Professor, Pediatrics and Microbiology, Immunology and Tropical Medicine The George Washington University Director- Program for Cell Enhancement and Technologies for Immunotherapy Children's National Health System and Chief, Division of Allergy and
Pediatric Hematology & Oncology
Dr. Catherine Bollard, MD
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Catherine Bollard practices Pediatric Hematology & Oncology. She went to medical school at University of Otago School of Medicine. She over the years received 18 awards: "Induction into the Henry Kunkel Society", "Basi Science Award", "Induction to American Society of Clinical Investigation (ASCI)", "Elected Member", "Best Abstract Award", "Publication Award in Clinical Research", "Faculty Teaching Award", "Best Oral Presentation", "Finalist, Teaching Award", "Adult BMT Teaching Award", "Best Abstract Award and Young Investigator Travel Award", "Young Investigator Award", "Pediatric BMT Teaching Award", "Young Investigator Travel Award", "Fellows Day, Best Poster Award", "HSANZ Travel Award", "Edward Roche Memorial Travel" and "Travel Award". Catherine Bollard is a published doctor. She has 99 publications published. The most current publication "Adoptive immunotherapy for primary immunodeficiency disorders with virus-specific T lymphocytes."
Publications
- Functionally Active HIV-Specific T Cells that Target Gag and Nef Can Be Expanded from Virus-Naïve Donors and Target a Range of Viral Epitopes: Implications for a Cure ...
- Adoptive immunotherapy for primary immunodeficiency Disorders with virus-specific T lymphocytes.
- Challenges in the harmonization of immune monitoring studies and trial design for Cell-based therapies in the context of hematopoietic Cell transplantation for pediatr...
- Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet enGraftment after transplantation.
- General and Virus-Specific Immune Cell Reconstitution after Double Cord Blood Transplantation.
- Pediatric Lymphomas and Histiocytic Disorders of Childhood.
- A single bout of dynamic exercise by healthy adults enhances the generation of monocyte-derived-dendritic Cells.
- Expanded Cytotoxic T-Cell Lymphocytes Target the Latent HIV Reservoir.
- Matched Related and Unrelated Donor Hematopoietic Stem Cell Transplantation for DOCK8 Deficiency.
- Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against Lymphoma and multiple myeloma target cells. P...
- Adoptive immunotherapy with the use of regulatory T Cells and virus-specific T Cells derived from cord blood.
- Broadly-specific Cytotoxic T Cells Targeting Multiple HIV Antigens Are Expanded From HIV+ Patients: Implications for Immunotherapy.
- Concise Review: Umbilical Cord Blood Transplantation: Past, Present, and Future.
- Graft Versus Leukemia Response Without Graft-versus-host Disease Elicited By Adoptively Transferred Multivirus-specific T-cells.
- Reply to s. Yuan et Al.
- Opportunities and Challenges of Proteomics in Pediatric Patients: Circulating Biomarkers After Hematopoietic Stem Cell Transplantation As a Successful Example.
- Complementation of Antigen-presenting Cells to Generate T Lymphocytes With Broad Target Specificity.
- Ultra Low-Dose IL-2 for GVHD Prophylaxis after Allogeneic Hematopoietic Stem Cell Transplantation Mediates Expansion of Regulatory T Cells without Diminishing Antivira...
- Ultra-low dose interleukin-2 promotes immune-modulating function of regulatory T Cells and natural killer Cells in healthy volunteers.
- Immunotherapy: opportunities, risks and future perspectives.
- Sustained Complete Responses in Patients With Lymphoma Receiving Autologous Cytotoxic T Lymphocytes Targeting Epstein-Barr Virus Latent Membrane Proteins.
- The time is now: moving toward virus-specific T Cells after allogeneic hematopoietic stem Cell transplantation as the standard of care.
- Low rate of infusional toxicity after expanded cord blood transplantation.
