compound, induces apoptosis and circumvents lymphoma Cell ...
- Case reports: efalizumab-associated lymphoproliferative Disease.
- Gene expression analysis of gallium-resistant and gallium-sensitive lymphoma Cells reveals a role for metal-responsive transcription factor-1, metallothionein-2A, and ...
- Expression of the hemochromatosis gene modulates the cytotoxicity of doxorubicin in breast cancer Cells.
- Gallium-induced Cell death in lymphoma: role of transferrin receptor cycling, involvement of Bax and the mitochondria, and effects of proteasome inhibition.
- Resistance to the antineoplastic agent gallium nitrate results in marked alterations in intraCellular iron and gallium trafficking: identification of novel intermediates.
- Cellular iron metabolism: mitochondria in the spotlight.
- Gallium compounds as antineoplastic agents.
- Apoptotic mechanisms of gallium nitrate: basic and clinical investigations.
- Nitric oxide mitigates peroxide-induced iron-signaling, oxidative damage, and apoptosis in endothelial Cells: role of proteasomal function?
- Oxidant-induced iron signaling in Doxorubicin-mediated apoptosis.
- Nitric oxide inhibits H2O2-induced transferrin receptor-dependent apoptosis in endothelial Cells: Role of ubiquitin-proteasome pathway.
- Expression of the hemochromatosis (HFE) gene modulates the Cellular uptake of 67Ga.
- Gallium nitrate revisited.
- Oxidative stress-induced iron signaling is responsible for peroxide-dependent oxidation of dichlorodihydrofluorescein in endothelial Cells: role of transferrin recepto...
- Expression of MUM1/IRF4 correlates with clinical outcome in patients with B-cell chronic lymphocytic Leukemia.
- CD5+ T-Cell/histiocyte-rich large B-Cell lymphoma.
- Genomic imbalances in drug-resistant T-cell Acute lymphoblastic CEM leukemia cell lines.
- Diagnosis, workup, and prognosis of cutaneous metastases of unknown primary origin.
- Transferrin receptor-dependent iron uptake is responsible for doxorubicin-mediated apoptosis in endothelial Cells: role of oxidant-induced iron signaling in apoptosis.
- Medical applications and toxicities of gallium compounds.
- Intravascular large B-Cell lymphoma, an exclusively small vessel disease? A case report and review of literature.
- A novel gallium compound synergistically enhances bortezomib-induced apoptosis in mantle Cell lymphoma Cells.
- Analysis of single nucleotide polymorphism C3435T of the multidrug resistance gene MDR1 in Acute lymphoblastic leukemia.
- Gallium nitrate for the treatment of non-Hodgkin''s Lymphoma.
- Mantle Cell lymphoma in lymph nodes with metastatic small Cell carcinoma of lung: a diagnostic and treatment dilemma.
- A unique collision tumor in breast: invasive ductal Carcinoma and mucosa-associated lymphoid tissue lymphoma.
- Continuous 5-fluorouracil infusion in advanced gastric Carcinoma.
- Continuous 5-fluorouracil (5FU) infusion in Carcinoma of the pancreas: a phase II study.
- The effects of various transferrins on iron utilization by proliferating Cells.
- Partially matched bone marrow transplantation in patients with myelodysplastic Syndromes.
- Inhibition of malignant Cell growth by 311, a novel iron chelator of the pyridoxal isonicotinoyl hydrazone class: effect on the R2 subunit of ribonucleotide reductase.
- Iron transport in a lymphoid Cell line with the hemochromatosis C282Y mutation.
- The anti-malarial artesunate is also active against Cancer.
- Cellular adaptation to down-regulated iron transport into lymphoid leukaemic Cells: effects on the expression of the gene for ribonucleotide reductase.
- Increased sensitivity of hydroxyurea-resistant leukemic Cells to gemcitabine.
- Evaluation of transferrin and gallium-pyridoxal isonicotinoyl hydrazone as potential therapeutic agents to overcome lymphoid leukemic Cell resistance to gallium nitrate.
- Interaction of gallium nitrate with other inhibitors of ribonucleotide reductase: effects on the proliferation of human leukemic Cells.
- Gallium-pyridoxal isonicotinoyl hydraZone (Ga-PIH), a novel cytotoxic gallium complex. A comparative study with gallium nitrate.
- Transferrin receptor-dependent and -independent iron transport in gallium-resistant human lymphoid leukemic Cells.
- Evaluation of continuous-infusion gallium nitrate and hydroxyurea in combination for the treatment of refractory non-Hodgkin's Lymphoma.
- Resistance to the antitumor agent gallium nitrate in human leukemic Cells is associated with decreased gallium/iron uptake, increased activity of iron regulatory prote...
- Effect of gallium nitrate therapy on Ga-67 scintigraphic detection of Lymphoma: case report.
- Modulation of in vitro and in vivo T-Cell responses by transferrin-gallium and gallium nitrate.
- Modulation of transferrin receptor mRNA by transferrin-gallium in human myeloid HL60 and lymphoid CCRF-CEM leukaemic Cells.
