Physician
Pathology
Dr. Candece L. Gladson, MD
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Candece Gladson works in the field of Pathology. She graduated from Loyola University Chicago Stritch School of Medicine. Candece Gladson is also published. She has 77 publications published. The lastest publication: "The role of integrins in the malignant phenotype of gliomas.'
Publications
- Cancer stem cell-specific scavenger receptor CD36 drives glioblastoma progression.
- FAK-Related Nonkinase Is a Multifunctional Negative Regulator of Pulmonary Fibrosis.
- Laminin alpha 2 enables glioblastoma stem cell growth.
- Downregulation of FIP200 Induces Apoptosis of Glioblastoma Cells and Microvascular Endothelial Cells by Enhancing Pyk2 Activity.
- Downregulation of FAK-related non-kinase mediates the migratory phenotype of human fibrotic lung fibroblasts.
- Histidine-rich glycoprotein modulates the anti-angiogenic effects of vasculostatin.
- A phase 1 trial of ABT-510 concurrent with standard chemoradiation for patients with newly diagnosed glioblastoma.
- The pathobiology of glioma tumors.
- Urokinase receptor mediates lung fibroblast attachment and migration toward provisional matrix proteins through interaction with multiple integrins.
- Plasminogen kringle 5 induces apoptosis of brain microvessel endothelial cells: sensitization by radiation and requirement for GRP78 and LRP1.
- Thrombospondin-1-induced apoptosis of brain microvascular endothelial cells can be mediated by TNF-R1.
- New insights into the role of CXCR4 in prostate cancer metastasis.
- Focal adhesion kinase (FAK)-related non-kinase inhibits myofibroblast differentiation through differential MAPK activation in a FAK-dependent manner.
- ABT-510, a modified type 1 repeat peptide of thrombospondin, inhibits malignant glioma growth in vivo by inhibiting angiogenesis.
- New concepts regarding focal adhesion kinase promotion of cell migration and proliferation.
- Syndecan-2 is expressed in the microvasculature of gliomas and regulates angiogenic processes in microvascular endothelial cells.
- Low-density lipoprotein receptor-related protein contributes to the antiangiogenic activity of thrombospondin-2 in a murine glioma model.
- Inhibition of cystine uptake disrupts the growth of primary brain tumors.
- Lyn kinase activity is the predominant cellular SRC kinase activity in glioblastoma tumor cells.
- Endogenous inhibitors of angiogenesis in malignant gliomas: nature's antiangiogenic therapy.
- p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mo...
- Could labeled neuronal progenitor cells be used to target glioma tumor endothelium?
- Preterm fetal hypoxia-ischemia causes hypertonia and motor deficits in the neonatal rabbit: a model for human cerebral palsy?
- The pattern of enhancement of Src kinase activity on platelet-derived growth factor stimulation of glioblastoma cells is affected by the integrin engaged.
- Expression of extracellular matrix metalloprotease inducer in laryngeal squamous cell carcinoma.
- Focal adhesion kinase is expressed in the angiogenic blood vessels of malignant astrocytic tumors in vivo and promotes capillary tube formation of brain microvascular ...
- Focal adhesion kinase in cancer.
- FAK signaling in anaplastic astrocytoma and glioblastoma tumors.
- Promotion of malignant astrocytoma cell migration by osteopontin expressed in the normal brain: differences in integrin signaling during cell adhesion to osteopontin v...
- Focal adhesion kinase enhances signaling through the Shc/extracellular signal-regulated kinase pathway in anaplastic astrocytoma tumor biopsy samples.
- Adenovirally mediated expression of urokinase receptor binding site on integrin alpha-chain blocks adhesion and migration of human lung fibroblasts.
- Lyn Facilitates Glioblastoma Cell Survival under Conditions of Nutrient Deprivation by Promoting Autophagy.
- New molecular targets in angiogenic vessels of glioblastoma tumours.
- Targeting SRC in glioblastoma tumors and brain metastases: rationale and preclinical studies.
- Progress on antiangiogenic therapy for patients with malignant glioma.
- A novel technique to quantify glioma tumor invasion using serial microscopy sections.
- The role of the extracellular matrix in angiogenesis in malignant glioma tumors.
- Oncostatin-M induction of vascular endothelial growth factor expression in astroglioma cells.
