Associate Medical Examiner and Neuropathologist, Office of the Medical Examiner, City of Philadelphia, PA
Pathology
Dr. Bruce P. Wainer, MD
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Bruce Wainer is an expert in the field of Pathology. He graduated from University of Chicago Pritzker School of Medicine. University of Chicago Pritzker School of Medicine has a rank of 10 in research and a 19 in primary care He has 8 awards "Highly Cited Neuroscientist, Charter Member", "Scholars Award", "Alpha Omega Alpha", "Sheard, Sanford Award", "Sigma Xi", "Phi Beta Kappa", "Phi Sigma" and "Phi Sigma Award". Bruce P. Wainer is a published MD as well. He has 100 publications published. The latest was: Beta-adrenergic and fibroblast growth factor receptors induce neuronal process outgrowth through different mechanisms.
Publications
- A mutation of beta -actin that alters depolymerization dynamics is associated with autosomal dominant developmental malformations, deafness, and dystonia.
- Phosphatidylinositol-4-kinase type II alpha is a component of adaptor protein-3-derived vesicles.
- Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.
- AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells.
- Neuronal and glial pathological changes during epileptogenesis in the mouse pilocarpine model.
- Aggregation of actin and cofilin in identical twins with juvenile-onset dystonia.
- BLOC-1 complex deficiency alters the targeting of adaptor protein complex-3 cargoes.
- Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase.
- Effects of passive immunization against morphine on heroin self-administration.
- Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.
- Expression of glucocorticoid and mineralocorticoid receptors in an immortalized hippocampal neuronal cell line.
- Beta-adrenergic receptor activation promotes process outgrowth in an embryonic rat basal forebrain cell line and in primary neurons.
- Neural plasticity as studied in neuronal cell lines.
- Insulin gene expression in immortalized rat hippocampal and pheochromocytoma-12 cell lines.
- Ultrastructural study of cholinergic and noncholinergic neurons in the pars compacta of the rat pedunculopontine tegmental nucleus.
- Serotonergic dorsal raphe nucleus projections to the cholinergic and noncholinergic neurons of the pedunculopontine tegmental region: a light and electron microscopic ...
- Beta-adrenergic and fibroblast growth factor receptors induce neuronal process outgrowth through different mechanisms.
- Tau pathology in a family with dementia and a P301L mutation in tau.
- The specificity of antimorphine and antimeperidine antibodies and their reactivity with opioid peptides.
- Calcific stenosis of the porcine heterograft.
- Cellular aspects of trophic actions in the nervous system.
- Nerve growth factor, but not epidermal growth factor, increases Fra-2 expression and alters Fra-2/JunD binding to AP-1 and CREB binding elements in pheochromocytoma (P...
- Coupling of cAMP/PKA and MAPK signaling in neuronal cells is dependent on developmental stage.
- Tau-associated neuropathology in ganglion cell tumours increases with patient age but appears unrelated to ApoE genotype.
- Complications of gamma knife surgery for Parkinson disease.
- The interaction of morphine with sera from monkeys physically dependent on morphine.
- The production and characterization of antibodies reactive with meperidine.
- Delayed clearance of morphine from the circulation of rabbits immunized with morphine-6-hemisuccinate bovine serum albumin.
- Acetylcholine synthesis and release is enhanced by dibutyryl cyclic AMP in a neuronal cell line derived from mouse septum.
- Immortal rat hippocampal cell lines exhibit neuronal and glial lineages and neurotrophin gene expression.
- Cellular alterations produced by the experimental increase in intracellular calcium and the nature of protective effects from pretreatment with nimodipine.
- Specific modulation of dopamine expression in neuronal hybrid cells by primary cells from different brain regions.
- Stability of septohippocampal neurons following excitotoxic lesions of the rat hippocampus.
- Afferent projections to the cholinergic pedunculopontine tegmental nucleus and adjacent midbrain extrapyramidal area in the albino rat. I. Retrograde tracing studies.
- Expression of neurotrophins and the low-affinity NGF receptor in septal and hippocampal reaggregate cultures: local physiologic effects of NGF synthesized in the septa...
- Nerve growth factor expression in the developing hippocampus isolated in vitro.
- Distant angiogenesis in a patient with glioblastoma multiforme.
- In vitro cell cultures as a model of the basal forebrain.
- Constitutive expression of the mature array of neurofilament proteins by a CNS neuronal cell line.
- Immortalization of embryonic mesencephalic dopaminergic neurons by somatic cell fusion.
- Neuronal properties and trophic activities of immortalized hippocampal cells from embryonic and young adult mice.
- Ultrastructure of cholinergic synaptic terminals in the thalamic anteroventral, ventroposterior, and dorsal lateral geniculate nuclei of the rat.
- Immortalized young adult neurons from the septal region: generation and characterization.
- Development and characterization of clonal cell lines derived from septal cholinergic neurons.
- Galanin-like immunoreactivity in cholinergic neurons of the septum-basal forebrain complex projecting to the hippocampus of the rat.
- Colocalization of atriopeptin-like immunoreactivity with choline acetyltransferase- and substance P-like immunoreactivity in the pedunculopontine and laterodorsal tegm...
- A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride.
- Substance P-containing terminals in synaptic contact with cholinergic neurons in the neostriatum and basal forebrain: a double immunocytochemical study in the rat.
- Cholinergic nucleus basalis neurons may influence the cortex via the thalamus.
- The origins of cholinergic and other subcortical afferents to the thalamus in the rat.
- Axonal and transneuronal transport in the transmission of neurological disease: potential role in system degenerations, including Alzheimer''s disease.
