Physician
Internal Medicine
Dr. Anthony F. Valente, MD
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Anthony Valente works in the field of Internal Medicine. He researched medicine at Penn State College of Medicine. Anthony Valente is a published doctor as well. He has 98 publications published. The latest was: Ca2+ channel inhibition induced by nitric oxide in rat insulinoma RINm5F cells. He accepts Medicare payments and is registered with Medicare.gov.
Publications
- Pressure overload induces IL-18 and IL-18R expression, but markedly suppresses IL-18BP expression in a rabbit model. IL-18 potentiates TNF-α-induced cardiomyocyte death.
- OxLDL induces endothelial dysfunction and death via TRAF3IP2. Inhibition by HDL3 and AMPK activators.
- Docosahexaenoic acid reverses angiotensin II-induced RECK suppression and cardiac fibroblast migration.
- Angiotensin II stimulates cardiac fibroblast migration via the differential regulation of matrixins and RECK.
- Acetylsalicylic Acid Inhibits IL-18-Induced Cardiac Fibroblast Migration through the Induction of RECK.
- TRAF3IP2 mediates interleukin-18-induced cardiac fibroblast migration and differentiation.
- Interleukin-18 enhances IL-18R/Nox1 binding, and mediates TRAF3IP2-dependent smooth muscle cell migration. Inhibition by simvastatin.
- Advanced oxidation protein products induce cardiomyocyte death via Nox2/Rac1/superoxide-dependent TRAF3IP2/JNK signaling.
- CIKS (Act1 or TRAF3IP2) mediates high glucose-induced endothelial dysfunction.
- Lymphoscintigraphic evaluation in patients after erysipelas.
- Interaction between the water soluble poly{1,4-phenylene-[9,9-bis(4-phenoxy butylsulfonate)]fluorene-2,7-diyl} copolymer and ionic surfactants followed by spectroscopi...
- Identification of monocyte chemotactic activity produced by malignant cells.
- Monocyte chemotactic proteins from human tumor cells.
- Regulated expression of MCP-1 by osteoblastic cells in vitro and in vivo.
- Ca2+ channel inhibition induced by nitric oxide in rat insulinoma RINm5F cells.
- Prevention of atherosclerosis and end-organ damage: a basis for antihypertensive interventional strategies.
- Evolution of foam cells in subcutaneous rabbit carrageenan granulomas. II. Tissue and macrophage lipid composition.
- Atherosclerosis as an inflammatory process. The roles of the monocyte-macrophage.
- Monocyte-macrophage participation in atherogenesis: inflammatory components of pathogenesis.
- Initial characterization of the carbohydrate structure of MCP-1.
- Expression of monocyte chemoattractant protein 1 in human osteoblastic cells stimulated by proinflammatory mediators.
- Expression of monocyte chemoattractant protein 1 mRNA in human idiopathic pulmonary fibrosis.
- Elevated expression of monocyte chemoattractant protein 1 by vascular smooth muscle cells in hypercholesterolemic primates.
- The expression of monocyte chemoattractant protein-1 and other chemokines by osteoblasts.
- Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein...
- Purification of a monocyte chemotactic factor secreted by nonhuman primate vascular cells in culture.
- Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells.
- The expression of monocyte chemotactic protein (MCP-1) in human vascular endothelium in vitro and in vivo.
- Aortic intimal monocyte recruitment in the normo and hypercholesterolemic baboon (Papio cynocephalus). An ultrastructural study: implications in atherogenesis.
- Macrophage LXRα gene therapy ameliorates atherosclerosis as well as hypertriglyceridemia in LDLR(-/-) mice.
- Initial characterization of a peripheral blood mononuclear cell chemoattractant derived from cultured arterial smooth muscle cells.
- Evolution of foam cells in subcutaneous rabbit carrageenan granulomas: I. Light-microscopic and ultrastructural study.
