Eunice Kennedy Shriver National Institute of Child Health and Human Development

Internal Medicine

Dr. Anil B. Mukherjee practices Internal Medicine. Anil B. Mukherjee, MD is a published doctor as well. He has 32 publications published. The latest was: Mice homozygous for c.451C>T mutation in Cln1 gene recapitulate INCL phenotype.

Publications

---

• Mice homozygous for c.451C>T mutation in Cln1 gene recapitulate INCL phenotype.
• Oral cysteamine bitartrate and N-acetylcysteine for patients with infantile neuronal ceroid lipofuscinosis: a pilot study.
• Neuroprotection and lifespan extension in Ppt1(-/-) mice by NtBuHA: therapeutic implications for INCL.
• Stop codon read-through with PTC124 induces palmitoyl-protein thioesterase-1 activity, reduces thioester load and suppresses apoptosis in cultured cells from INCL pati...
• Genes, Environment and Allergic Asthma.
• Lack of an endogenous anti-inflammatory protein in mice enhances colonization of B16F10 melanoma cells in the lungs.
• Subdural fluid collections in patients with infantile neuronal ceroid lipofuscinosis.
• Children with infantile neuronal ceroid lipofuscinosis have an increased risk of hypothermia and bradycardia during anesthesia.
• Palmitoyl protein thioesterase-1 deficiency impairs synaptic vesicle recycling at nerve terminals, contributing to neuropathology in humans and mice.
• Uteroglobin: a steroid-inducible immunomodulatory protein that founded the Secretoglobin superfamily.
• Yin-yang: balancing act of prostaglandins with opposing functions to regulate inflammation.
• Uteroglobin inhibits prostaglandin F2alpha receptor-mediated expression of genes critical for the production of pro-inflammatory lipid mediators.
• Uteroglobin suppresses SCCA gene expression associated with allergic asthma.
• Increased susceptibility of mice lacking Clara cell 10-kDa protein to lung tumorigenesis by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a potent carcinogen in ciga...
• Uteroglobin represses allergen-induced inflammatory response by blocking PGD2 receptor-mediated functions.
• IFN-gamma stimulates the expression of a novel secretoglobin that regulates chemotactic cell migration and invasion.
• Lys 43 and Asp 46 in alpha-helix 3 of uteroglobin are essential for its phospholipase A2 inhibitory activity.
• RAGE signaling contributes to neuroinflammation in infantile neuronal ceroid lipofuscinosis.
• Induction of cyclooxygenase-2 by staurosporine through the activation of nuclear factor for IL-6 (NF-IL6) and activator protein 2 (AP2) in an osteoblast-like cell line.
• Omega-3 and omega-6 fatty acids suppress ER- and oxidative stress in cultured neurons and neuronal progenitor cells from mice lacking PPT1.
• Disruption of adaptive energy metabolism and elevated ribosomal p-S6K1 levels contribute to INCL pathogenesis: partial rescue by resveratrol.
• ER and oxidative stresses are common mediators of apoptosis in both neurodegenerative and non-neurodegenerative lysosomal storage disorders and are alleviated by chemi...
• Uteroglobin interacts with the heparin-binding site of fibronectin and prevents fibronectin-IgA complex formation found in IgA-nephropathy.
• Neutral ceramidase gene: role in regulating ceramide-induced apoptosis.
• Palmitoyl-protein thioesterase-1 deficiency mediates the activation of the unfolded protein response and neuronal apoptosis in INCL.
• Interaction of uteroglobin with lipocalin-1 receptor suppresses cancer cell motility and invasion.
• Palmitoyl-protein thioesterase-1 deficiency leads to the activation of caspase-9 and contributes to rapid neurodegeneration in INCL.
• Endoplasmic reticulum stress-induced caspase-4 activation mediates apoptosis and neurodegeneration in INCL.
• Mice lacking uteroglobin are highly susceptible to developing pulmonary fibrosis.
• Uteroglobin suppresses allergen-induced TH2 differentiation by down-regulating the expression of serum amyloid A and SOCS-3 genes.
• Production of lysophosphatidylcholine by cPLA2 in the brain of mice lacking PPT1 is a signal for phagocyte infiltration.

Schools

---

• State University of New York At Buffalo

Doctors Specialties

---

• Emergency Medicine
• Internal Medicine

Accepted Insurances

---

Helpful Reviews

---

Give Anonymous Review

Similar Doctors

---

	Dr. Frederick S. Thaler, MD This Doctor is OpenDoctor Recommended.
	Dr. Kristie A. Robson, MD
	Dr. Robert Rothstein, MD This Doctor is OpenDoctor Recommended.
	Dr. Matthew M. Leonard, MD This Doctor is OpenDoctor Recommended.
	Barbara Martinez This Doctor is OpenDoctor Recommended.
	Dr. Matthew S. Wright, MD This Doctor is OpenDoctor Recommended.
	Dr. Charles J. Calais, DO
	Dr. Omolara R. Adewuni, MD
	Dr. Ashish K. Jain, MD This Doctor is OpenDoctor Recommended.
	Dr. Derek C. Forsthoefel, MD
	Dr. Richard J. Havlik, MD
	Dr. Frederick W. Randolph, MD
	Dr. Leigh B. Lurie, MD This Doctor is OpenDoctor Recommended.

---

Doctor Directory | TOS | twitter | FB | Angel | blog