Professor, Pediatrics, University of Virginia School of Medicine
Pediatric Pulmonology
Dr. Benjamin M. Gaston, MD
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Benjamin Gaston is an expert in the field of Pediatric Pulmonology. He studied medicine at University of Virginia School of Medicine. He received awards:"Regional Top Doctor". Benjamin Gaston has written publications. He has 98 publications published with PubMed. The lastest publication is: 'Vital capacity reservoir and online measurement of childhood nitrosopnea are linearly related. Clinical implications.'
Publications
- Augmentation of CFTR maturation by S-nitrosoglutathione reductase.
- Detection of s-nitroso compounds by use of midinfrared cavity ring-down spectroscopy.
- Novel Approaches for Potential Therapy of Cystic Fibrosis.
- Phenotype of asthmatics with increased airway S-nitrosoglutathione reductase activity.
- Gene Expression in Relation to Exhaled NO Identifies Novel Asthma Phenotypes with Unique Biomolecular Pathways.
- Role of nitric oxide-containing factors in the ventilatory and cardiovascular responses elicited by hypoxic challenge in isoflurane-anesthetized rats.
- Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data.
- S-nitrosothiols increases cystic fibrosis transmembrane regulator expression and maturation in the cell surface.
- Low-dose morphine elicits ventilatory excitant and depressant responses in conscious rats: Role of peripheral μ-opioid receptors.
- l-Cysteine ethyl ester reverses the deleterious effects of morphine on, arterial blood-gas chemistry in tracheotomized rats.
- Hypoxia-induced ventilatory responses in conscious mice: Gender differences in ventilatory roll-off and facilitation.
- An Association between L-Arginine/Asymmetric Dimethyl Arginine Balance, Obesity, and the Age of Asthma Onset Phenotype.
- Ventilatory responses during and following exposure to a hypoxic challenge in conscious mice deficient or null in S-nitrosoglutathione reductase.
- Endothelial cell expression of haemoglobin α regulates nitric oxide signalling.
- Severe Asthma: Lessons Learned from the NHLBI Severe Asthma Research Program.
- Increased systemic inflammation overnight correlates with insulin resistance among children evaluated for obstructive sleep apnea.
- A neonatal mouse model of intestinal perforation: investigating the harmful synergism between glucocorticoids and indomethacin.
- Exhaled-breath condensate pH can be safely and continuously monitored in mechanically ventilated patients.
- S-nitrosylation signaling in cell biology.
- Nitrogen chemistry and lung physiology.
- The biology of nitrogen oxides in the airways.
- Nitric oxide synthase in human and rat lung: immunocytochemical and histochemical localization.
- Constitutive and inducible nitric oxide synthase gene expression, regulation, and activity in human lung epithelial cells.
- S-Nitrosylation of mitochondrial caspases.
- The effect of S-nitrosoglutathione and L-cysteine on chloride efflux from cystic fibrosis airway epithelial cells.
- Breath condensate analysis: perhaps worth studying, after all.
- Anaerobic killing of mucoid Pseudomonas aeruginosa by acidified nitrite derivatives under cystic fibrosis airway conditions.
- NO and nitrosothiols: spatial confinement and free diffusion.
- S-Nitrosoglutathione induces functional DeltaF508-CFTR in airway epithelial cells.
- Predicting intermediate phenotypes in asthma using bronchoalveolar lavage-derived cytokines.
- Endogenous nitric oxide in allergic airway disease.
- Inhaled budesonide in acute asthma?
- The C11orf30-LRRC32 region is associated with total serum IgE levels in asthmatic patients.
- Rethinking doctrine: bronchitis, eosinophils, and bronchoscopy in pediatric asthma.
- IL4R alpha mutations are associated with asthma exacerbations and mast cell/IgE expression.
- S-Nitrosothiol deficiency in asthma.
- Chemical regulation of pulmonary airway tone.
- Reductive assays for S-nitrosothiols: implications for measurements in biological systems.
- S-nitrosothiol depletion in amyotrophic lateral sclerosis.
- Inhaled corticosteroid dose reduction in childhood asthma: is nitrosopnea informative?
- Detecting physiologic fluctuations in the S-nitrosohemoglobin micropopulation: Triiodide versus 3C.
- S-Nitrosothiol measurements in biological systems.
- Transnitrosation signals oxyhemoglobin desaturation.
- S-nitrosoglutathione reductase in human lung cancer.
- Hsp 70/Hsp 90 organizing protein as a nitrosylation target in cystic fibrosis therapy.
