Physician
Internal Medicine
Dr. Bradford W. Gibson, MD
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Bradford W. Gibson works in the field of Internal Medicine. He attended University of Kentucky College of Medicine. University of Kentucky College of Medicine is ranked 63 in research and 72 in primary care medicine Bradford Gibson is also a published MD. He has 101 paper published. The most recent paper is: The lipooligosaccharides of Haemophilus ducreyi are highly sialylated. Bradford Gibson is registered with Medicare.
Publications
- Wavelet-Based Peak Detection and a New Charge Inference Procedure for MS/MS Implemented in ProteoWizard's msConvert.
- Iron promotes protein insolubility and aging in C. elegans.
- The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites.
- Panorama: a targeted proteomics knowledge base.
- RPL24: a potential therapeutic target whose depletion or acetylation inhibits polysome assembly and cancer cell growth.
- Variation and quantification among a target set of phosphopeptides in human plasma by multiple reaction monitoring (MRM) and SWATH MS2 data-independent acquisition.
- A framework for installable external tools in Skyline.
- Phosphoprotein secretome of tumor cells as a source of candidates for breast cancer biomarkers in plasma.
- Francisella tularensis Schu S4 Lipopolysaccharide Core Sugar and O-Antigen Mutants Are Attenuated in a Mouse Model of Tularemia.
- Sirtuin 3 (SIRT3) Protein Regulates Long-chain Acyl-CoA Dehydrogenase by Deacetylating Conserved Lysines Near the Active Site.
- Design, Implementation and Multisite Evaluation of a System Suitability Protocol for the Quantitative Assessment of Instrument Performance in Liquid Chromatography-Mul...
- Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures.
- Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
- The O-antigen and core carbohydrate of Vibrio fischeri lipopolysaccharide: Composition and analysis of their role in Euprymna scolopes light organ colonization.
- Regulatory control or oxidative damage? Proteomic approaches to interrogate the role of cysteine oxidation status in biological processes.
- Proteomic analysis of age-dependent changes in protein solubility identifies genes that modulate lifespan.
- Life span extension via eIF4G inhibition is mediated by posttranscriptional remodeling of stress response gene expression in C. elegans.
- Mass spectrometric identification of novel lysine acetylation sites in huntingtin.
- The lipid A from Vibrio fischeri lipopolysaccharide: A unique structure bearing a phosphoglycerol moiety.
- Confident identification of 3-nitrotyrosine modifications in mass spectral data across multiple mass spectrometry platforms.
- Quantitative mapping of reversible mitochondrial Complex I cysteine oxidation in a Parkinson disease mouse model.
- A lectin affinity workflow targeting glycosite-specific, cancer-related carbohydrate structures in trypsin-digested human plasma.
- Identification of new modulators and protein alterations in non-apoptotic programmed cell death.
- Targeted quantitation of site-specific cysteine oxidation in endogenous proteins using a differential alkylation and multiple reaction monitoring mass spectrometry app...
- ErbB2 trafficking and degradation associated with K48 and K63 polyubiquitination.
- Repeatability and reproducibility in proteomic identifications by liquid chromatography-tandem mass spectrometry.
- Interlaboratory study characterizing a yeast performance standard for benchmarking LC-MS platform performance.
- Performance metrics for liquid chromatography-tandem mass spectrometry systems in proteomics analyses.
- Sweetening the pot: adding glycosylation to the biomarker discovery equation.
- Identification, characterization and immunogenicity of an O-antigen capsular polysaccharide of Francisella tularensis.
- The Mycobacterium bovis bacille Calmette-Guerin phagosome proteome.
- Preferentially increased nitration of alpha-synuclein at tyrosine-39 in a cellular oxidative model of Parkinson's disease.
- Calpain-1 cleaves and activates caspase-7.
- IDPicker 2.0: Improved protein assembly with high discrimination peptide identification filtering.
- Multi-site assessment of the precision and reproducibility of multiple reaction monitoring-based measurements of proteins in plasma.
