Physician
Emergency Medicine
Dr. Charles H. Nightingale, MD
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Doctor Charles H. Nightingale, MD practices Emergency Medicine. Charles Nightingale has written publications. He has 100 publications published with PubMed. The lastest paper is: 'Trovafloxacin: fourth generation fluoroquinolone.' Charles H. Nightingale accepts Medicare payments and is registered with Medicare.gov.
Publications
- Pharmacodynamic profiling of modithromycin: Assessment in a pneumococcal murine pneumonia model.
- Comparative in vivo efficacy of meropenem, imipenem, and cefepime against Pseudomonas aeruginosa expressing MexA-MexB-OprM efflux pumps.
- Impact of extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species on clinical outcomes and hospital costs: a matched cohort study.
- Population pharmacokinetic analysis and dosing regimen optimization of meropenem in adult patients.
- Tissue penetration of telavancin after intravenous administration in healthy subjects.
- Population pharmacokinetics and pharmacodynamics of meropenem in pediatric patients.
- Future in vitro and animal studies: development of pharmacokinetic and pharmacodynamic efficacy predictors for tissue-based antibiotics.
- Comparison of pharmacodynamic target attainment between healthy subjects and patients for ceftazidime and meropenem.
- Pharmacokinetic profile of tigecycline in serum and skin blister fluid of healthy subjects after multiple intravenous administrations.
- Pharmacodynamic profile of ertapenem against Klebsiella pneumoniae and Escherichia coli in a murine thigh model.
- Pharmacodynamic profile of telithromycin against macrolide- and fluoroquinolone-resistant Streptococcus pneumoniae in a neutropenic mouse thigh model.
- Quantitation of tigecycline, a novel glycylcycline [corrected] by liquid chromatography.
- Optimizing pharmacodynamic target attainment using the MYSTIC antibiogram: data collected in North America in 2002.
- Clinical and economic benefits of a meropenem dosage strategy based on pharmacodynamic concepts.
- Determination of the in vivo pharmacodynamic profile of cefepime against extended-spectrum-beta-lactamase-producing Escherichia coli at various inocula.
- Review of the pharmacodynamics of antibiotic use in animal food production.
- Prevalence of extended spectrum beta-lactamase producing Escherichia coli and Klebsiella isolates in a large community teaching hospital in Connecticut.
- Pharmacodynamics of moxifloxacin and levofloxacin at simulated epithelial lining fluid drug concentrations against Streptococcus pneumoniae.
- Pharmacokinetic properties and stability of continuous-infusion meropenem in adults with cystic fibrosis.
- Pharmacodynamics of meropenem and imipenem against Enterobacteriaceae, Acinetobacter baumannii, and Pseudomonas aeruginosa.
- Emerging Pseudomonas aeruginosa resistance: implications in clinical practice.
- Cost analysis of continuous versus intermittent infusion of piperacillin-tazobactam: a time-motion study.
- Use of Monte Carlo simulation to design an optimized pharmacodynamic dosing strategy for meropenem.
- Simultaneous determination of ticarcillin and clavulanate in rabbit serum and tissue cage fluid by liquid chromatography.
- Impact of pharmacodynamics on dosing of macrolides, azalides, and ketolides.
- Pharmacokinetics of meropenem 0.5 and 2 g every 8 hours as a 3-hour infusion.
- Pharmacokinetic profile of meropenem, administered at 500 milligrams every 8 hours, in plasma and cantharidin-induced skin blister fluid.
- Pharmacodynamics of a novel des-F(6)-quinolone, BMS-284756, against Streptococcus pneumoniae in the thigh infection model.
- Role of pharmacodynamics in designing dosage regimens for beta-lactams.
- Economic benefit of a meropenem dosage strategy based on pharmacodynamic concepts.
- Utilization of extended-spectrum beta-lactamase (ESBL) detection systems in microbiology laboratories: survey of Connecticut hospitals from 1998-2002.
- Treatment of Clostridium difficile-associated disease (CDAD).
- Cost effect of managing methicillin-resistant Staphylococcus aureus in a long-term care facility.
- Pharmacoeconomics of a pharmacist-managed program for automatically converting levofloxacin route from i.v. to oral.
- Bactericidal effect and pharmacodynamics of cethromycin (ABT-773) in a murine pneumococcal pneumonia model.
- Pharmacodynamic profiling of continuously infused piperacillin/tazobactam against Pseudomonas aeruginosa using Monte Carlo analysis.
- Pharmacodynamic assessment of clarithromycin in a murine model of pneumococcal pneumonia.
- Pharmacokinetic and pharmacodynamic evaluation of two dosing regimens for piperacillin-tazobactam.
- Extended-spectrum beta-lactamases (ESBL).
- Influence of variable milk quality premiums on observed milk quality.
- Antibiotic use in animals.
- A clinical investigation of force delivery systems for orthodontic space closure.
- Effectiveness of a writing improvement intervention program on the readability of the research informed consent document.
- Belle Maudsley Lecture 2001. Risk management in orthodontics--making clinical practice safer.
- The use of vacuum-formed splints for temporary intermaxillary fixation in the management of unilateral condylar fractures.
- Professional flexibility.
- Guidelines for treatment of community-acquired pneumonia.
- Phonological awareness therapy and articulatory training approaches for children with phonological disorders: a comparative outcome study.