- The development of a myeloablative, reduced-toxicity, conditioning regimen for cord blood transplantation.
- Third-party umbilical cord blood-derived regulatory T cells prevent xenogenic Graft-versus-host disease.
- Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against Lymphoma and multiple myeloma target cells.
- Fucosylation with fucosyltransferase VI or fucosyltransferase VII improves cord blood enGraftment.
- Pediatric Burkitt's Lymphoma and Diffuse B-Cell Lymphoma: Are Surveillance Scans Required?
- Infusion of donor-derived CD19-redirected-virus-specific T Cells for B-Cell malignancies relapsed after allogeneic stem Cell transplant: a phase I study.
- Generation of Tumor Antigen-Specific T Cell Lines from Pediatric Patients with Acute Lymphoblastic Leukemia--Implications for Immunotherapy.
- The effects of age and latent cytomegalovirus infection on the redeployment of CD8+ T Cell subsets in response to acute exercise in humans.
- T-Cell therapies for HIV.
- Multicenter study of banked third party virus-specific T-Cells to treat severe viral infections after hematopoietic stem Cell transplantation.
- Generation of multi-leukemia antigen-specific T cells to enhance the Graft-versus-leukemia effect after allogeneic stem cell transplant.
- Cord blood Graft engineering.
- Enhancing immune reconstitution: from bench to bedside.
- Cord-blood enGraftment with ex vivo mesenchymal-cell coculture.
- Ex vivo fucosylation improves human cord blood enGraftment in NOD-SCID IL-2Rgamma(null) mice.
- Good T Cells for bad B Cells.
- Selective depletion of donor alloreactive T Cells without loss of antiviral or antileukemic responses.
- [Gene therapy of childhood cancers: current status and perspectives].
- Adoptive T-cell therapy for EBV-associated post-transplant lymphoproliferative Disease.
- A strategy for treatment of Epstein-Barr virus-positive Hodgkin''s Disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells.
- Adoptive immunotherapy for posttransplantation viral infections.
- Options for T-Cell based therapies.
- The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin Disease.
- Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes.
- Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's Disease.
- Hodgkin''s Disease: are you the type?
- Characterization of latent membrane protein 2 specificity in CTL lines from patients with EBV-positive nasopharyngeal carcinoma and Lymphoma.
- Cytomegalovirus (CMV) infections and CMV-specific Cellular immune reconstitution following reduced intensity conditioning allogeneic stem Cell transplantation with Ale...
- Adenovirus infection rates in pediatric recipients of alternate donor allogeneic bone marrow transplants receiving either antithymocyte globulin (ATG) or alemtuzumab (...
- T-Cell immunotherapy for adenoviral infections of stem-Cell transplant recipients.
- Adenoviral infections in hematopoietic stem Cell transplantation.
- Administration of latent membrane protein 2-specific cytotoxic T lymphocytes to patients with relapsed Epstein-Barr virus-positive Lymphoma.
- Adoptive T-Cell transfer in cancer immunotherapy.
- Assessing the safety of cytotoxic T lymphocytes transduced with a dominant negative transforming growth factor-beta receptor.
- In vivo expansion of LMP 1- and 2-specific T-Cells in a patient who received donor-derived EBV-specific T-Cells after allogeneic stem Cell transplantation.
- Adoptive immunotherapy for Hodgkin's Lymphoma.
- Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals.
- Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic Anemia.
- Reconstitution of adenovirus-specific Cell-mediated immunity in pediatric patients after hematopoietic stem Cell transplantation.
- T Cell therapies following hematopoietic stem Cell transplantation: surely there must be a better way than DLI?
- Autologous designer antigen-presenting Cells by gene modification of T lymphocyte blasts with IL-7 and IL-12.
- Complete responses of relapsed Lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer.
- Antigen presenting cell-mediated expansion of human umbilical cord blood yields log-scale expansion of natural killer cells with anti-Myeloma activity.