- Synergistic inhibition of T-lymphoblastic leukemic CCRF-CEM Cell growth by gallium and recombinant human alpha-interferon through action on Cellular iron uptake.
- Prevention of gallium toxicity by hyperhydration in treatment of medulloblastoma.
- Gallium nitrate delays the progression of microscopic Disease in a human medulloblastoma murine model.
- Induction of apoptosis by iron deprivation in human leukemic CCRF-CEM Cells.
- Effect of hydroxyurea on Cellular iron metabolism in human leukemic CCRF-CEM Cells: changes in iron uptake and the regulation of transferrin receptor and ferritin gene...
- Familial Leukemia and aplastic anemia associated with monosomy 7.
- Regulation of transferrin receptor expression on human leukemic Cells during proliferation and induction of differentiation. Effects of gallium and dimethylsulfoxide.
- Inhibition of hemoglobin proDuction by transferrin-gallium.
- Uptake of gallium-67 by human leukemic Cells: demonstration of transferrin receptor-dependent and transferrin-independent mechanisms.
- Effects of different transferrin forms on transferrin receptor expression, iron uptake, and Cellular proliferation of human leukemic HL60 Cells. Mechanisms responsible...
- Inhibition of leukemic HL60 Cell growth by transferrin-gallium: effects on ribonucleotide reductase and demonstration of drug synergy with hydroxyurea.
- Release of soluble transferrin receptor from the surface of human leukemic HL60 Cells.
- Transferrin receptor-mediated suppression of in vitro hematopoiesis by transferrin-gallium.
- Modulation of lymphocyte proliferation and immunoglobulin proDuction by transferrin-gallium.
- Influence of Cellular iron status on the release of soluble transferrin receptor from human promyelocytic leukemic HL60 Cells.
- Role of the acidic receptosome in the uptake and retention of 67Ga by human leukemic HL60 Cells.
- Successful allogeneic transplantation of T-Cell-depleted bone marrow from closely HLA-matched unrelated donors.
- Development of drug resistance to gallium nitrate through modulation of Cellular iron uptake.
- Differential effects of gallium nitrate on proliferation of brain tumor Cells in vitro.
- Inhibition of ribonucleotide reductase by gallium in murine leukemic L1210 Cells.
- Shedding of transferrin receptor from rat reticulocytes during maturation in vitro: soluble transferrin receptor is derived from receptor shed in vesicles.
- Allogeneic bone marrow transplantation for relapsed and refractory Lymphoma using genotypically HLA-identical and alternative donors.
- Alteration of DNA synthesis in human brain tumor Cells by gallium nitrate in vitro.
- Twice-daily tapering dexamethasone treatment during cranial radiation for newly diagnosed brain metastases.
- Evaluation of continuous infusion low-dose 5-azacytidine in the treatment of myelodysplastic Syndromes.
- Interaction of gallium nitrate with fludarabine and iron chelators: effects on the proliferation of human leukemic HL60 Cells.
- Inhibition of iron uptake in HL60 Cells by 2-formylpyridine monothiosemicarbazonato Cu(II).
- Targeting iron-dependent DNA synthesis with gallium and transferrin-gallium.
- Regulatory effects of gallium on transferrin-independent iron uptake by human leukemic HL60 Cells.
- Aspergillus and aspergillosis.
- Antineoplastic effects of gallium nitrate on human medulloblastoma in vivo.
- Effect of gallium on the tyrosyl radical of the iron-dependent M2 subunit of ribonucleotide reDuctase.
- Pityrosporum folliculitis after bone marrow transplantation. Clinical observations in five patients.
Schools
Christian Medical College Ludhiana Baba Farid University Of Health Sciences
Brackenridge Hospital
University Colo Health Scis Center
Procedures Preformed
- Plasmapheresis
- Thoracentesis
Conditions Treated
- Acute Leukemia
- Anemia
- Antiphospholipid Syndrome (APS)
- Basal Cell Carcinoma
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Doctors Specialties
- Hematology
- Medical Oncology
- Oncology
Accepted Insurances
Awards
- America's Top Doctors
- America's Top Doctors for Cancer
- CMS Meaningful Use Stage 1 Certification
- Redbook Magazine: Top Breast Cancer Doctors
- Fellow (FACP)
- Whos Who in Medicine and Healthcare
- Super Doctor
- Top MD
Education
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Christian Medical College Ludhiana
Hospital
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Froedtert Memorial Lutheran Hospital
Drug Facts
| NPI NUMBER | 1215987748 | |
| NPPES Provider LastName | CHITAMBAR | |
| NPPES Provider FirstName | CHRISTOPHER | |
| NPPES Provider ZIPCode | 532263522 | |
| NPPES Provider State | WI | |
| Specialty Description | Hematology/Oncology | |
| Total Claim Count | 269.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1215987748 |
| Last Name Of The Provider | CHITAMBAR |
| First Name Of The Provider | CHRISTOPHER |
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