- In vitro antimicrobial susceptibility of glycopeptide-resistant enterococci.
- Lack of interaction between levofloxacin and oxycodone: pharmacokinetics and drug disposition.
- Trovafloxacin: fourth generation fluoroquinolone.
- Lignocaine test doses to detect intravenous injection.
- A new treatment for epidural opioid induced pruritus in parturients.
- Informed consent for research: a study to evaluate readability and processability to effect change.
- Antiseptic-bonded central venous catheters and bacterial colonisation.
- Inserting central venous catheters. Difficulties are rare and do not correlate with lifespan of catheter.
- Efficacies of liposome-encapsulated clarithromycin and ofloxacin against Mycobacterium avium-M. intracellulare complex in human macrophages.
- Bactericidal activity of low-dose ceftizoxime plus metronidazole compared with cefoxitin and ampicillin-sulbactam.
- Intelligent dosing of antimicrobials.
- Optimal times above MICs of ceftibuten and cefaclor in experimental intra-abdominal infections.
- Loss of bactericidal activities of quinolones during the post-antibiotic effect induced by rifampicin.
- Caution in the use of commercial serum.
- Stability of aztreonam and ampicillin sodium-sulbactam sodium in 0.9% sodium chloride injection.
- Reduction in serum concentrations of ciprofloxacin after administration of ursodiol to a patient with hepatobiliary disease.
- Minocycline versus vancomycin for treatment of experimental endocarditis caused by oxacillin-resistant Staphylococcus aureus.
- An improved HPLC assay for ciprofloxacin in biological samples.
- Serum bactericidal activity of ceftriaxone plus metronidazole against common intra-abdominal pathogens.
- Effect of continuous arteriovenous hemodiafiltration on the pharmacokinetics of fluconazole.
- Treatment of uncomplicated infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae.
- Enhanced killing of methicillin-resistant Staphylococcus aureus in human macrophages by liposome-entrapped vancomycin and teicoplanin.
- Intracellular and extracellular penetration of azithromycin into inflammatory and noninflammatory blister fluid.
- Experience with a once-daily aminoglycoside program administered to 2,184 adult patients.
- Continuous infusion of beta-lactam antibiotics: a rational dosing approach.
- Stability of cefotaxime sodium and metronidazole in 0.9% sodium chloride injection or in ready-to-use metronidazole bags.
- Influence of aspirin on development and treatment of experimental Staphylococcus aureus endocarditis.
- Comparison of the pharmacodynamic activity of cefotaxime plus metronidazole with cefoxitin and ampicillin plus sulbactam.
- Comparative efficacies of levofloxacin and ciprofloxacin against Streptococcus pneumoniae in a mouse model of experimental septicaemia.
- Pharmacodynamics of intermittent- and continuous-infusion cefepime alone and in combination with once-daily tobramycin against Pseudomonas aeruginosa in an in vitro in...
- Pharmacokinetics of ticlopidine in the rabbit.
- Pharmacokinetics of 5-fluorouracil and its penetration into pancreatic juice in dogs.
- Continuous infusion of beta-lactam antibiotics.
- Pharmacokinetics of rifapentine in subjects seropositive for the human immunodeficiency virus: a phase I study.
- Beneficial effect of combination antiplatelet therapy on the development of experimental Staphylococcus aureus endocarditis.
- Pharmacoeconomics of Pneumocystis carinii pneumonia in HIV-infected and HIV-noninfected patients.
- Choosing a bronchodilator for asthma therapy: the role of rapid onset of action.
- Implementation of a once-daily aminoglycoside program in a large community-teaching hospital.
- How to develop critical paths and prepare for other formulary management changes.
- Bioavailability of fluconazole administered via a feeding tube in intensive care unit patients.
- In vitro elution of ofloxacin from a bioabsorbable polymer.
- Activities of clarithromycin, azithromycin, and ofloxacin in combination with liposomal or unencapsulated granulocyte-macrophage colony-stimulating factor against intr...
- The use of zidovudine to prevent perinatal transmission of HIV.
- Clinical pharmacokinetics of newer cephalosporins.
- Pharmacokinetics of cefotaxime in healthy volunteers and patients.
- Cephalosporin-metronidazole combinations in the management of intra-abdominal infections.
- Infectious Diseases Society of America position statement on infectious diseases physicians and hospital pharmacists: comment and editorial.
- The pharmacodynamics of aminoglycosides.
- Myoglobin clearance during continuous veno-venous hemofiltration with or without dialysis.
- Formulary review of the carbapenems: comparison of imipenem/cilastatin and meropenem.
- Influence of adjunctive ticlopidine on the treatment of experimental Staphylococcus aureus endocarditis.
Schools
Mi State Univ Coll Human Med
Doctors Specialties
- Emergency Medicine
Accepted Insurances
Drug Facts
| NPI NUMBER | 1053360040 | |
| NPPES Provider LastName | NIGHTINGALE | |
| NPPES Provider FirstName | CHARLES | |
| NPPES Provider ZIPCode | 486012551 | |
| NPPES Provider State | MI | |
| Specialty Description | Emergency Medicine | |
| Total Claim Count | 309.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 55.0 | |
| Percent Opioid Claims | 17.8 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1053360040 |
| Last Name Of The Provider | NIGHTINGALE |
| First Name Of The Provider | CHARLES |
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