- Systematic mapping of posttranslational modifications in human estrogen receptor-alpha with emphasis on novel phosphorylation sites.
- A lectin HPLC method to enrich selectively-glycosylated peptides from complex biological samples.
- A novel serine phosphorylation site detected in the N-terminal domain of estrogen receptor isolated from human breast cancer cells.
- Partial acetylation of lysine residues improves intraprotein cross-linking.
- Characterization of htrB and msbB mutants of the light organ symbiont Vibrio fischeri.
- Characterization of the N-acetyl-5-neuraminic acid-binding site of the extracytoplasmic solute receptor (SiaP) of nontypeable Haemophilus influenzae strain 2019.
- Identification of LpxL, a late acyltransferase of Francisella tularensis.
- Quantification of cysteine oxidation in human estrogen receptor by mass spectrometry.
- Characterization of lipid A acylation patterns in Francisella tularensis, Francisella novicida, and Francisella philomiragia using multiple-stage mass spectrometry and...
- Identification of genes involved in the expression of atypical lipooligosaccharide structures from a second class of Haemophilus ducreyi.
- Role of lgtC in resistance of nontypeable Haemophilus influenzae strain R2866 to human serum.
- Huntingtin phosphorylation sites mapped by mass spectrometry. Modulation of cleavage and toxicity.
- Novel pathways associated with quinone-induced stress in breast cancer cells.
- Biochemical and functional characterization of membrane blebs purified from Neisseria meningitidis serogroup B.
- Identification of a novel sialic acid transporter in Haemophilus ducreyi.
- Novel sialic acid transporter of Haemophilus influenzae.
- Characterization of a cluster of three glycosyltransferase enzymes essential for Moraxella catarrhalis lipooligosaccharide assembly.
- Rapid purification and mass spectrometric characterization of mitochondrial NADH dehydrogenase (Complex I) from rodent brain and a dopaminergic neuronal cell line.
- Novel modification of lipid A of Francisella tularensis.
- Expanded coverage of the human heart mitochondrial proteome using multidimensional liquid chromatography coupled with tandem mass spectrometry.
- Exploiting proteomics in the discovery of drugs that target mitochondrial oxidative damage.
- The Streptococcus gordonii platelet binding protein GspB undergoes glycosylation independently of export.
- Proteomic and immunochemical characterization of a role for stathmin in adult neurogenesis.
- Molecular components of a cell death pathway activated by endoplasmic reticulum stress.
- Identification of a 3-deoxy-D-manno-octulosonic acid biosynthetic operon in Moraxella catarrhalis and analysis of a KdsA-deficient isogenic mutant.
- Phosphospecific proteolysis for mapping sites of protein phosphorylation.
- Proteome of Haemophilus ducreyi by 2-D SDS-PAGE and mass spectrometry: strain variation, virulence, and carbohydrate expression.
- MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides.
- Primary sequence characterization of catestatin intermediates and peptides defines proteolytic cleavage sites utilized for converting chromogranin a into active catest...
- Metabolic incorporation of unnatural sialic acids into Haemophilus ducreyi lipooligosaccharides.
- Characterization of the human heart mitochondrial proteome.
- The msbB mutant of Neisseria meningitidis strain NMB has a defect in lipooligosaccharide assembly and transport to the outer membrane.
- Identification and characterization of the N-acetylglucosamine glycosyltransferase gene of Haemophilus ducreyi.
- An alternative strategy to determine the mitochondrial proteome using sucrose gradient fractionation and 1D PAGE on highly purified human heart mitochondria.
- The lbgAB gene cluster of Haemophilus ducreyi encodes a beta-1,4-galactosyltransferase and an alpha-1,6-DD-heptosyltransferase involved in lipooligosaccharide biosynth...
- Characterization of lipooligosaccharides from Haemophilus ducreyi containing polylactosamine repeats.
- Haemophilus influenzae type b strain A2 has multiple sialyltransferases involved in lipooligosaccharide sialylation.
