Physician
General Surgery
Dr. Charles F. Shield, MD
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Doctor Charles F. Shield, MD works in the field of General Surgery. He researched medicine at Washington University School of Medicine in St. Louis. He received awards:"Fellow (FACS)". Charles Shield is a published physician. He has 100 papers published. The most current publication "Long-term graft survival is improved in cadaveric renal retransplantation by flow cytometric crossmatching."
Publications
- Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly.
- Stem cell therapies benefit Alport syndrome.
- Long-term survival of kidneys transplanted from live A2 donors to O and B recipients.
- Renal graft survival is not influenced by a positive flow B-cell crossmatch.
- Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.
- Successful renal transplantation despite low levels of donor-specific HLA class I antibody without IVIg or plasmapheresis.
- Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney Disease.
- Improving access to kidney transplantation without decreasing graft survival: long-term outcomes of blood group A2/A2B deceased donor kidneys in B recipients.
- ABO blood group influences a candidate''s likelihood of receiving an HLA zero antigen mismatch kidney.
- The risk for Chagas'' Disease in the Midwestern United States organ donor population is low.
- Transplantation of A2 and A2B kidneys from deceased donors into B waiting list candidates increases their transplantation rate.
- Randomized trial of tacrolimus + mycophenolate mofetil or azathioprine versus cyclosporine + mycophenolate mofetil after cadaveric kidney transplantation: results at t...
- Point-of-care testing in an organ procurement organization donor management setting.
- HLA points assigned in cadaveric kidney allocation should be revisited: an analysis of HLA class II molecularly typed patients and donors.
- Flow cytometry beads rather than the antihuman globulin method should be used to detect HLA Class I IgG antibody (PRA) in cadaveric renal regraft candidates.
- IgM antibodies identified by a DTT-ameliorated positive crossmatch do not influence renal graft outcome but the strength of the IgM lymphocytotoxicity is associated wi...
- The influence of age, gender and ethnicity on cadaveric organ recovery rate.
- Increased access to transplantation for blood group B cadaveric waiting list candidates by using A2 kidneys: time for a new national system?
- Effect of donor brain-death duration on graft outcome.
- Randomized trial of tacrolimus plus mycophenolate mofetil or azathioprine versus cyclosporine oral solution (modified) plus mycophenolate mofetil after cadaveric kidne...
- Cold ischemia time: an independent predictor of increased HLA class I antibody production after rejection of a primary cadaveric renal allograft.
- Randomized trial of tacrolimus (Prograf) in combination with azathioprine or mycophenolate mofetil versus cyclosporine (Neoral) with mycophenolate mofetil after cadave...
- Identification of alpha3, alpha4, and alpha5 chains of type IV collagen as alloantigens for Alport posttransplant anti-glomerular basement membrane antibodies.
- Successful cadaveric renal transplantation of patients highly sensitized to HLA Class I antigens.
- Role for transforming growth factor-beta1 in alport renal Disease progression.
- Determinants of waiting time for heart transplants in the United States.
- Influence of an historically positive crossmatch on cadaveric renal transplantation.
- Long-term graft survival is improved in cadaveric renal retransplantation by flow cytometric crossmatching.
- Transplantation rate of the blood group B waiting list is increased by using A2 and A2B kidneys.
- Center-specific graft and patient survival rates: 1997 United Network for Organ Sharing (UNOS) report.
- Influence of the Rh (D) blood group system on graft survival in renal transplantation.
- ABO-mismatched renal transplantation in children: a report of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS) and the Midwest Organ Bank (MOB).
- Ten-year experience in transplantation of A2 kidneys into B and O recipients.
- Assessment of health-related quality of life in kidney transplant patients receiving tacrolimus (FK506)-based versus cyclosporine-based immunosuppression. FK506 Kidney...
- Use of gadolinium-enhanced, ultrafast, three-dimensional, spoiled gradient-echo magnetic resonance angiography in the preoperative evaluation of living renal allograft...
- Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility.
- Antilymphocyte induction therapy in cadaver renal transplantation: a retrospective, multicenter United Network for Organ Sharing Study.
- Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endopr...
- HLA-DR and DQ typing by polymerase chain reaction using sequence-specific primer mixes reduces the incidence of phenotypic homozygosity (blanks) over serology.
- A cost-effectiveness analysis of OKT3 induction therapy in cadaveric kidney transplantation.
- Improved graft survival in cadaveric renal retransplantation by flow crossmatching.
- OKT3 prophylaxis in renal grafts with prolonged cold ischemia times: association with improvement in long-term survival.
- Allocation of kidneys to Afro-American patients is proportional to wait-list composition.
- Do African-Americans wait longer for a kidney because of HLA class I antibody specificities and panel-reactive antibody sensitization?
- Evaluation of the 3.0 Ortho EIA assay in 385 consecutive cadaveric organ donors.
- Detection of HLA IgG antibodies by two enzyme-linked immunoassays, solubilized HLA class I and PRA-STAT. Comparison with the AHG PRA.
- Docking of puppies'' tails.