- Medullary and spinal efferents of the pedunculopontine tegmental nucleus and adjacent mesopontine tegmentum in the rat.
- Cholinergic vs. noncholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei.
- Ascending projections from the pedunculopontine tegmental nucleus and the adjacent mesopontine tegmentum in the rat.
- Correlated light and electron microscopic study of dopaminergic neurons and their synaptic junctions with DARPP-32-containing cells in three-dimensional reaggregate ti...
- Stabilization of TMB reaction product for electron microscopic retrograde and anterograde fiber tracing.
- An atlas of the regional and laminar distribution of choline acetyltransferase immunoreactivity in rat cerebral cortex.
- The effects of nerve growth factor on the development of septal cholinergic neurons in reaggregate cell cultures.
- Neurotrophic factors and Alzheimer's disease.
- Pedunculopontine tegmental nucleus of the rat: cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum.
- Cortical effects of neurotoxic damage to the nucleus basalis in rats: persistent loss of extrinsic cholinergic input and lack of transsynaptic effect upon the number o...
- Cholinergic innervation displays strikingly different laminar preferences in several cortical areas.
- Ultrastructural evidence for hippocampal target cell-mediated trophic effects on septal cholinergic neurons in reaggregating cell cultures.
- Ultrastructure of ChAT-immunoreactive synaptic terminals in the thalamic reticular nucleus of the rat.
- Cholinergic projections from the laterodorsal and pedunculopontine tegmental nuclei to the pontine gigantocellular tegmental field in the cat.
- Immunohistochemistry of choline acetyltransferase in the guinea pig brain.
- Three-dimensional representation and cortical projection topography of the nucleus basalis (Ch4) in the macaque: concurrent demonstration of choline acetyltransferase ...
- Colocalization of gamma-aminobutyric acid and acetylcholinesterase in rodent cortical neurons.
- Choline acetyltransferase immunoreactivity in the rat thalamus.
- Fiber pathways of basal forebrain cholinergic neurons in monkeys.
- Neurotrophic effects of hippocampal target cells on developing septal cholinergic neurons in culture.
- NGF effects on developing forebrain cholinergic neurons are regionally specific.
- Cholinergic projections from the parabigeminal nucleus (Ch8) to the superior colliculus in the mouse: a combined analysis of horseradish peroxidase transport and choli...
- Neuronal properties of clonal hybrid cell lines derived from central cholinergic neurons.
- Basal forebrain neurons have axon collaterals that project to widely divergent cortical areas in the cat.
- Discrete distribution of cholinergic and vasoactive intestinal polypeptidergic amacrine cells in the rat retina.
- Evidence for the coexistence of acetylcholine and enkephalin in the sympathetic preganglionic neurons of rats.
- Cholinergic and non-cholinergic septohippocampal pathways.
- Immunoaffinity purification of human choline acetyltransferase: comparison of the brain and placental enzymes.
- A correlated light and electron microscopic study of identified cholinergic basal forebrain neurons that project to the cortex in the rat.
- Cholinergic neurons in the telencephalon of the reptile Caiman crocodilus.
- Immunochemical studies of opioids: specificities of antibodies against codeine and hydromorphone.
- Changes in heroin self-administration by a rhesus monkey after morphine immunisation.
- A measurement of the specificities of antibodies to morphine-6-succinyl-BSA by competitive inhibition of 14 C-morphine binding.
- In vitro morphine antagonism by antibodies.
- The interaction of 14C-morphine with sera from immunized rabbits and from patients addicted to heroin.
- Morphine-3-succinyl--bovine serum albumin: an immunogenic hapten-protein conjugate.
- The structure of morphine monohemisuccinate.
- The possible role of intracellular receptors in the expression of narcotic antagonist precipitated abstinence.
- Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).
- Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase.
- Co-localization of acetylcholinesterase and choline acetyltransferase in the rat cerebrum.
- Multiple isoelectric and molecular weight variants of choline acetyltransferase. Artifact or real?
- Retrograde horseradish peroxidase tracing combined with localization of choline acetyltransferase immunoreactivity.
- Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinest...
- Characterization of cholinergic neurons in the rat neostriatum. A combination of choline acetyltransferase immunocytochemistry, Golgi-impregnation and electron microsc...
- Choline acetyltransferase-like immunoreactivity in the forebrain of the red-eared pond turtle (Pseudemys scripta elegans).
- Cholinergic synapses in the rat brain: a correlated light and electron microscopic immunohistochemical study employing a monoclonal antibody against choline acetyltran...
- Evidence for cholinergic neurites in senile plaques.
Schools
Autonomous University of Ciudad Juarez
Brown University Meml Hospital
Suny Downstate Med Center
Doctors Specialties
- Internal Medicine
- Pathology
Accepted Insurances
Awards
- Highly Cited Neuroscientist, Charter Member
- Scholars Award
- Alpha Omega Alpha
- Sheard, Sanford Award
- Sigma Xi
- Phi Beta Kappa
- Phi Sigma
- Phi Sigma Award
Education
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University of Chicago -
University of Chicago Pritzker School of Medicine
Hospital
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Emory University Hospital
Drug Facts
| NPI NUMBER | 1962506204 | |
| NPPES Provider LastName | WAINER | |
| NPPES Provider FirstName | BRUCE | |
| NPPES Provider ZIPCode | 066145333 | |
| NPPES Provider State | CT | |
| Specialty Description | Internal Medicine | |
| Total Claim Count | 8757.0 | |
| Distinct Opioid Count | 3.0 | |
| Opioid Claim Count | 66.0 | |
| Percent Opioid Claims | 0.75 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1962506204 |
| Last Name Of The Provider | WAINER |
| First Name Of The Provider | BRUCE |
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