Assistant Professor, Pediatrics, UCLA School of Medicine

Pediatric Hematology & Oncology

Dr. Brigitte N. Gomperts, MD

Brigitte Gomperts practices Pediatric Hematology & Oncology. Brigitte Gomperts has written publications. She has 32 publications published with PubMed. The lastest publication is: 'Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling.'

Publications

Dynamic Changes in Intracellular ROS Levels Regulate Airway Basal Stem Cell Homeostasis through Nrf2-Dependent Notch Signaling.
Induction of multiciliated cells from induced pluripotent stem cells.
Aldehyde dehydrogenase activity enriches for proximal airway epithelial basal stem cells and promotes their proliferation.
MicroRNA 4423 is a primate-specific regulator of airway epithelial cell differentiation and lung carcinogenesis.
Enriching the molecular definition of the airway "field of Cancerization:" establishing new paradigms for the patient at risk for lung Cancer.
Isolation and in vitro characterization of Basal and submucosal gland duct stem/progenitor cells from human proximal airways.
Repair and regeneration of tracheal surface epithelium and submucosal glands in a mouse model of hypoxic-ischemic injury.
Novel stem/progenitor cell population from murine tracheal submucosal gland ducts with multipotent regenerative potential.
B-Acute lymphoblastic leukemia and cystinuria in a patient with duplication 22q11.21 detected by chromosomal microarray analysis.
Evolving concepts in lung carcinogenesis.
Presence of a putative tumor-initiating progenitor cell population predicts poor prognosis in smokers with non-small cell lung Cancer.
Lung Cancer biomarkers: FISHing in the sputum for risk assessment and early detection.
Quantification of cytokeratin 5 mRNA expression in the circulation of healthy human subjects and after lung transplantation.
IL-13 regulates cilia loss and foxj1 expression in human airway epithelium.
Fibrocytes in lung disease.
Keratinocyte growth factor improves repair in the injured tracheal epithelium.
The role of CXC chemokines in pulmonary fibrosis.
Stem cells and chronic lung disease.
IL-13 is pivotal in the fibro-obliterative process of bronchiolitis obliterans syndrome.
Circulating progenitor epithelial cells traffic via CXCR4/CXCL12 in response to airway injury.
CXCR2/CXCR2 ligand biology during lung transplant ischemia-reperfusion injury.
Differential recognition of secretory vesicles by annexins. European Molecular Biology Organization Course "Advanced Techniques for Studying Secretion".
Case 1: A limping child...with abdominal pain.
Role of CXCR2/CXCR2 ligands in vascular remodeling during bronchiolitis obliterans syndrome.
Cancer CXC chemokine networks and tumour angiogenesis.
Altered levels of CC chemokines during pulmonary CMV predict BOS and mortality post-lung transplantation.
CXC chemokines in angiogenesis.
Foxj1 regulates basal body anchoring to the cytoskeleton of ciliated pulmonary epithelial cells.
Gonococcal hand abscess.
Chemokine-directed metastasis.
Circulating progenitor cells in chronic lung disease.

Schools

University Of The Witwatersrand Faculty Of Health Sciences

Conditions Treated

Acute Leukemia
Anemia
Brain and Nervous System Cancer (incl. Gliomas, Astrocytoma, Schwannoma, Medulloblastoma, Chordoma)
Brain Cancer
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Doctors Specialties

Pediatric Hematology
Oncology

Accepted Insurances

Education

Washington University
University of the Witwatersrand

Hospital

Mattel Children's Hospital UCLA
Ronald Reagan UCLA Medical Center
Santa Monica-UCLA Medical Center and Orthopaedic Hospital

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