- Low-density lipoprotein endocytosis. II. Influence of the multivalent ligand cationized ferritin on acetylated low-density lipoprotein endocytosis in cultured cells.
- Thrombosis and the development of atherosclerosis: Rokitansky revisited.
- A modern view of atherogenesis.
- Atherosclerosis. Potential targets for stabilization and regression.
- Pathogenesis of the atherosclerotic lesion. Implications for diabetes mellitus.
- Pathophysiology of the atherogenic process.
- Cellular mechanisms in the response of the arterial wall to injury and repair.
- The pathogenesis of atherosclerosis: an overview.
- Post-translational modification of a monocyte-specific chemoattractant synthesized by glioma, osteosarcoma, and vascular smooth muscle cells.
- Human monocyte colony-stimulating factor stimulates the gene expression of monocyte chemotactic protein-1 and increases the adhesion of monocytes to endothelial monola...
- Monocyte chemoattractant protein-1 mediates monocyte/macrophage influx in anti-thymocyte antibody-induced glomerulonephritis.
- Characterization of monocyte chemotactic protein-1 binding to human monocytes.
- Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells.
- Stimulation of albumin endocytosis by cationized ferritin in cultured aortic smooth muscle cells.
- Flow-mediated modulation of selected biologic and molecular determinants related to vascular endothelial activation.
- Evolution of human and non-human primate CC chemokine receptor 5 gene and mRNA. Potential roles for haplotype and mRNA diversity, differential haplotype-specific trans...
- Mechanisms in intimal monocyte-macrophage recruitment. A special role for monocyte chemotactic protein-1.
- A novel biologic activity of thrombin: stimulation of monocyte chemotactic protein production.
- Thrombin stimulates proliferation of liver fat-storing cells and expression of monocyte chemotactic protein-1: potential role in liver injury.
- A complex element regulates IFN-gamma-stimulated monocyte chemoattractant protein-1 gene transcription.
- Thrombin regulates expression of monocyte chemoattractant protein-1 in vascular smooth muscle cells.
- Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines.
- Regulation of low shear flow-induced HAEC VCAM-1 expression and monocyte adhesion.
- Transcriptional regulation of the p67phox gene: role of AP-1 in concert with myeloid-specific transcription factors.
- Gamma interferon stimulates monocyte chemotactic protein (MCP-1) in human mesangial cells.
- PU.1 is essential for p47(phox) promoter activity in myeloid cells.
- Cultured primate aortic smooth muscle cells express both the PDGF-A and PDGF-B genes but do not secrete mitogenic activity or dimeric platelet-derived growth factor pr...
- Critical flanking sequences of PU.1 binding sites in myeloid-specific promoters.
- Interleukin-17A stimulates cardiac fibroblast proliferation and migration via negative regulation of the dual-specificity phosphatase MKP-1/DUSP-1.
- β2 adrenergic activation induces the expression of IL-18 binding protein, a potent inhibitor of isoproterenol induced cardiomyocyte hypertrophy in vitro and myocardial...
- Angiotensin-II type 1 receptor and NOX2 mediate TCF/LEF and CREB dependent WISP1 induction and cardiomyocyte hypertrophy.
- Interleukin-18/WNT1-inducible signaling pathway protein-1 signaling mediates human saphenous vein smooth muscle cell proliferation.
- Novel regulation of parkin function through c-Abl-mediated tyrosine phosphorylation: implications for Parkinson's disease.
- Interleukin-18 induces EMMPRIN expression in primary cardiomyocytes via JNK/Sp1 signaling and MMP-9 in part via EMMPRIN and through AP-1 and NF-kappaB activation.
- EMMPRIN activates multiple transcription factors in cardiomyocytes, and induces interleukin-18 expression via Rac1-dependent PI3K/Akt/IKK/NF-kappaB andMKK7/JNK/AP-1 si...
- WNT1-inducible signaling pathway protein-1 activates diverse cell survival pathways and blocks doxorubicin-induced cardiomyocyte death.
