Professor, Medicine, University of Washington School of Medicine
Infectious Disease
Dr. Ann E. Stapleton, MD
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Stapleton practices Infectious Disease. She studied medicine at Albert Einstein College of Medicine of Yeshiva University. She over the years received 6 awards: "Fellow", "Masaaki Ohkoshi Award", "Edwin Beer Fellowship in Urology and Urology-Related Fields", "Alpha Omega Alpha", "Janet M. Glasgow Memorial Achievement Citation" and "Harvard National Scholar". Dr. Ann E. Stapleton is a published doctor as well. She has 70 publications published. The latest was: Effect of Staphylococcus aureus bacteria and bacterial toxins on meningeal permeability in vitro.
Publications
- Urinary Tract Infection Pathogenesis: Host Factors.
- Voided midstream urine culture and acute cystitis in premenopausal women.
- The Type 1 Pili Regulator Gene fimX and Pathogenicity Island PAI-X as Molecular Markers of Uropathogenic Escherichia coli.
- Escherichia coli isolates that carry vat, fyuA, chuA, and yfcV efficiently colonize the urinary tract.
- Cranberry-containing products are associated with a protective effect against urinary tract infections.
- The siderophore yersiniabactin binds copper to protect pathogens during infection.
- Cefpodoxime vs ciprofloxacin for short-course treatment of acute uncomplicated cystitis: a randomized trial.
- Recurrent urinary tract infection and urinary Escherichia coli in women ingesting cranberry juice daily: a randomized controlled trial.
- Fimbrial Profiles Predict Virulence of Uropathogenic E. coli Strains: Contribution of Ygi and Yad Fimbriae.
- Randomized, Placebo-Controlled Phase 2 Trial of a Lactobacillus crispatus Probiotic Given Intravaginally for Prevention of Recurrent Urinary Tract Infection.
- Presence of Putative Repeat-in-Toxin Gene tosA in Escherichia coli Predicts Successful Colonization of the Urinary Tract.
- Family history and risk of recurrent cystitis and pyelonephritis in women.
- Prospective cohort study of microbial and inflammatory events immediately preceding Escherichia coli recurrent urinary tract infection in women.
- Urinary tract infections in women with type 1 diabetes mellitus: survey of female participants in the epidemiology of diabetes interventions and complications study co...
- Genetic variation of the human urinary tract innate immune response and asymptomatic bacteriuria in women.
- Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.
- Escherichia coli DraE adhesin-associated bacterial internalization by epithelial cells is promoted independently by decay-accelerating factor and carcinoembryonic anti...
- Phase I trial of a Lactobacillus crispatus vaginal suppository for prevention of recurrent urinary tract infection in women.
- Cranberry products inhibit adherence of p-fimbriated Escherichia coli to primary cultured bladder and vaginal epithelial cells.
- A novel TLR4-mediated signaling pathway leading to IL-6 responses in human bladder epithelial cells.
- Adherence of Lactobacillus crispatus to vaginal epithelial cells from women with or without a history of recurrent urinary tract infection.
- Urinary tract infection in women: new pathogenic considerations.
- Clonal analysis reveals high rate of structural mutations in fimbrial adhesins of extraintestinal pathogenic Escherichia coli.
- Novel mechanism of P-fimbriated Escherichia coli virulence in pyelonephritis.
- Amoxicillin-clavulanate vs ciprofloxacin for the treatment of uncomplicated cystitis in women: a randomized trial.
- Risk factors associated with acute pyelonephritis in healthy women.
- Urologic complications of diabetes.
- A new candidate vaccine for Escherichia coli pyelonephritis.
- Variation in frequency of the virulence-factor gene in Escherichia coli clones colonizing the stools and urinary tracts of healthy prepubertal girls.
- Novel approaches to prevention of urinary tract infections.
- Urinary tract infections in patients with diabetes.
- Analysis of urinary Escherichia coli isolates for ability to produce Shiga toxin.
- Precise and rapid assessment of Escherichia coli adherence to vaginal epithelial cells by flow cytometry.
- ABO and P1 blood group antigen expression and stx genotype and outcome of childhood Escherichia coli O157:H7 infections.
- Clonal relationships and extended virulence genotypes among Escherichia coli isolates from women with a first or recurrent episode of cystitis.
- Effects of vaginal intercourse with and without a condom on vaginal flora and vaginal epithelium.
- A prospective study of asymptomatic bacteriuria in sexually active young women.
- Epithelial cell layer thickness and immune cell populations in the normal human vagina at different stages of the menstrual cycle.