- The use of central Venous catheters (portacaths) in children with haemophilia.
- Gene-marking studies of hematopoietic Cells.
- Targeting of G(D2)-positive tumor Cells by human T lymphocytes engineered to express chimeric T-Cell receptor genes.
- Gene therapy for paediatric leukaemia.
- Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-Cell receptors: potential for improved immunotherapy.
- Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity.
- Genetically engineered T-Cells for adoptive immunotherapy.
- Immune therapy for EBV infections after hemopoietic stem-Cell transplant.
- Immunotherapy for Epstein-Barr virus-associated cancers in children.
- T Cell therapies.
- Identification of hexon-specific CD4 and CD8 T-Cell epitopes for vaccine and immunotherapy.
- Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor.
- Deficient T(H)-1 responses from TNF-alpha-matured and alpha-CD40-matured dendritic Cells.
- Immunotherapy targeting EBV-expressing lymphoproliferative Diseases.
- Current understanding of the role of Epstein-Barr virus in Lymphomagenesis and therapeutic approaches to EBV-associated Lymphomas.
- Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative Disease in transplant recipients.
- Computer-assisted quantitative evaluation of therapeutic responses for Lymphoma using serial PET/CT imaging.
- Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infectio...
- The costs and cost-effectiveness of allogeneic peripheral blood stem Cell transplantation versus bone marrow transplantation in pediatric patients with acute leukemia.
- Outcome of hematopoietic stem cell transplant as salvage therapy for Hodgkin''s Lymphoma in adolescents and young adults at a single institution.
- Antigen-specific cytotoxic T lymphocytes can target chemoresistant side-population tumor cells in Hodgkin Lymphoma.
- Adverse events following infusion of T Cells for adoptive immunotherapy: a 10-year experience.
- Management options, survivorship, and emerging treatment strategies for follicular and Hodgkin Lymphomas.
- Long-term remission in a child with refractory EBV(+) hydroa vacciniforme-like T-cell Lymphoma through sequential matched EBV(+)-related allogeneic hematopoietic SCT f...
- Cord blood natural killer Cells exhibit impaired lytic immunological synapse formation that is reversed with IL-2 exvivo expansion.
- A novel latent membrane 2 transcript expressed in Epstein-Barr virus-positive NK- and T-cell lymphoproliferative Disease encodes a target for cellular immunotherapy.
- Allogeneic virus-specific T Cells with HLA alloreactivity do not produce GVHD in human subjects.
- Improving clinical outcomes using adoptively transferred immune Cells from umbilical cord blood.
- Isolating cytomegalovirus-specific T Cells for adoptive transfer: are we there yet?
- Adoptive transfer of EBV-specific T Cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma.
- Lovastatin inhibits T-Cell proliferation while preserving the cytolytic function of EBV, CMV, and MART-1-specific CTLs.
- Novel cord blood transplant therapies.
Procedures Preformed
- HPC Transplantation (Stem Cell Transplant)
Conditions Treated
- Anemia
- Coagulation Disorders (incl. Hemophilia)
- Deep Vein Thrombosis (DVT)
- Graft vs Host Disease
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Doctors Specialties
- Hematology
- Pediatric Hematology
- Oncology
Accepted Insurances
Awards
- Induction into the Henry Kunkel Society
- Basi Science Award
- Induction to American Society of Clinical Investigation (ASCI)
- Elected Member
- Best Abstract Award
- Publication Award in Clinical Research
- Faculty Teaching Award
- Best Oral Presentation
- Finalist, Teaching Award
- Adult BMT Teaching Award
- Best Abstract Award and Young Investigator Travel Award
- Young Investigator Award
- Pediatric BMT Teaching Award
- Young Investigator Travel Award
- Fellows Day, Best Poster Award
- HSANZ Travel Award
- Edward Roche Memorial Travel
- Travel Award
Education
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University of Otago School of Medicine
Hospital
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Texas Children's Hospital
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