Physician
Cardiology
Dr. Charles E. O'Brien Jr., DO
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Charles E. O'Brien Jr., DO practices Cardiology. He went to medical school at Creighton University School of Medicine. Creighton University School of Medicine has a rank of 79 in research and a 78 in primary care He received awards:"Elected Member". Charles O'Brien is a published doctor. He published 94 publications, including: 'Naltrexone vs Placebo for the Treatment of Alcohol Dependence: A Randomized Clinical Trial.' Charles O'Brien is registered with Medicare.
Publications
- Naltrexone vs Placebo for the Treatment of Alcohol Dependence: A Randomized Clinical Trial.
- Extended-release naltrexone to prevent relapse among opioid dependent, criminal justice system involved adults: Rationale and design of a randomized controlled effecti...
- Brief report: "Spiders-No, Puppies-Go", introducing a novel Go NoGo task tested in inner city adolescents at risk for poor impulse control.
- A pilot trial of injectable, extended-release naltrexone for the treatment of co-occurring cocaine and alcohol dependence.
- Or14-4effectiveness of extended-release naltrexone (xr-ntx) among criminal justice-involved persons with opioid use disorders.
- Nipping cue reactivity in the bud: baclofen prevents limbic activation elicited by subliminal drug cues.
- Extended-release naltrexone modulates brain response to drug cues in abstinent heroin-dependent patients.
- Neural correlates of attentional bias for smoking cues: modulation by variance in the dopamine transporter gene.
- The Dopamine Receptor D2 (DRD2) SNP rs1076560 is Associated with Opioid Addiction.
- Neural responses to subliminally presented cannabis and other emotionally evocative cues in cannabis-dependent individuals.
- Classification and definition of misuse, abuse, and related events in clinical trials: ACTTION systematic review and recommendations.
- Abuse liability measures for use in analgesic clinical trials in patients with pain: IMMPACT recommendations.
- A Cross-Sectional Study of Attitudes About the Use of Genetic Testing for Clinical Care Among Patients with an Alcohol Use Disorder.
- Concurrent naltrexone and prolonged exposure therapy for patients with comorbid alcohol dependence and PTSD: a randomized clinical trial.
- Results from a pilot clinical trial of varenicline for the treatment of alcohol dependence.
- A double-blind, placebo-controlled trial of topiramate for the treatment of comorbid cocaine and alcohol dependence.
- Case-control association study of WLS variants in opioid and cocaine addicted populations.
- Low frequency genetic variants in the ?-opioid receptor (OPRM1) affect risk for addiction to heroin and cocaine.
- Wavelet-transformed temporal cerebral blood flow signals during attempted inhibition of cue-induced cocaine craving distinguish prognostic phenotypes.
- Current status of co-occurring mood and substance use disorders: a new therapeutic target.
- Depot naltrexone decreases rewarding properties of sugar in patients with opioid dependence.
- Results of an initial clinical trial of varenicline for the treatment of cocaine dependence.
- The Alcohol Clinical Trials Initiative (ACTIVE): Purpose and Goals for Assessing Important and Salient Issues for Medications Development in Alcohol Use Disorders.
- Further evidence for association of polymorphisms in the CNR1 gene with cocaine addiction: confirmation in an independent sample and meta-analysis.
- Adapting treatment to patient problems.
- Effects of varenicline on smoking cue-triggered neural and craving responses.
- Dopamine transporter genotype modulation of neural responses to smoking cues: confirmation in a new cohort.
- Modulation of resting brain cerebral blood flow by the GABA B agonist, baclofen: A longitudinal perfusion fMRI study.
- Drug treatment as HIV prevention: a research update.
- Long-acting injectable versus oral naltrexone maintenance therapy with psychosocial intervention for heroin dependence: a quasi-experiment.
- A double-blind, placebo-controlled trial combining sertraline and naltrexone for treating co-occurring depression and alcohol dependence.
- Identifying Risk Factors for Marijuana Use Among Veterans Affairs Patients.
- Normalizing effects of modafinil on cocaine-induced sleep abnormalities.
- DAT genotype modulates brain and behavioral responses elicited by cigarette cues.
- Association between the catechol-O-methyltransferase Val158Met polymorphism and cocaine dependence.
- The CAGE questionnaire for detection of alcoholism: a remarkably useful but simple tool.
- Gender differences in predictors of treatment attrition with high dose naltrexone in cocaine and alcohol dependence.
- Preserved DNA from past clinical trials yields new information about a subtype of alcoholism.
