Physician
General Surgery
Dr. Bernard S. Shapiro, MD
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Bernard Shapiro practices General Surgery. He attended University at Buffalo, School of Medicine and Biomedical Sciences. He has 1 awards "Fellow (FACS)". Bernard Shapiro has written publications. He has 50 publications published with PubMed. The lastest paper is: 'Interactions of gender, growth hormone, and phenobarbital induction on murine Cyp2b expression.'
Publications
- Permanent uncoupling of male-specific CYP2C11 transcription/translation by perinatal glutamate.
- Irreversible perinatal imprinting of adult expression of the principal sex-dependent drug-metabolizing enzyme CYP2C11.
- Growth hormone regulation of hepatic drug-metabolizing enzymes in the mouse.
- Subnormal concentrations in the feminine profile of circulating growth hormone enhance expression of female-specific CYP2C12.
- Feminization of hepatic cytochrome P450s by nominal levels of growth hormone in the feminine plasma profile.
- Irreversible suppression of growth hormone-dependent cytochrome P450 2C11 in adult rats neonatally treated with monosodium glutamate.
- Effects of neonatally administered monosodium glutamate on the sexually dimorphic profiles of circulating growth hormone regulating murine hepatic monooxygenases.
- Signalling elements in the ultradian rhythm of circulating growth hormone regulating expression of sex-dependent forms of hepatic cytochrome P450.
- Renaturalizing the sexually dimorphic profiles of circulating growth hormone in hypophysectomized rats.
- Gender differences in drug metabolism regulated by growth hormone.
- Simulataneous isolation of NADPH-cytochrome P-450 reductase and cytochrome P-450 using tentacle ion-exchange chromatography and interspecies comparison of the reductas...
- Sex- and dose-dependent effects of neonatally administered aspartate on the ultradian patterns of circulating growth hormone regulating hexobarbital metabolism and act...
- Over-expression of CYP2C11, the major male-specific form of hepatic cytochrome P450, in the presence of nominal pulses of circulating growth hormone in adult male rats...
- Neonatal phenobarbital-induced defects in age- and sex-specific growth hormone profiles regulating monooxygenases.
- Neonatal phenobarbital-induced persistent alterations in plasma testosterone profiles and testicular function.
- Gender differences in the responsiveness of the sex-dependent isoforms of hepatic P450 to the feminine plasma growth hormone profile.
- Nominal growth hormone pulses in otherwise normal masculine plasma profiles induce intron retention of overexpressed hepatic CYP2C11 with associated nuclear splicing d...
- Intrinsic signals in the sexually dimorphic circulating growth hormone profiles of the rat.
- Epidermal growth factor regulation of female-dependent CYP2A1 and CYP2C12 in primary rat hepatocyte culture.
- Infusion of gender-dependent plasma growth hormone profiles into intact rats: effects of subcutaneous, intraperitoneal, and intravenous routes of rat and human growth ...
- Latent overexpression of hepatic CYP2C7 in adult male and female rats neonatally exposed to phenobarbital: a developmental profile of gender-dependent P450s.
- Differential expression of gender-dependent hepatic isoforms of cytochrome P-450 by pulse signals in the circulating masculine episodic growth hormone profile of the rat.
- Interactions of gender, growth hormone, and phenobarbital induction on murine Cyp2b expression.
- A comparison of cytochrome P450-dependent testosterone 2alpha-hydroxylase in rat (P4502C11) and mouse (P4502alpha).
- Gender, age and dose effects of neonatally administered aspartate on the sexually dimorphic plasma growth hormone profiles regulating expression of the rat sex-depende...
- Imprinted overinduction of hepatic CYP2B1 and 2B2 in adult rats neonatally exposed to phenobarbital.
- Purification and characterization of constituent androstenedione 15 alpha-hydroxylase (cytochrome P450(15 alpha AD)) from mouse liver. Sex- and tissue-dependent expres...
- Phenobarbital induction of hepatic CYP2B1 and CYP2B2: pretranscriptional and post-transcriptional effects of gender, adult age, and phenobarbital dose.
- Differential effects of neonatally administered glutamate on the ultradian pattern of circulating growth hormone regulating expression of sex-dependent forms of cytoch...
- Intrasplenic Transplantation of Isolated Adult Rat Hepatocytes: Sex-Reversal and/or Suppression of the Major Constituent Isoforms of Cytochrome P450.
- Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in ...
- Inherent sexually dimorphic expression of hepatic CYP2C12 correlated with repressed activation of growth hormone-regulated signal transduction in male rats.
- Sex-dependent expression of CYP2C11 in spleen, thymus and bone marrow regulated by growth hormone.
- Attenuated expression of episodic growth hormone-induced CYP2C11 in female rats associated with suboptimal activation of the Jak2/Stat5B and other modulating signaling...
- Effect of perinatal low protein diets on the ontogeny of select hepatic cytochrome p450 enzymes and cytochrome p450 reductase in the rat.
- A molecular basis for the sexually dimorphic response to growth hormone.
- Two low protein diets differentially affect food consumption and reproductive performance in pregnant and lactating rats and long-term growth in their offspring.
- Sex-dependent expression of seven housekeeping genes in rat liver.
- Inducibility of male-specific isoforms of cytochrome p450 by sex-dependent growth hormone profiles in hepatocyte cultures from male but not female rats.
- Sexually dimorphic regulation of hepatic isoforms of human cytochrome p450 by growth hormone.
- Neonatal phenobarbital imprints overexpression of cytochromes P450 with associated increase in tumorigenesis and reduced life span.
- Inadequacy of the Janus kinase 2/signal transducer and activator of transcription signal transduction pathway to mediate episodic growth hormone-dependent regulation o...
- Intrinsic sex differences determine expression of growth hormone-regulated female cytochrome P450s.
- Interpulse growth hormone secretion in the episodic plasma profile causes the sex reversal of cytochrome P450s in senescent male rats.
- Spurious observation of splenic cyp2b1 expression.
- Phenobarbital-imprinted overinduction of adult constituent CYP isoforms.
- Constitutive and inducible hepatic cytochrome P450 isoforms in senescent male and female rats and response to low-dose phenobarbital.
- Prevention of latently expressed CYP2C11, CYP3A2, and growth hormone defects in neonatally monosodium glutamate-treated male rats by the N-methyl-D-aspartate receptor ...
- Middle-age alterations in the sexually dimorphic plasma growth hormone profiles: involvement of growth hormone-releasing factor and effects on cytochrome p450 expression.
Schools
State University of New York At Buffalo
Doctors Specialties
- General Surgery
Accepted Insurances
Awards
- Fellow (FACS)
Education
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Albert Einstein - Montefiore Medical Center -
University at Buffalo, School of Medicine and Biomedical Sciences
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