- Intracellular survival of Neisseria gonorrhoeae in male urethral epithelial cells: importance of a hexaacyl lipid A.
- Targeted quantitation of acetylated lysine peptides by selected reaction monitoring mass spectrometry.
- Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.
- Regulation of sialic acid transport and catabolism in Haemophilus influenzae.
- Proposed second class of Haemophilus ducreyi strains show altered protein and lipooligosaccharide profiles.
- Proteomic analysis of plasma membrane and secretory vesicles from human neutrophils.
- Proteomic analysis of succinate dehydrogenase and ubiquinol-cytochrome c reductase (Complex II and III) isolated by immunoprecipitation from bovine and mouse heart mit...
- N-acylethanolamine signalling mediates the effect of diet on lifespan in Caenorhabditis elegans.
- Utilizing the O-antigen lipopolysaccharide biosynthesis pathway in Escherichia coli to interrogate the substrate specificities of exogenous glycosyltransferase genes i...
- Small-scale immunopurification of cytochrome c oxidase for a high-throughput multiplexing analysis of enzyme activity and amount.
- DAF-12-dependent rescue of dauer formation in Caenorhabditis elegans by (25S)-cholestenoic acid.
- Stable isotope metabolic labeling of Neisseria meningitidis lipooligosaccharide.
- Mass spectrometric identification of a novel phosphorylation site in subunit NDUFA10 of bovine mitochondrial complex I.
- The human mitochondrial proteome: oxidative stress, protein modifications and oxidative phosphorylation.
- Lipophilic regulator of a developmental switch in Caenorhabditis elegans.
- Matrix-assisted laser desorption/ionization-time of flight-mass spectrometry of lipopolysaccharide species separated by slab-polyacrylamide gel electrophoresis: high-r...
- Nontypeable Haemophilus influenzae strain 2019 produces a biofilm containing N-acetylneuraminic acid that may mimic sialylated O-linked glycans.
- Structural studies of the lipooligosaccharides from Haemophilus influenzae type b strain A2.
- The lipooligosaccharides of Haemophilus ducreyi are highly sialylated.
- Analysis of peptides and proteins containing nitrotyrosine by matrix-assisted laser desorption/ionization mass spectrometry.
- Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter.
- Characterization of chimeric lipopolysaccharides from Escherichia coli strain JM109 transformed with lipooligosaccharide synthesis genes (lsg) from Haemophilus influen...
- Cloning and characterization of the lipooligosaccharide galactosyltransferase II gene of Haemophilus ducreyi.
- High throughput protein fold identification by using experimental constraints derived from intramolecular cross-links and mass spectrometry.
- Construction and characterization of Haemophilus ducreyi lipooligosaccharide (LOS) mutants defective in expression of heptosyltransferase III and beta1,4-glucosyltrans...
- Non-typeable Haemophilus influenzae adhere to and invade human bronchial epithelial cells via an interaction of lipooligosaccharide with the PAF receptor.
- Lipooligosaccharide P(k) (Galalpha1-4Galbeta1-4Glc) epitope of moraxella catarrhalis is a factor in resistance to bactericidal activity mediated by normal human serum.
- Biosynthesis of sialylated lipooligosaccharides in Haemophilus ducreyi is dependent on exogenous sialic acid and not mannosamine. Incorporation studies using N-acylman...
Schools
Medical College of Georgia
Doctors Specialties
- Internal Medicine
Accepted Insurances
Education
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University of Kentucky College of Medicine
Hospital
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Northside Hospital
Drug Facts
| NPI NUMBER | 1922296458 | |
| NPPES Provider LastName | GIBSON | |
| NPPES Provider FirstName | BRADFORD | |
| NPPES Provider ZIPCode | 403511179 | |
| NPPES Provider State | KY | |
| Specialty Description | Internal Medicine | |
| Total Claim Count | 300.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1922296458 |
| Last Name Of The Provider | GIBSON |
| First Name Of The Provider | BRADFORD |
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