- A 50-year-old woman addicted to heroin: review of treatment of heroin addiction.
- Gender differences with high-dose naltrexone in patients with co-occurring cocaine and alcohol dependence.
- It is time to take a stand for medical research and against terrorism targeting medical scientists.
- Menstrual cycle phase at quit date predicts smoking status in an NRT treatment trial: a retrospective analysis.
- Acute effect of methadone maintenance dose on brain FMRI response to heroin-related cues.
- Prospects for a genomic approach to the treatment of alcoholism.
- Prelude to passion: limbic activation by "unseen" drug and sexual cues.
- Clinical pharmacokinetics of lofexidine, the alpha 2-adrenergic receptor agonist, in opiate addicts plasma using a highly sensitive liquid chromatography tandem mass s...
- Toward a rational selection of treatment for addiction.
- Limbic activation to cigarette smoking cues independent of nicotine withdrawal: a perfusion fMRI study.
- Varenicline as maintenance therapy.
- A second varenicline trial.
- A new medication for the worst addiction.
- A double-blind, placebo-controlled pilot trial of quetiapine for the treatment of Type A and Type B alcoholism.
- Improving detection of adverse effects of marketed drugs.
- Issues for DSM-V: should obesity be included as a brain disorder?
- The status of naltrexone in the treatment of alcohol dependence: specific effects on heavy drinking.
- Naltrexone with or without fluoxetine for preventing relapse to heroin addiction in St. Petersburg, Russia.
- Does modafinil produce euphoria?
- The status of disulfiram: a half of a century later.
- Naltrexone inhibits alcohol-mediated enhancement of HIV infection of T lymphocytes.
- What's in a word? Addiction versus dependence in DSM-V.
- Injectable, sustained-release naltrexone for the treatment of opioid dependence: a randomized, placebo-controlled trial.
- Medical education and treatment of addictive disorders.
- Confirmation of the association between a polymorphism in the promoter region of the prodynorphin gene and cocaine dependence.
- Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence.
- Addiction and the medical profession.
- Adolescent opioid abuse.
- Alcohol suppresses IL-2-induced CC chemokine production by natural killer cells.
- Anticraving medications for relapse prevention: a possible new class of psychoactive medications.
- Clinical implications of cocaine-induced cortical depression.
- Novel exonic mu-opioid receptor gene (OPRM1) polymorphisms not associated with opioid dependence.
- A double-blind, placebo-controlled trial of modafinil for cocaine dependence.
- Discussion: using benzodiazepines in clinical practice.
- Benzodiazepine use, abuse, and dependence.
- Priority actions to improve the care of persons with co-occurring substance abuse and other mental disorders: a call to action.
- A case report of naltrexone for alcoholism in a liver transplant recipient: side effects and safety.
- The mosaic of addiction.
- Anticraving agents for the treatment of addictive disorders.
- Naltrexone for heroin dependence treatment in St. Petersburg, Russia.
- Cocaine dependence severity predicts outcome in outpatient detoxification from cocaine and alcohol.
- A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients.
- Alcohol potentiates hepatitis C virus replicon expression.
- Research advances in the understanding and treatment of addiction.
- Alcohol potentiates HIV-1 infection of human blood mononuclear phagocytes.
- Effect of naltrexone on oral consumption of concurrently available ethanol and cocaine in the rat.
- A comparison of the effects of 6-beta naltrexol and naltrexone on the consumption of ethanol or sucrose using a limited-access procedure in rats.
- Re: Enhancing informed consent for research and treatment.
- Decreased gray matter concentration in the insular, orbitofrontal, cingulate, and temporal cortices of cocaine patients.
- Cynthia'a dilemma.
- Concurrent cocaine withdrawal alters alcohol withdrawal symptoms.
- Aberrant behaviors in a primary care-based cohort of patients with chronic pain identified as misusing prescription opioids.
- Acquired PIK3CA amplification causes resistance to selective phosphoinositide 3-kinase inhibitors in breast cancer.
- The impact of sex on brain responses to smoking cues: a perfusion fMRI study.
- Limitations of the use of the MP-RAGE to identify neural changes in the brain: recent cigarette smoking alters gray matter indices in the striatum.
Schools
University of New England Main Campus
Doctors Specialties
- Diagnostic Radiology
- Cardiology
Accepted Insurances
Awards
- Elected Member
Education
-
Mayo School of Graduate Medical Education -
Creighton University -
Creighton University School of Medicine
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