Physician

Pulmonology

Bernadette R. Gochuico is an expert in the field of Pulmonology. She researched medicine at Boston University School of Medicine. Boston University School of Medicine is ranked 30/52 in Research/PrimaryCare. Bernadette R. Gochuico is a published doctor and has 41 publications published. The lastest was: 'Airway epithelial Fas ligand expression: potential role in modulating bronchial inflammation.'

Publications

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• In vitro functional correction of Hermansky-Pudlak Syndrome type-1 by lentiviral-mediated gene transfer.
• Transforming Growth Factor-β1 Downregulates Vascular Endothelial Growth Factor-D Expression in Human Lung Fibroblasts via JNK Signaling Pathway.
• Nuclear Localization of VEGF-D and Regulation of c-Myc-Dependent Transcripts in Human Lung Fibroblasts.
• Dysregulation of Galectin-3: Implications for Hermansky-Pudlak Syndrome Pulmonary Fibrosis.
• Syndecan-2 Exerts Antifibrotic Effects by Promoting Caveolin-1-mediated Transforming Growth Factor-β Receptor I Internalization and Inhibiting Transforming Growth Fact...
• Identification of citrullinated heat shock protein 90 isoforms as novel autoantigens in rheumatoid arthritis-associated interstitial lung disease.
• Interstitial Lung Disease and Pulmonary Fibrosis in Hermansky-Pudlak Syndrome Type 2, an AP-3 Complex Disease.
• Circulating markers of interstitial lung disease and subsequent risk of lung cancer.
• Prevalence of uterine leiomyomas in lymphangioleiomyomatosis.
• Clinical, Molecular, and Cellular Features of Non-Puerto Rican Hermansky-Pudlak Syndrome Patients of Hispanic Descent.
• Early alveolar epithelial dysfunction promotes lung inflammation in a mouse model of Hermansky-Pudlak syndrome.
• Automated Quantification of HRCT Findings in Individuals at Risk for Pulmonary Fibrosis.
• Natural history of pulmonary fibrosis in two subjects with the same telomerase mutation.
• Pirfenidone for the treatment of Hermansky-Pudlak syndrome pulmonary fibrosis.
• Erythropoietin-driven proliferation of cells with mutations in the tumor suppressor gene TSC2.
• The HLA class II Allele DRB1*1501 is over-represented in patients with idiopathic pulmonary fibrosis.
• Epithelial stress and apoptosis underlie Hermansky-Pudlak syndrome-associated interstitial pneumonia.
• Bleomycin and IL-1beta-mediated pulmonary fibrosis is IL-17A dependent.
• Alveolar macrophage dysregulation in Hermansky-Pudlak syndrome type 1.
• ADP-ribosylation of human defensin HNP-1 results in the replacement of the modified arginine with the noncoded amino acid ornithine.
• Characterization and peripheral blood biomarker assessment of anti-Jo-1 antibody-positive interstitial lung disease.
• Abnormal lymphangiogenesis in idiopathic pulmonary fibrosis with insights into cellular and molecular mechanisms.
• Oxidative stress alters syndecan-1 distribution in lungs with pulmonary fibrosis.
• MMP1 and MMP7 as potential peripheral blood biomarkers in idiopathic pulmonary fibrosis.
• Progressive preclinical interstitial lung disease in rheumatoid arthritis.
• Early interstitial lung disease in familial pulmonary fibrosis.
• Impairment of alveolar macrophage transcription in idiopathic pulmonary fibrosis.
• ADP-ribosyltransferase-specific modification of human neutrophil peptide-1.
• Atherosclerotic plaque macrophage transcriptional regulators are expressed in blood and modulated by tristetraprolin.
• Peribronchiolar metaplasia: a common histologic lesion in diffuse lung disease and a rare cause of interstitial lung disease: clinicopathologic features of 15 cases.
• Mononuclear Phagocytes and Airway Epithelial Cells: Novel Sources of Matrix Metalloproteinase-8 (MMP-8) in Patients with Idiopathic Pulmonary Fibrosis.
• Usual interstitial pneumonitis responsive to corticosteroids following varicella pneumonia.
• Potential pathogenesis and clinical aspects of pulmonary fibrosis associated with rheumatoid arthritis.
• Erdheim-Chester disease: a rare multisystem histiocytic disorder associated with interstitial lung disease.
• TRAIL expression in vascular smooth muscle.
• Airway epithelial Fas ligand expression: potential role in modulating bronchial inflammation.
• Fas expression in pulmonary alveolar type II cells.
• Simultaneous in situ hybridization and TUNEL to identify cells undergoing apoptosis.
• Acute fibrinous and organizing pneumonia: a histological pattern of lung injury and possible variant of diffuse alveolar damage.
• Effect of pirfenidone on the pulmonary fibrosis of Hermansky-Pudlak syndrome.

Schools

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• Boston University School Of Medicine

• Northwestern Meml Hospital

• Boston University Med Center

Doctors Specialties

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• Critical Care Medicine
• Pulmonology

Accepted Insurances

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Education

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• Boston University Medical Center
• McGaw Medical Center of Northwestern University
• Boston University School of Medicine

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