Associate Professor of Medicine, Brigham and Women's Hospital
Pediatric Hematology & Oncology
Dr. Barry H. Paw, MD
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Barry H. Paw practices Pediatric Hematology & Oncology. He graduated from David Geffen School of Medicine at UCLA. David Geffen School of Medicine at UCLA is one of the top medical schools in the US. David Geffen School of Medicine at UCLA has a rank of 13 in research and a 7 in primary care He has 1 awards "Elected Member". Barry is also published. He has 82 publications published. The lastest publication: "Primary fibroblast cell culture.'
Publications
- Molecular cloning and functional characterization of zebrafish Slc4a3/Ae3 anion exchanger.
- Iron Regulatory Protein-1 Protects against Mitoferrin-1-deficient Porphyria.
- Macrocytic Anemia and Mitochondriopathy Resulting from a Defect in Sideroflexin 4.
- ATP-binding cassette B10 regulates early steps of heme synthesis.
- Snx3 Regulates Recycling of the Transferrin Receptor and Iron Assimilation.
- Glucose metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo.
- Teleost growth factor independence (gfi) genes differentially regulate successive waves of hematopoiesis.
- Mitochondrial Atpif1 regulates haem synthesis in developing erythroblasts.
- Mutation mapping and identification by whole-genome sequencing.
- Heme metabolism and erythropoiesis.
- ABCB6 Mutations Cause Ocular Coloboma.
- Abnormal mitoferrin-1 expression in patients with erythropoietic protoporphyria.
- Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis.
- Targeted deletion of the mouse Mitoferrin1 gene: from anemia to protoporphyria.
- Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2.
- Iron and porphyrin trafficking in heme biogenesis.
- miR-451 protects against erythroid oxidant stress by repressing 14-3-3zeta.
- Ferrochelatase forms an oligomeric complex with mitoferrin-1 and Abcb10 for erythroid heme biosynthesis.
- The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish.
- Abcb10 physically interacts with mitoferrin-1 (Slc25a37) to enhance its stability and function in the erythroid mitochondria.
- Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis.
- Mutations affecting the secretory COPII coat component SEC23B cause congenital dyserythropoietic anemia type II.
- Zebrafish kidney stromal cell lines support multilineage hematopoiesis.
- Construction and application of a zebrafish array comparative genomic hybridization platform.
- Regulation of mitochondrial iron import through differential turnover of mitoferrin 1 and mitoferrin 2.
- Carboxypeptidase A5 identifies a novel mast cell lineage in the zebrafish providing new insight into mast cell fate determination.
- Zebrafish mutants with disrupted early T-cell and thymus development identified in early pressure screen.
- Identification of ZBP-89 as a novel GATA-1-associated transcription factor involved in megakaryocytic and erythroid development.
- A GATA-1-regulated microRNA locus essential for erythropoiesis.
- Zebrafish ae2.2 encodes a second slc4a2 anion exchanger.
- Network of coregulated spliceosome components revealed by zebrafish mutant in recycling factor p110.
- Vascular endothelial growth factor receptor signaling is required for cardiac valve formation in zebrafish.
- Analysis of thrombocyte development in CD41-GFP transgenic zebrafish.
- Zebrafish slc4a2/ae2 anion exchanger: cDNA cloning, mapping, functional characterization, and localization.
- The pu.1 promoter drives myeloid gene expression in zebrafish.
- Zebrafish as a model of human hematologic disorders.
- Cloning and characterization of an Mx gene and its corresponding promoter from the zebrafish, Danio rerio.
- Transplantation and in vivo imaging of multilineage engraftment in zebrafish bloodless mutants.
- The zebrafish spi1 promoter drives myeloid-specific expression in stable transgenic fish.
- Zebrafish: a genetic model for vertebrate organogenesis and human disorders.
- Cell-specific mitotic defect and dyserythropoiesis associated with erythroid band 3 deficiency.
- Characterization of embryonic globin genes of the zebrafish.
- The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1).
- Zebrafish SPI-1 (PU.1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning.
