Adjunct Associate Professor, Cardiology, Baylor College of Medicine
Cardiology
Dr. Ali J. Marian, MD
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Doctor Ali J. Marian, MD works in the field of Cardiology. He graduated from Baylor College of Medicine. Marian is a published MD. He has 99 papers published. The most current publication "In vivo short-term expression of a hypertrophic cardiomyopathy mutation in adult rabbit myocardium: myofibrillar incorporation without early disarray."
Publications
- Clinical applications of molecular genetic discoveries.
- Recent developments in cardiovascular genetics and genomics.
- Release kinetics of circulating cardiac myosin binding protein-C following cardiac injury.
- Causality in genetics: the gradient of genetic effects and back to Koch postulates of causality.
- The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic Cardiomyopathy.
- On the diagnostic utility of junction plakoglobin in arrhythmogenic right ventricular Cardiomyopathy.
- The Discovery of the ACE2 Gene.
- Errors in DNA replication and genetic Diseases.
- Pathogenesis of hypertrophic Cardiomyopathy caused by myozenin 2 mutations is independent of calcineurin activity.
- Challenges in Medical Applications of Whole Exome/Genome Sequencing Discoveries.
- Human Molecular Genetic and Functional Studies Identify TRIM63, Encoding Muscle RING Finger Protein 1, as a Novel Gene for Human Hypertrophic Cardiomyopathy.
- Elements of 'missing heritability'.
- The Enigma of Genetics Etiology of Atherosclerosis in the Post-GWAS Era.
- Molecular genetic studies of complex phenotypes.
- Modeling Human Disease Phenotype in Model Organisms: "It's Only a Model!".
- Molecular Genetic and Functional Characterization Implicate Muscle-Restricted Coiled-Coil Gene (MURC) as a Causal Gene for Familial Dilated Cardiomyopathy.
- Genome-wide association studies complemented with mechanistic biological studies identify sortilin 1 as a novel regulator of cholesterol trafficking.
- Determinants of plasma vitamin D levels in patients with acute Coronary syndromes.
- Medical DNA sequencing.
- PCSK9 as a therapeutic target in atherosclerosis.
- Editorial review: DNA sequence variants and the practice of medicine.
- Arrhythmogenic right ventricular Cardiomyopathy is a disease of cardiac stem cells.
- Update on hypertrophic Cardiomyopathy.
- Nature's genetic gradients and the clinical phenotype.
- Experimental therapies in hypertrophic Cardiomyopathy.
- Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular Cardiomyopathy.
- Mutations in smooth muscle alpha-actin (ACTA2) cause Coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease.
- Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human Cardiomyopathy through thiol-se...
- Contemporary treatment of hypertrophic Cardiomyopathy.
- Clinical implications of the "personal" genome.
- Genome-wide association study of susceptibility alleles for Coronary artery disease.
- Genetic determinants of cardiac hypertrophy.
- Surprises of the genome and "personalized" medicine.
- Enhanced transmural fiber rotation and connexin 43 heterogeneity are associated with an increased upper limit of vulnerability in a transgenic rabbit model of human hy...
- Clinical significance of single nucleotide polymorphisms in PCSK9.
- A novel genetic risk factor for myocardial infarction.
- Phenotypic plasticity of sarcomeric protein mutations.
- Myozenin 2 is a novel gene for human hypertrophic Cardiomyopathy.
- Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular Cardiomyopathy.
- Interleukin-18 and cardiovascular events.
- Matrix metalloproteinase-I gene variants and risk of myocardial infarction.
- Antifibrotic effects of antioxidant N-acetylcysteine in a mouse model of human hypertrophic Cardiomyopathy mutation.
- Regulatable atrial natriuretic peptide gene therapy for Hypertension.
- A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels...
- Pharmacogenetic study of statin therapy and cholesterol reduction.
- Cholesteryl ester transfer protein TaqIB polymorphism in the cholesterol and recurrent events study.
- Can an energy-deficient heart grow bigger and stronger?
- On predictors of sudden cardiac death in hypertrophic Cardiomyopathy.
- Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism.
- Sequencing Your Genome: What Does It Mean?
- Urinary virulence of Proteus mirabilis in two experimental mouse models.
- Plasma homocyst(e)ine concentration, but not MTHFR genotype, is associated with variation in carotid plaque area.
- Beta-adrenergic receptors signaling and heart failure in mice, rabbits and humans.
- Mitochondrial genetics and human systemic Hypertension.
- Commentaries--another addition to the portfolio of Circulation Research.
- Circulation Research and human genetic studies.