- Risk factors for recurrent urinary tract infection in young women.
- Effects of oral contraceptive pill use on vaginal flora and vaginal epithelium.
- Influence of the normal menstrual cycle on vaginal tissue, discharge, and microflora.
- Expression of virulence factors among Escherichia coli isolated from the periurethra and urine of children with neurogenic bladder on intermittent catheterization.
- Perineal anatomy and urine-voiding characteristics of young women with and without recurrent urinary tract infections.
- Prevention of recurrent urinary-tract infections in women.
- Effect of Staphylococcus aureus bacteria and bacterial toxins on meningeal permeability in vitro.
- Host factors in susceptibility to urinary tract infections.
- The P histo-blood group-related glycosphingolipid sialosyl galactosyl globoside as a preferred binding receptor for uropathogenic Escherichia coli: isolation and struc...
- Inverse association of H2O2-producing lactobacilli and vaginal Escherichia coli colonization in women with recurrent urinary tract infections.
- The globoseries glycosphingolipid sialosyl galactosyl globoside is found in urinary tract tissues and is a preferred binding receptor In vitro for uropathogenic Escher...
- Comparison of Escherichia coli strains recovered from human cystitis and pyelonephritis infections in transurethrally challenged mice.
- Cytotoxicity of hemolytic, cytotoxic necrotizing factor 1-positive and -negative Escherichia coli to human T24 bladder cells.
- papG alleles of Escherichia coli strains causing first-episode or recurrent acute cystitis in adult women.
- Prevention of urinary tract infection.
- Urovirulence determinants in Escherichia coli strains causing prostatitis.
- Antecedent antimicrobial use increases the risk of uncomplicated cystitis in young women.
- Characteristics and prevalence within serogroup O4 of a J96-like clonal group of uropathogenic Escherichia coli O4:H5 containing the class I and class III alleles of p...
- Hemolytic-uremic syndrome in a six-year-old girl after a urinary tract infection with Shiga-toxin-producing Escherichia coli O103:H2.
- A prospective study of risk factors for symptomatic urinary tract infection in young women.
- Comparison of expression of virulence factors by Escherichia coli causing cystitis and E. coli colonizing the periurethra of healthy girls.
- Chromosomal restriction fragment length polymorphism analysis of Escherichia coli strains causing recurrent urinary tract infections in young women.
- Hemagglutination, adherence, and surface properties of vaginal Lactobacillus species.
- Effect of secretor status on vaginal and rectal colonization with fimbriated Escherichia coli in women with and without recurrent urinary tract infection.
- Binding of uropathogenic Escherichia coli R45 to glycolipids extracted from vaginal epithelial cells is dependent on histo-blood group secretor status.
- Lack of circumcision increases the risk of urinary tract infection in young men.
- Urovirulence determinants in Escherichia coli isolates causing first-episode and recurrent cystitis in women.
- Postcoital antimicrobial prophylaxis for recurrent urinary tract infection. A randomized, double-blind, placebo-controlled trial.
- Urinary tract infections: from pathogenesis to treatment.
- What molecular steps determine the time course of the memory for short-term sensitization in Aplysia?
- TLR4-mediated expulsion of bacteria from infected bladder epithelial cells.
Schools
Albert Einstein College of Medicine of Yeshiva University
University Calif
University of Washington
Doctors Specialties
- Infectious Disease Medicine
- Infectious Disease
Accepted Insurances
Awards
- Fellow
- Masaaki Ohkoshi Award
- Edwin Beer Fellowship in Urology and Urology-Related Fields
- Alpha Omega Alpha
- Janet M. Glasgow Memorial Achievement Citation
- Harvard National Scholar
Education
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University of Washington -
UCSF -
Albert Einstein College of Medicine of Yeshiva University -
Harvard University
Hospital
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University of Washington Medical Center -
UW Medicine/Harborview Medical Center
Drug Facts
| NPI NUMBER | 1851477582 | |
| NPPES Provider LastName | STAPLETON | |
| NPPES Provider FirstName | ANN | |
| NPPES Provider ZIPCode | 981054760 | |
| NPPES Provider State | WA | |
| Specialty Description | Infectious Disease | |
| Total Claim Count | 160.0 | |
| Distinct Opioid Count | 1.0 | |
| Opioid Claim Count | 13.0 | |
| Percent Opioid Claims | 8.13 |
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1851477582 |
| Last Name Of The Provider | STAPLETON |
| First Name Of The Provider | ANN |
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