- Characterization of zebrafish merlot/chablis as non-mammalian vertebrate models for severe congenital anemia due to protein 4.1 deficiency.
- Antagonistic roles of the ERK and p38 MAPK signalling pathways in globin expression, haem biosynthesis and iron uptake.
- In vivo inactivation of MASTL kinase results in thrombocytopenia.
- Haem homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins.
- montalcino, A zebrafish model for variegate porphyria.
- Mitoferrin is essential for erythroid iron assimilation.
- Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis.
- Functional conservation of erythropoietin signaling in zebrafish.
- Cardiac hypertrophy involves both myocyte hypertrophy and hyperplasia in anemic zebrafish.
- Development and validation of a HPLC method for the determination of cetirizine in pharmaceutical dosage forms.
- Thin-layer chromatographic analysis of fludarabine and formycin A in human plasma.
- Vertebrate genome evolution and the zebrafish gene map.
- An orthologue of the kit-related gene fms is required for development of neural crest-derived xanthophores and a subpopulation of adult melanocytes in the zebrafish, D...
- Determination of zopiclone in tablets by HPLC and UV-spectrophotometry.
- Determination of fludarabine phosphate in human plasma using reversed phase high-performance liquid chromatography.
- Identification of flecainide and lorcainide in blood by means of TLC.
- Chromatographic analysis (TLC) of uracil arabinoside, cytosine arabinoside, uracil and cytosine in human plasma.
- The cloche and spadetail genes differentially affect hematopoiesis and vasculogenesis.
- Radiation hybrid mapping of the zebrafish genome.
- High-performance liquid chromatographic assay of formycin A in plasma after solid-phase extraction.
- Gene duplication of zebrafish JAK2 homologs is accompanied by divergent embryonic expression patterns: only jak2a is expressed during erythropoiesis.
- Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter.
- Zebrafish: a genetic approach in studying hematopoiesis.
- Characterization of whole genome radiation hybrid mapping resources for non-mammalian vertebrates.
- Positional cloning of the zebrafish sauternes gene: a model for congenital sideroblastic anaemia.
- Primary fibroblast cell culture.
- Zebrafish stat3 is expressed in restricted tissues during embryogenesis and stat1 rescues cytokine signaling in a STAT1-deficient human cell line.
- SCL/Tal-1 transcription factor acts downstream of cloche to specify hematopoietic and vascular progenitors in zebrafish.
- A third mutation at the CpG dinucleotide of codon 504 and a silent mutation at codon 506 of the HEX A gene.
- Juvenile GM2 gangliosidosis caused by substitution of histidine for arginine at position 499 or 504 of the alpha-subunit of beta-hexosaminidase.
- Frequency of three Hex A mutant alleles among Jewish and non-Jewish carriers identified in a Tay-Sachs screening program.
- Normal transcription of the beta-hexosaminidase alpha-chain gene in the Ashkenazi Tay-Sachs mutation.
- Molecular basis of adult-onset and chronic GM2 gangliosidoses in patients of Ashkenazi Jewish origin: substitution of serine for glycine at position 269 of the alpha-s...
- Hereditary spherocytosis in zebrafish riesling illustrates evolution of erythroid beta-spectrin structure, and function in red cell morphogenesis and membrane stability.
- Modification of bacterial artificial chromosomes through chi-stimulated homologous recombination and its application in zebrafish transgenesis.
- Cloning of the zebrafish retsina blood mutation: a genetic model for dyserythropoiesis and erythroid cytokinesis.
- Myelopoiesis in the zebrafish, Danio rerio.
Schools
University of California At Los Angeles
Harvard Med SchChldns Hospital
Chldns HospDana Farber Canc Institute
Conditions Treated
- Acute Leukemia
Doctors Specialties
- Pediatric Hematology
- Oncology
Accepted Insurances
Awards
- Elected Member
Education
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Boston Children's Hospital -
David Geffen School of Medicine at UCLA
Hospital
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Brigham and Women's Hospital -
Dana-Farber Cancer Institute
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