Assistant Professor of Otolaryngology - Head and Neck Surgery / Director of the Translational Head and Neck Cancer Research Program
Otolaryngology (ENT)
Dr. Anthony C. Nichols, MD
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Anthony Nichols is an expert in the field of Otolaryngology (ENT). He received 6 awards: "Surgical Oncology Award of Academic Excellence: for excellence in research and education.", "Surgical Oncology Award of Excellence - for excellence in research, teaching andleadership", "Best poster - Oncolytic poxviruses demonstrate potent control of anaplastic thyroidcancer.", "Best Paper - Detection of circulating tumor cells in head and neck cancer", "Alpha Omega Alpha Member" and "Scholarship". Anthony Nichols is a published physician as well. He has 42 publications published. The latest was: Genomically driven precision medicine to improve outcomes in anaplastic thyroid cancer.
Publications
- Hotspot activating PRKD1 somatic mutations in polymorphous low-grade adenocarcinomas of the salivary glands.
- Genomically driven precision medicine to improve outcomes in anaplastic thyroid cancer.
- Temporal changes in the efficacy of chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck: A systematic review and meta-analysis.
- CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.
- The control of anaplastic thyroid carcinoma cell lines by oncolytic poxviruses.
- Variable expression of the forgotten oncogene E5 in HPV-positive oropharyngeal cancer.
- Viral retasking of hBre1/RNF20 to recruit hPaf1 for transcriptional activation.
- Defining the genomic landscape of head and neck cancers through next-generation sequencing.
- The human papillomavirus E7 proteins associate with and alter p190RhoGAP function.
- Human papillomavirus in head and neck cancer.
- Transoral robotic total laryngectomy: Report of 3 cases.
- Can radiological changes in lymph node volume during treatment predict success of radiation therapy in patients with locally advanced head and neck squamous cell carci...
- Vaccinia Virus Outperforms a Panel of Other Poxviruses as a Potent Oncolytic Agent for the Control of Head and Neck Squamous Cell Carcinoma Cell Lines.
- The epidemic of human papillomavirus and oropharyngeal cancer in a Canadian population.
- High frequency of activating PIK3CA mutations in human papillomavirus-positive oropharyngeal cancer.
- A new angle to mandibular reconstruction: the scapular tip free flap.
- Development of a transoral robotic surgery program in Canada.
- Does HPV type affect outcome in oropharyngeal cancer?
- Comparison of fibular and scapular osseous free flaps for oromandibular reconstruction: a patient-centered approach to flap selection.
- A case report and genetic characterization of a massive acinic cell carcinoma of the parotid with delayed distant metastases.
- The use of autologous platelet and plasma products in salvage neck dissections: a prospective clinical study evaluating early and late wound healing.
- Early-stage squamous cell carcinoma of the oropharynx: radiotherapy vs. trans-oral robotic surgery (ORATOR)--study protocol for a randomized phase II trial.
- A Pilot Study Comparing HPV-Positive and HPV-Negative Head and Neck Squamous Cell Carcinomas by Whole Exome Sequencing.
- Frequent mutations in TP53 and CDKN2A found by next-generation sequencing of head and neck cancer cell lines.
- Postlaryngectomy pharyngocutaneous fistula: determining the risk of preoperative tracheostomy and primary tracheoesophageal puncture.
- The role of transoral robotic surgery in the management of oropharyngeal cancer: a review of the literature.
- Ki-67 expression predicts radiotherapy failure in early glottic cancer.
- A descriptive analysis of the relationship between quality of life and distress in individuals with head and neck cancer.
- Detection of circulating tumor cells in advanced head and neck cancer using the cellsearch system.
- The buccinator flap: a review of current clinical applications.
- Comparison of endoscopic laser resection versus radiation therapy for the treatment of early glottic carcinoma.
- Surgical salvage of the oropharynx after failure of organ-sparing therapy.
- Contact endoscopy as a novel technique in the detection and diagnosis of mucosal lesions in the head and neck: a brief review.
- Bcl2 and human papilloma virus 16 as predictors of outcome following concurrent chemoradiation for advanced oropharyngeal cancer.
- Bcl-2 blocks cisplatin-induced apoptosis and predicts poor outcome following chemoradiation treatment in advanced oropharyngeal squamous cell carcinoma.
- HPV-16 infection predicts treatment outcome in oropharyngeal squamous cell carcinoma.
- Esthesioneuroblastoma: the massachusetts eye and ear infirmary and massachusetts general hospital experience with craniofacial resection, proton beam radiation, and ch...
- Racial differences in stage and survival in head and neck squamous cell carcinoma.
- Bryostatin-1 enhances barrier function in T84 epithelia through PKC-dependent regulation of tight junction proteins.
- Bryostatin-1 attenuates TNF-induced epithelial barrier dysfunction: role of novel PKC isozymes.
- Protein kinase epsilon dampens the secretory response of model intestinal epithelia during ischemia.
Doctors Specialties
- Ear, Nose, and Throat
- Otolaryngology (ENT)
Accepted Insurances
Awards
- Surgical Oncology Award of Academic Excellence: for excellence in research and education.
- Surgical Oncology Award of Excellence - for excellence in research, teaching and leadership
- Best poster - Oncolytic poxviruses demonstrate potent control of anaplastic thyroid cancer.
- Best Paper - Detection of circulating tumor cells in head and neck cancer
- Alpha Omega Alpha Member
- Scholarship
Education
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Massachusetts Eye & Ear Infirmary -
Massachusetts General Hospital -
University of Toronto Faculty of Medicine
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