Associate Professor of Medicine, Beth Israel Deaconess Medical Center
Nephrology
Dr. Bradley M. Denker, MD
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Bradley Denker is an expert in the field of Nephrology. He graduated from State University of New York Upstate Medical University. He has 2 awards "CMS Meaningful Use Stage 1 Certification" and "Super Doctor". Bradley M. Denker, MD is a published doctor and has 20 publications published. The lastest was: 'Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in kidney epithelial cells.' Doctor Bradley M. Denker, MD accepts Medicare payments and is registered with Medicare.gov.
Publications
- Polycystin-1 and Gα12 regulate the cleavage of E-cadherin in Kidney epithelial cells.
- G?12 activation in podocytes leads to cumulative changes in glomerular collagen expression, Proteinuria and glomerulosclerosis.
- Primary care management of chronic Kidney disease.
- The biology of epithelial cell tight junctions in the Kidney.
- Identification of an antithrombotic allosteric modulator that acts through helix 8 of PAR1.
- Regulation of integrin expression by Gα12: An additional potential mechanism modulating cell attachment.
- Polycystin-1 protein level determines activity of the Galpha12/JNK apoptosis pathway.
- G alpha 12 inhibits alpha2 beta1 integrin-mediated Madin-Darby canine Kidney cell attachment and migration on collagen-I and blocks tubulogenesis.
- Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinity.
- Galpha12 stimulates apoptosis in epithelial cells through JNK1-mediated Bcl-2 degradation and up-regulation of IkappaBalpha.
- Domains necessary for Galpha12 binding and stimulation of protein phosphatase-2A (PP2A): Is Galpha12 a novel regulatory subunit of PP2A?
- Cell-cell interactions in the Kidney: inducible expression of mutant G protein alpha-subunits in Madin-Darby canine Kidney cells for studies of epithelial cell junctio...
- Cultured podocytes establish a size-selective barrier regulated by specific signaling pathways and demonstrate synchronized barrier assembly in a Calcium switch model ...
- Galpha12 directly interacts With PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.
- Polycystin-1L2 is a novel G-protein-binding protein.
- Alpha-actinin-4-mediated FSGS: an inherited Kidney disease caused by an aggregated and rapidly degraded cytoskeletal protein.
- Galpha12 regulates epithelial cell junctions through Src tyrosine kinases.
- Association and colocalization of G protein alpha subunits and Purkinje cell protein 2 (Pcp2) in mammalian cerebellum.
- Zonula occludens-1 is a scaffolding protein for signaling molecules. Galpha(12) directly binds to the Src homology 3 domain and regulates paracellular permeability in ...
Schools
SUNY Upstate Medical University Syracuse
Johns Hopkins Hospital
Johns Hopkins
Brigham and Women39s Hospital
Procedures Preformed
- Hemodialysis
- Peritoneal Dialysis
Conditions Treated
- Acidosis
- Acute Glomerulonephritis
- Acute Kidney Failure
- Calcium Metabolism Disorders
- View All
Doctors Specialties
- Nephrology
Accepted Insurances
Awards
- CMS Meaningful Use Stage 1 Certification
- Super Doctor
Education
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Brigham and Women's Hospital -
Johns Hopkins University -
State University of New York Upstate Medical University
Hospital
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Beth Israel Deaconess Medical Center -
Newton-Wellesley Hospital -
Brigham and Women's Faulkner Hospital -
Brigham and Women's Hospital
Drug Facts
| NPI NUMBER | 1669438727 | |
| NPPES Provider LastName | DENKER | |
| NPPES Provider FirstName | BRADLEY | |
| NPPES Provider ZIPCode | 022153904 | |
| NPPES Provider State | MA | |
| Specialty Description | Nephrology | |
| Total Claim Count | 670.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 32.0 | |
| Percent Opioid Claims | 4.78 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1669438727 |
| Last Name Of The Provider | DENKER |
| First Name Of The Provider | BRADLEY |
| View All |
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