- Regulation of phagocyte NADPH oxidase by hydrogen peroxide through a Ca(2+)/c-Abl signaling pathway.
- Resveratrol blocks interleukin-18-EMMPRIN cross-regulation and smooth muscle cell migration.
- WISP1, a pro-mitogenic, pro-survival factor, mediates tumor necrosis factor-alpha (TNF-alpha)-stimulated cardiac fibroblast proliferation but inhibits TNF-alpha-induce...
- Neutralization of interleukin-18 ameliorates ischemia/reperfusion-induced myocardial injury.
- Adiponectin blocks interleukin-18-mediated endothelial cell death via APPL1-dependent AMP-activated protein kinase (AMPK) activation and IKK/NF-kappaB/PTEN suppression.
- Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts.
- Carbon monoxide donors or heme oxygenase-1 (HO-1) overexpression blocks interleukin-18-mediated NF-kappaB-PTEN-dependent human cardiac endothelial cell death.
- Novel redox-dependent regulation of NOX5 by the tyrosine kinase c-Abl.
- Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation.
- Interleukin-18 stimulates fibronectin expression in primary human cardiac fibroblasts via PI3K-Akt-dependent NF-kappaB activation.
- Regulation of NOX1 expression by GATA, HNF-1alpha, and Cdx transcription factors.
- IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation.
- Interleukin-17 stimulates C-reactive protein expression in hepatocytes and smooth muscle cells via p38 MAPK and ERK1/2-dependent NF-kappaB and C/EBPbeta activation.
- A preliminary study of the baboon prostate pathophysiology.
- NOX1 NADPH oxidase regulation by the NOXA1 SH3 domain.
- Development of a synthetic promoter for macrophage gene therapy.
- TLR4-NOX4-AP-1 signaling mediates lipopolysaccharide-induced CXCR6 expression in human aortic smooth muscle cells.
- Interleukin-18-induced human coronary artery smooth muscle cell migration is dependent on NF-kappaB- and AP-1-mediated matrix metalloproteinase-9 expression and is inh...
- Interleukin-18 induces human cardiac endothelial cell death via a novel signaling pathway involving NF-kappaB-dependent PTEN activation.
- PI 3 kinase-dependent Akt kinase and PKCepsilon independently regulate interferon-gamma-induced STAT1alpha serine phosphorylation to induce monocyte chemotactic protei...
- The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necr...
- A variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer.
- Nuclear factor kappa B activation by NADPH oxidases.
- Mechanisms of activation of NADPH oxidases.
- Regulation of the estrogen receptor alpha minimal promoter by Sp1, USF-1 and ERalpha.
- Alternative spliced variants of the alpha-methylacyl-CoA racemase gene and their expression in prostate cancer.
- IkappaBalpha-dependent regulation of low-shear flow-induced NF-kappa B activity: role of nitric oxide.
- Regulation of calreticulin expression during induction of differentiation in human myeloid cells. Evidence for remodeling of the endoplasmic reticulum.
- Multiple PU.1 sites cooperate in the regulation of p40(phox) transcription during granulocytic differentiation of myeloid cells.
Schools
Pennsylvania State University College of Medicine
Mercy Hospital
Doctors Specialties
- Internal Medicine
Accepted Insurances
Education
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Penn State College of Medicine
Drug Facts
| NPI NUMBER | 1538197835 | |
| NPPES Provider LastName | VALENTE | |
| NPPES Provider FirstName | ANTHONY | |
| NPPES Provider ZIPCode | 182015852 | |
| NPPES Provider State | PA | |
| Specialty Description | Internal Medicine | |
| Total Claim Count | 176.0 | |
| Distinct Opioid Count | 0.0 | |
| Opioid Claim Count | 0.0 | |
| Percent Opioid Claims | 0.0 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1538197835 |
| Last Name Of The Provider | VALENTE |
| First Name Of The Provider | ANTHONY |
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