- The OKT3 Antibody Response Study: a multicentre study of human anti-mouse antibody (HAMA) production following OKT3 use in solid organ transplantation.
- OKT3 prophylaxis improves long-term renal graft survival in high-risk patients as compared to cyclosporine: combined results from the prospective, randomized Belgian a...
- Incidence of a positive final antiglobulin (AHG) T-cell crossmatch in patients waiting for cadaveric renal transplantation is not influenced by race of recipient.
- Impact of HLA DR typing by polymerase chain reaction amplification with DR beta 1 sequence-specific primers on cadaveric renal allocation.
- Safety of OKT3 use in the operating room.
- Consensus statement regarding OKT3-induced cytokine-release syndrome and human antimouse antibodies.
- Consequences of anti-OKT3 antibody development: OKT3 reuse and long-term graft survival.
- OKT3 antibody response study: comparative testing of human antimouse antibody.
- The effects of intraoperative administration of OKT3 during renal transplantation.
- Relationship between clinical outcome, inpatient length of stay, and cost of renal transplantation at four US transplant centers.
- OKT3 antibody response study (OARS): a multicenter comparative study.
- Incidence and clinical impact of hepatitis C virus-positive donors in cadaveric transplantation.
- A randomized clinical trial of induction therapy with OKT3 in kidney transplantation.
- Current experience with renal transplantation across the ABO blood group barrier.
- Influence of race, PRA level, and gender on the incidence of a positive donor-specific preliminary T cell crossmatch.
- Influence of HLA and race on long-term cadaveric renal transplantation.
- Inguinal herniorrhaphy in the continuous ambulatory peritoneal dialysis patient.
- Current experience with renal transplantation across the ABO barrier.
- Injuries from air-guns.
- Use of indomethacin to minimize the adverse reactions associated with orthoclone OKT3 treatment of kidney allograft rejection.
- Hygroma renalis: two cases within a family and a literature review.
- Factors affecting the waiting time of cadaveric kidney transplant candidates in the United States.
- Thyroid adenomata and renal tumours.
- Removal of an intra-Abdominal egg from a chicken.
- Effective induction immunosuppression for cadaver renal transplantation at the St. Francis Regional Medical Center.
- The reuse of OKT3 after previous rejection or induction therapy in cadaveric renal transplantation.
- The human antimouse reaction to OKT3: cross-reactive pattern analysis using a large group of anti-CD3 and isotypic monoclonal antibodies.
- Effectiveness of a second course of OKT3 monoclonal anti-T cell antibody for treatment of renal allograft rejection.
- Recurrence of acute rejection in the absence of CD3-positive lymphocytes.
- Immunologic monitoring during and after OKT3 therapy.
- Early use of OKT3 monoclonal antibody in renal transplantation to prevent rejection.
- Successful transplantation of blood group A2 kidneys into non-A recipients.
- Unusual drug reaction.
- The Kell system and kidney transplantation.
- A U.S. clinical study of Orthoclone OKT3 in renal transplantation.
- Human antibody response to antilymphocytic preparations in renal transplant patients.
- Comparison of antimouse and antihorse antibody production during the treatment of allograft rejection with OKT3 or antithymocyte globulin.
- Therapeutic use of OKT3 monoclonal antibody for acute renal allograft rejection.
- OKT3 monoclonal antibody plasma levels during therapy and the subsequent development of host antibodies to OKT3.
- The association of antiVascular endothelial cell antibody with hyperacute rejection: a case report.
- OKT3 monoclonal antibody reversal of acute renal allograft rejection unresponsive to conventional immunosuppressive treatments.
- Perforated duodenal diverticulum: treatment by tube duodenostomy.
- Renal transplant perfusion during aortoiliac Aneurysmectomy.
- Acute diverticulitis. Comparison of treatment in immunocompromised and nonimmunocompromised patients.
- Posttransplant immune monitoring with monoclonal antibodies.
- Stability of human lymphocyte differentiation antigens when stored at room temperature.
- Grand rounds from Wilford Hall USAF Medical Center: evaluation of surgical risk.
- Humoral immunity in renal transplantation Detection of cytotoxic antibodies to lymphocyte antigens Other than HLA-A,B,C and Ia-like antigens in patients with vascular ...
- Kidney transplantation at Wilford Hall USAF Medical Center.
- Safe, cost-effective postoperative nutrition. Defined formula diet via needle-catheter jejunostomy.
- Use of antithymocyte globulin for reversal of acute allograft rejection.
- Prolongation of allograft survival by cyclosporin A.
Schools
Washington University St Louis
Wilford Hall Usaf Med Center
Massachusetts General Hospital
Procedures Preformed
- Adrenalectomy
- Appendectomy, Laparoscopic
- Appendectomy, Open
- Arteriovenous Shunt Creation
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Conditions Treated
- Abdominal Pain
- Appendicitis
- Cholecystitis and Gallstones
- Colorectal Cancer
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Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- Fellow (FACS)
Education
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Massachusetts General Hospital -
San Antonio Uniformed Services Health Education Consortium -
Washington University School of Medicine in St. Louis
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