Professor of Medicine
Gastroenterology
Dr. Charles D. Howell, MD
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Charles Howell is an expert in the field of Gastroenterology. He attended University of Alabama Medical Center. University of Alabama Medical Center has a rank of 37 in research and a 17 in primary care He over the years received 2 awards: "CMS Meaningful Use Stage 1 Certification" and "Fellow (AGAF)". Charles Howell is a published physician. He published 57 publications, including: 'The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia.'
Publications
- Comparison of functional variants in IFNL4 and IFNL3 for association with HCV clearance.
- Safety and Efficacy of Ledipasvir-Sofosbuvir in African Americans with Hepatitis C Virus Infection: A Retrospective Analysis of Phase 3 Data.
- A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of Hepatitis C virus.
- Optimum Ribavirin Exposure Overcomes Racial Disparity in Efficacy of Peginterferon and Ribavirin Treatment for Hepatitis C Genotype 1.
- End-stage renal Disease and African American race are independent predictors of mild liver fibrosis in patients with chronic hepatitis C infection.
- Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1.
- IL28B Genotype Does Not Correlate with HIV Control in African Americans.
- Quantitation of pretreatment serum interferon-γ-inducible protein-10 improves the predictive value of an IL28B gene polymorphism for Hepatitis C treatment response.
- Achieving health equity to eliminate racial, ethnic, and socioeconomic disparities in HBV- and HCV-associated liver Disease.
- Survival prediction and gene identification with penalized global AUC maximization.
- Racial disparities in liver transplantation for Hepatitis B: to be or not to be.
- Peripheral blood gene expression profile associated with sustained virologic response after peginterferon plus ribavirin therapy for chronic Hepatitis-C genotype 1.
- A functional SNP of interferon-gamma gene is important for interferon-alpha-induced and spontaneous recovery from Hepatitis C virus infection.
- Risk factors for primary hepatocellular carcinoma in black and white Americans in 2000.
- Interferon-stimulated gene expression in black and white Hepatitis C patients during peginterferon alfa-2a combination therapy.
- Racial differences in liver inflammation and fibrosis related to chronic Hepatitis C.
- Peginterferon alfa-2a (40 kd) and ribavirin for black American patients with chronic HCV genotype 1.
- Animal models of autoimmunity.
- Oligoclonal expansion of T cell receptor V beta 2 and 3 cells in the livers of mice with graft-versus-host Disease.
- A comparison of molecular and enzyme-based assays for the detection of thiopurine methyltransferase mutations.
- Toxic effects of a fungicide, 5-ethoxy-3-(trichloromethy)-1,2,4-thiadiazole (terrazole), on the hepatic drug metabolizing enzyme System in mice.
- Influence of donor base deficit status on recipient outcomes in liver transplantation.
- Continuous intravenous infusion of epoprostenol for the treatment of portopulmonary hypertension.
- Fulminant hepatic failure from the Budd-Chiari syndrome. A bridge to transplantation with transjugular intrahepatic portoSystemic shunt.
- The relationship between thiopurine methyltransferase activity and genotype in blasts from patients with acute leukemia.
- Liver Diseases.
- Successful emergency transplantation of a liver allograft from a donor maintained on extracorporeal membrane oxygenation.
- Distinctive clinical features of portopulmonary hypertension.
- Murine experimental autoimmune Hepatitis: nonspecific inflammation due to adjuvant oil.
- Simultaneous liver-kidney versus liver transplantation alone in patients with end-stage liver Disease and kidney dysfunction not on dialysis.
- The evolution of a successful liver transplant program in 1996: the clinical and administrative role of the anesthesiologist.
- Hepatic homing of mononuclear inflammatory cells isolated during murine chronic graft-vs-host Disease.
- Suppressor function of liver mononuclear cells isolated during murine chronic graft-vs-host Disease. II. Role of prostaglandins and interferon-gamma.
- Suppressor function of hepatic mononuclear inflammatory cells during murine chronic graft-vs-host Disease. I. Macrophage-enriched cells mediate suppression in the liver.
- Association of single nucleotide polymorphisms in interferon signaling pathway genes and interferon-stimulated genes with the Response to interferon therapy for chroni...
- Liver T cell subsets and adhesion molecules in murine graft-versus-host Disease.
- Biased liver T cell receptor V beta repertoire in a murine graft-versus-host Disease model.
- Contributions of donor CD4 and CD8 cells to liver injury during murine graft-versus-host Disease.
- Infectious Diseases and the liver.
- Liver transplantation improves Cirrhosis-associated impaired oral glucose tolerance.
- Changes in gene expression during pegylated interferon and ribavirin therapy of chronic Hepatitis C virus distinguish responders from nonresponders to antiviral therapy.
- Racial/ethnic disparity in kidney transplantation outcomes: influence of donor and recipient characteristics.
- Successful use of chronic epoprostenol as a bridge to liver transplantation in severe portopulmonary hypertension.
- Dobutamine stress echocardiography for preoperative cardiac risk stratification in patients undergoing orthotopic liver transplantation.
- Delayed granuloma formation in a patient with vanishing bile duct syndrome 7 years post-liver transplantation.
- Hepatitis C in African Americans: summary of a workshop.
- Peginterferon alfa-2a and ribavirin for chronic Hepatitis C genotype 1 infections in black patients: safety, tolerability and impact on sustained virologic response.
- A prospective study of the incidence and open-label treatment of interferon-induced major depressive disorder in patients with Hepatitis C.
- Role of intercellular adhesion molecule-1 and lymphocyte function-associated antigen-1 during nonsuppurative destructive cholangitis in a mouse graft-versus-host disea...
- Racial disparity in primary hepatocellular carcinoma: tumor stage at presentation, surgical treatment and survival.
- Association of interferon-alpha-induced depression and improved treatment response in patients with Hepatitis C.
- Peginterferon pharmacokinetics in African American and Caucasian American patients with Hepatitis C virus genotype 1 infection.
- Early changes in Hepatitis C virus (HCV) levels in response to peginterferon and ribavirin treatment in patients with chronic HCV genotype 1 infection.
- Changes in insulin sensitivity and body weight during and after peginterferon and ribavirin therapy for Hepatitis C.
- Natural killer inhibitory receptor expression associated with treatment failure and interleukin-28B genotype in patients with chronic Hepatitis C.
- Peginterferon and ribavirin treatment in African American and Caucasian American patients with Hepatitis C genotype 1.
Procedures Preformed
- Colonoscopy, Proctosigmoidoscopy, and Sigmoidoscopy
- Endoscopy (Esophagus, Stomach, Small Intestine)
- Liver Biopsy
Conditions Treated
- Abdominal Pain
- Anemia
- Barrett's Esophagus
- Benign Neoplasm of the Digestive System
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Doctors Specialties
- Gastroenterology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Fellow (AGAF)
Education
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University of Colorado -
Baylor College of Medicine -
University of Alabama Medical Center -
Howard University College of Medicine
Hospital
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University of Maryland Medical Center
Drug Facts
| NPI NUMBER | 1275580227 | |
| NPPES Provider LastName | HOWELL | |
| NPPES Provider FirstName | CHARLES | |
| NPPES Provider ZIPCode | 212011544 | |
| NPPES Provider State | MD | |
| Specialty Description | Gastroenterology | |
| Total Claim Count | 170.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1275580227 |
| Last Name Of The Provider | HOWELL |
| First Name Of The Provider | CHARLES |
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