- Genetic markers: genes involved in human Hypertension.
- Genetic markers: genes involved in atherosclerosis.
- Biomarkers of cardiac Disease.
- Molecular approaches for screening of genetic Diseases.
- Strategic approaches to unraveling genetic causes of cardiovascular Diseases.
- Molecular mechanisms of cardiac myofilament activation: modulation by pH and a troponin T mutant R92Q.
- The personal genome and the practice of cardiovascular medicine.
- Human polymorphism of P-selectin glycoprotein ligand 1 attributable to variable numbers of tandem decameric repeats in the mucinlike region.
- On mice, rabbits, and human heart failure.
- Inadvertent administration of rtPA to a patient with type 1 aortic dissection and subsequent cardiac tamponade.
- Platelet glycoprotein IIIa PlA polymorphism and myocardial infarction.
- To screen or not is not the question--it is when and how to screen.
- An overview of nucleic acids and gene regulation.
- Molecular genetics of cardiomyopathies.
- On Koch''s postulates, causality and genetics of cardiomyopathies.
- On genetics, inflammation, and abdominal aortic aneurysm: can single nucleotide polymorphisms predict the outcome?
- On genetics of dilated Cardiomyopathy and transgenic models: all is not crystal clear in myopathic hearts.
- On genetic and phenotypic variability of hypertrophic Cardiomyopathy: nature versus nurture.
- Pathogenesis of diverse clinical and pathological phenotypes in hypertrophic Cardiomyopathy.
- Prognostic significance of beta-myosin heavy chain mutations is reflective of their hypertrophic expressivity in patients with hypertrophic Cardiomyopathy.
- Apolipoprotein epsilon 4 is not a genetic risk factor for Coronary artery disease or restenosis after percutaneous transluminal Coronary angioplasty.
- Sudden cardiac death in patients with hypertrophic Cardiomyopathy: from bench to bedside with an emphasis on genetic markers.
- "Into thin air" and the genetics of complex traits.
- Identifying modifier loci in existing genome scan data.
- In vivo short-term expression of a hypertrophic Cardiomyopathy mutation in adult rabbit myocardium: myofibrillar incorporation without early disarray.
- MYH11 mutations result in a distinct vascular pathology driven by insulin-like growth factor 1 and angiotensin II.
- Molecular genetics and pathogenesis of hypertrophic Cardiomyopathy.
- Molecular genetics and pathogenesis of arrhythmogenic right ventricular Cardiomyopathy: a disease of cardiac stem cells.
- Coordinated series of studies to evaluate characteristics and mechanisms of acute Coronary syndromes in high-risk patients randomly assigned to enoxaparin or unfractio...
- A missense mutation in the beta myosin heavy chain gene is a predictor of premature sudden death in patients with hypertrophic Cardiomyopathy.
- Nuclear Plakoglobin Is Essential for Differentiation of Cardiac Progenitor Cells to Adipocytes in Arrhythmogenic Right Ventricular Cardiomyopathy.
- Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of Coronary atherosclerosis.
- Association of angiotensin I-converting enzyme gene polymorphism with myocardial ischemia and patency of infarct-related Artery in patients with acute myocardial infar...
- Early diagnosis of acute myocardial infarction based on assay for subforms of creatine kinase-MB.
- Genetic risk factors for myocardial infarction.
- Modifier genes for hypertrophic Cardiomyopathy.
- A variant of human paraoxonase/arylesterase (HUMPONA) gene is a risk factor for Coronary artery disease.
- Angiotensin-I converting enzyme genotype DD is a risk factor for Coronary artery disease.
- A common mutation in methylenetetrahydrofolate reductase gene is not a major risk of Coronary artery disease or myocardial infarction.
- Molecular genetics of hypertrophic Cardiomyopathy.
- Decreased left ventricular ejection fraction in transgenic mice expressing mutant cardiac troponin T-Q(92), responsible for human hypertrophic Cardiomyopathy.
- Familial hypertrophic Cardiomyopathy: a paradigm of the cardiac hypertrophic response to injury.
Schools
Iran University of Medical Sciences Faculty of Medicine
Cook Co Hospital
Conditions Treated
- Cardiomyopathy
- Coronary Artery Disease (CAD)
- Hyperlipidemia
- Hypertension
- View All
Doctors Specialties
- Cardiology
Accepted Insurances
Education
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Baylor College of Medicine -
John H. Stroger Hospital of Cook County -
Tehran University of Medical Sciences School of Medicine
Hospital
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Baylor St. Luke's Medical Center
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