- Nitric oxide in health and disease of the respiratory system.
- Lung function test results in normal infants: a COPSAC sequel.
- Decreased levels of nitrosothiols in the lower airways of patients with cystic fibrosis and normal pulmonary function.
- Correlation of systemic superoxide dismutase deficiency to airflow obstruction in asthma.
- Expired nitric oxide levels during treatment of acute asthma.
- S-nitrosothiols signal the ventilatory response to hypoxia.
- Mast cell phenotype, location, and activation in severe asthma. Data from the Severe Asthma Research Program.
- Alterations of the arginine metabolome in asthma.
- Vital capacity reservoir and online measurement of childhood nitrosopnea are linearly related. Clinical implications.
- Nitric oxide and thiol groups.
- Functional genomics and proteomics in control of breathing.
- SNOR and wheeze: the asthma enzyme?
- Condensed expirate nitrite as a home marker for acute asthma.
- Managing asthmatic airway inflammation: what is the role of expired nitric oxide measurement?
- Sickle cell disease does not decrease pulmonary nitric oxide.
- Accelerated s-nitrosothiol breakdown by amyotrophic lateral sclerosis mutant copper,zinc-superoxide dismutase.
- Acid-base equilibrium in exhaled breath condensate of allergic asthmatic children.
- Nitric oxide during altitude acclimatization.
- Use of exhaled nitric oxide measurement to identify a reactive, at-risk phenotype among patients with asthma.
- How acidopneic is my patient? A new question in the pulmonary laboratory.
- Summary: systemic effects of inhaled nitric oxide.
- Acid stress in the pathology of asthma.
- Identification of asthma phenotypes using cluster analysis in the Severe Asthma Research Program.
- Nitrogen redox balance in the cystic fibrosis airway: effects of antipseudomonal therapy.
- Airway acidification and gastroesophageal reflux.
- S-nitrosothiols regulate cell-surface pH buffering by airway epithelial cells during the human immune response to rhinovirus.
- S-nitrosoglutathione breakdown prevents airway smooth muscle relaxation in the guinea pig.
- NO chemical events in the human airway during the immediate and late antigen-induced asthmatic response.
- S-nitrosothiol formation.
- Importance of hedgehog interacting protein and other lung function genes in asthma.
- Obesity and asthma: An association modified by age of asthma onset.
- Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity.
- Bronchodilator S-nitrosothiol deficiency in asthmatic respiratory failure.
- Functional regulation of T-type calcium channels by s-nitrosothiols in the rat thalamus.
- Expired nitric oxide in pediatric asthma: emissions testing for children?
- Safety of investigative bronchoscopy in the Severe Asthma Research Program.
- Tumor necrosis factor-alpha from resident lung cells is a key initiating factor in pulmonary ischemia-reperfusion injury.
- S-nitrosothiol assays that avoid the use of iodine.
- Hemoglobin conformation couples erythrocyte S-nitrosothiol content to O2 gradients.
- Measurements of exhaled nitric oxide in healthy subjects age 4 to 17 years.
- Acute effects of aerosolized S-nitrosoglutathione in cystic fibrosis.
- Endogenous airway acidification. Implications for asthma pathophysiology.
- Determinants of exhaled breath condensate pH in a large population with asthma.
- Akt-mediated activation of HIF-1 in pulmonary vascular endothelial cells by S-nitrosoglutathione.
- S-nitrosoglutathione increases cystic fibrosis transmembrane regulator maturation.
- Tracheal aspirate pH is alkaline in pre-term human infants.
- Exhaled breath condensate: methodological recommendations and unresolved questions.
- S-nitrosothiols signal hypoxia-mimetic vascular pathology.
- Normoxic stabilization of hypoxia-inducible factor-1 expression and activity: redox-dependent effect of nitrogen oxides.
- Characterization of the severe asthma phenotype by the National Heart, Lung, and Blood Institute''s Severe Asthma Research Program.
- Expression and activity of pH-regulatory glutaminase in the human airway epithelium.
- Endogenous S-nitrosoglutathione modifies 5-lipoxygenase expression in airway epithelial cells.
Schools
Virginia Commonwealth University School Of Medicine
National Naval Med Center
Boston Chldns Hospital
Doctors Specialties
- Pediatric Pulmonology
Accepted Insurances
Awards
- Regional Top Doctor
Education
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Boston Children's Hospital -
National Capital Consortium -
University of Virginia School of Medicine
Hospital
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University of Virginia Medical Center -
University Hospitals Case Medical Center
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