Physician
Internal Medicine
Dr. Caroline C. Philpott, MD
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Caroline Philpott practices Internal Medicine. She attended Duke University School of Medicine. Duke University School of Medicine is one of the top medical schools in the US. Duke University School of Medicine has a rank of 8 in research and a 29 in primary care She received awards:"Elected Member". Caroline Philpott is also published. She has 40 publications published. The lastest publication: "Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast.'
Publications
- Iron chaperones PCBP1 and PCBP2 mediate the metallation of the dinuclear iron enzyme deoxyhypusine hydroxylase.
- Heme Uptake by Leishmania amazonensis Is Mediated by the Transmembrane Protein LHR1.
- Topologically conserved residues direct heme transport in HRG-1-related proteins.
- Activation of the HIF Prolyl Hydroxylase by the Iron Chaperones PCBP1 and PCBP2.
- Phosphatidylserine is involved in the ferrichrome-induced plasma membrane trafficking of Arn1 in Saccharomyces cerevisiae.
- Metabolic response to iron deficiency in Saccharomyces cerevisiae.
- Gga2 mediates sequential ubiquitin-independent and ubiquitin-dependent steps in the trafficking of ARN1 from the trans-Golgi network to the vacuole.
- A cytosolic iron chaperone that delivers iron to ferritin.
- Role of PUG1 in inducible porphyrin and heme transport in Saccharomyces cerevisiae.
- Response to iron deprivation in Saccharomyces cerevisiae.
- GGA2- and ubiquitin-dependent trafficking of Arn1, the ferrichrome transporter of Saccharomyces cerevisiae.
- A screen for genes of heme uptake identifies the FLC family required for import of FAD into the endoplasmic reticulum.
- Transcriptional remodeling in response to iron deprivation in Saccharomyces cerevisiae.
- Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae.
- The mechanism of ferrichrome transport through Arn1p and its metabolism in Saccharomyces cerevisiae.
- Molecular aspects of iron absorption: Insights into the role of HFE in hemochromatosis.
- Developmental expression of ZP3, a mouse zona pellucida gene.
- A regulated RNA binding protein also possesses aconitase activity.
- Sequence and expression of the murine iron-responsive element binding protein.
- Modification of a free Fe-S cluster cysteine residue in the active iron-responsive element-binding protein prevents RNA binding.
- Expression of a constitutive mutant of iron regulatory protein 1 abolishes iron homeostasis in mammalian cells.
- Differences in the RNA binding sites of iron regulatory proteins and potential target diversity.
- An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein.
- The response to iron deprivation in Saccharomyces cerevisiae: expression of siderophore-based systems of iron uptake.
- The bifunctional iron-responsive element binding protein/cytosolic aconitase: the role of active-site residues in ligand binding and regulation.
- Identification of a Candida albicans ferrichrome transporter and its characterization by expression in Saccharomyces cerevisiae.
- Cell-cycle arrest and inhibition of G1 cyclin translation by iron in AFT1-1(up) yeast.
- The role of the FRE family of plasma membrane reductases in the uptake of siderophore-iron in Saccharomyces cerevisiae.
- Siderophore-iron uptake in saccharomyces cerevisiae. Identification of ferrichrome and fusarinine transporters.
- Desferrioxamine-mediated iron uptake in Saccharomyces cerevisiae. Evidence for two pathways of iron uptake.
- Three cell wall mannoproteins facilitate the uptake of iron in Saccharomyces cerevisiae.
- Ferrichrome induces endosome to plasma membrane cycling of the ferrichrome transporter, Arn1p, in Saccharomyces cerevisiae.
- Fep1 represses expression of the fission yeast Schizosaccharomyces pombe siderophore-iron transport system.
- Iron-dependent metabolic remodeling in S. cerevisiae.
- A receptor domain controls the intracellular sorting of the ferrichrome transporter, ARN1.
- Iron uptake in fungi: a system for every source.
- Development of a transformation system for gene knock-out in the flavinogenic yeast Pichia guilliermondii.
- Deficiency in frataxin homologue YFH1 in the yeast Pichia guilliermondii leads to missregulation of iron acquisition and riboflavin biosynthesis and affects sulfate as...
- Identification of the genes affecting the regulation of riboflavin synthesis in the flavinogenic yeast Pichia guilliermondii using insertion mutagenesis.
Schools
Duke University
Doctors Specialties
- Internal Medicine
Accepted Insurances
Awards
- Elected Member
Education
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Johns Hopkins University -
Duke University School of Medicine
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