- Overexpression of FAK promotes Ras activity through the formation of a FAK/p120RasGAP complex in malignant astrocytoma cells.
- Elevated expression of TGF-beta1 in head and neck cancer-associated fibroblasts.
- New approaches to the molecular biology, classification, and therapy of nervous system tumors: a workshop of the National Institutes of Health Pathology B study section.
- Paradoxical labeling of radiosurgically treated quiescent tumors with Ki67, a marker of cellular proliferation.
- The extracellular matrix of gliomas: modulation of cell function.
- Increased injury following intermittent fetal hypoxia-reoxygenation is associated with increased free radical production in fetal rabbit brain.
- Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth.
- Vitronectin, a glioma-derived extracellular matrix protein, protects tumor cells from apoptotic death.
- Retinoic acid alters the mechanism of attachment of malignant astrocytoma and neuroblastoma cells to thrombospondin-1.
- Glioma migration can be blocked by nontoxic inhibitors of myosin II.
- The role of integrins in the malignant phenotype of gliomas.
- Biological significance of the expression of urokinase-type plasminogen activator receptors (uPARs) in brain tumors.
- Sustained hypoxia-ischemia results in reactive nitrogen and oxygen species production and injury in the premature fetal rabbit brain.
- Vitronectin expression in differentiating neuroblastic tumors: integrin alpha v beta 5 mediates vitronectin-dependent adhesion of retinoic-acid-differentiated neurobla...
- Ligation of integrin alpha5beta1 is required for internalization of vitronectin by integrin alphavbeta3.
- Expression of integrin alpha v beta 3 in small blood vessels of glioblastoma tumors.
- Stage-specific expression of integrin alphaVbeta3 in neuroblastic tumors.
- Stearate inhibits human tumor cell invasion.
- Up-regulation of urokinase and urokinase receptor genes in malignant astrocytoma.
- Changes in procoagulant and fibrinolytic gene expression during bleomycin-induced lung injury in the mouse.
- Cerebral microenvironment influences expression of the vitronectin gene in astrocytic tumors.
- Hypocellular bone marrow with increased blasts.
- Mechanism of protein C-dependent clot lysis: role of plasminogen activator inhibitor.
- The frequency of type I heterozygous protein S and protein C deficiency in 141 unrelated young patients with venous thrombosis.
- Coumarin necrosis, neonatal purpura fulminans, and protein C deficiency.
- A comparison between activated protein C and des-1-41-light chain-activated protein C in reactions with type 1 plasminogen activator inhibitor.
- Perimyositis with perineuritis and myofiber type grouping in the eosinophilia myalgia syndrome associated with tryptophan ingestion.
- Neonatal subependymal giant cell astrocytoma associated with tuberous sclerosis: MRI, CT, and ultrasound correlation.
- Correlation of chondroitin sulfate proteoglycan expression on proliferating brain capillary endothelial cells with the malignant phenotype of astroglial cells.
- Glioblastoma expression of vitronectin and the alpha v beta 3 integrin. Adhesion mechanism for transformed glial cells.
- 1998 Neurotumor Club. March 30, 1998, New Orleans, La.
- Transcriptional regulation of the human osteopontin promoter: functional analysis and DNA-protein interactions.
- p125 focal adhesion kinase promotes malignant astrocytoma cell proliferation in vivo.
- Extracellular FGF-1 inhibits cytoskeletal organization and promotes fibroblast motility.
- Attachment of primary neonatal rat astrocytes to vitronectin is mediated by integrins alphavbeta5 and alpha8beta1: modulation by the type 1 plasminogen activator inhib...
- Malignant astrocytoma cell attachment and migration to various matrix proteins is differentially sensitive to phosphoinositide 3-OH kinase inhibitors.
- TGF-beta1 up-regulates paxillin protein expression in malignant astrocytoma cells: requirement for a fibronectin substrate.
- HEF1 is a necessary and specific downstream effector of FAK that promotes the migration of glioblastoma cells.
Schools
Loyola University of Chicago Stritch School of Medicine
Loyola University Med Center
Scripps Clinic
UCLA Med Center
University Ca San Diego Med Center
Doctors Specialties
- Neuropathology
- Pathology
Accepted Insurances
Education
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University of California San Diego -
Scripps Clinic -
UCLA Medical Center -
Loyola University -
Loyola University Chicago Stritch School of Medicine
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