Associate Professor, Pathology, UC, Davis School of Medicine
Pathology
Dr. Alexander D. Borowsky, MD
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Dr. Alexander D. Borowsky works in the field of Pathology. He studied medicine at Vanderbilt University School of Medicine. Alexander Borowsky is a published doctor. He has 80 papers published. The most current publication "Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: a model for prostate cancer."
Publications
- CpG expedites regression of local and systemic tumors when combined with activatable nanodelivery.
- Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging.
- Mitochondrial MKP1 is a target for therapy-resistant HER2-positive breast cancer cells.
- Cellular heterogeneity profiling by hyaluronan probes reveals an invasive but slow-growing breast tumor subset.
- Mouse models of prostate cancer: picking the best model for the question.
- Androgen receptor splice variant AR3 promotes prostate cancer via modulating expression of autocrine/paracrine factors.
- Transgenic mammary epithelial osteopontin (spp1) expression induces proliferation and alveologenesis.
- Animal Models of Human Prostate Cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.
- Developmental and androgenic regulation of chromatin regulators EZH2 and ANCCA/ATAD2 in the prostate Via MLL histone methylase complex.
- Quantitation of fixative-induced morphologic and antigenic variation in mouse and human breast cancers.
- Magnetic Resonance Imaging Assessment of Effective Ablated Volume following High Intensity Focused Ultrasound.
- Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18.
- Metaplastic breast tumors with a dominant fibromatosis-like phenotype have a high risk of local recurrence.
- Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: a model for prostate cancer.
- Quantification of tumor vascularity and flow with amplitude color Doppler sonography in an experimental model: preliminary results.
- Meningitis caused by mixed anaerobic species complicating tethered cord syndrome.
- Hybrid peptide dendrimers for imaging of chemokine receptor 4 (CXCR4) expression.
- Choosing a mouse model: experimental biology in context--the utility and limitations of mouse models of breast cancer.
- Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type.
- S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart.
- Longitudinal investigation of permeability and distribution of macromolecules in mouse malignant transformation using PET.
- High-mannose glycans are elevated during breast cancer progression.
- Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity.
- ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control o...
- Assessment of carprofen and buprenorphine on recovery of mice after surgical removal of the mammary fat pad.
- Redefining the expression and function of the inhibitor of differentiation 1 in mammary gland development.
- Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.
- Pilot study on the effects of dietary conjugated linoleic acid on tumorigenesis and gene expression in PyMT transgenic mice.
- Siah2-dependent concerted activity of HIF and FoxA2 regulates formation of neuroendocrine phenotype and neuroendocrine prostate tumors.
- Deregulated E2F and the AAA+ coregulator ANCCA drive proto-oncogene ACTR/AIB1 overexpression in breast cancer.
- Precancer: sequentially acquired or predetermined?
- The membrane mucin MUC4 is elevated in breast tumor lymph node metastases relative to matched primary tumors and confers aggressive properties to breast cancer cells.
- Initial characterization of a dedicated breast PET/CT scanner during human imaging.
- Grade-dependent proteomics characterization of kidney cancer.
- Aberrant activation of androgen receptor in a new neuropeptide-autocrine model of androgen-insensitive prostate cancer.
- Use of bioluminescent imaging to assay the transplantation of immortalized human fetal hepatocytes into mice.
- Suppression of the negative regulator LRIG1 contributes to ErbB2 overexpression in breast cancer.
- Folate, DNA methylation, and mouse models of breast tumorigenesis.
- A cautionary note as to the use of pBi-L and related luciferase/transgenic vectors in the study of thyroid endocrinology.
- Mammary carcinoma behavior is programmed in the precancer stem cell.
- A human breast cell model of preinvasive to invasive transition.
- Special considerations in mouse models of breast cancer.
- Over 60% of NIH extramural funding involves animal-related research.
- EMT tumorigenesis in the mouse mammary gland.
- Disruption of the Flnb gene in mice phenocopies the human disease spondylocarpotarsal synostosis syndrome.
- From whence will they come? - A perspective on the acute shortage of pathologists in biomedical research.
- Disruption of Rxra gene in thymocytes and T lymphocytes modestly alters lymphocyte frequencies, proliferation, survival and T helper type 1/type 2 balance.
- p21 is a prognostic marker for renal cell carcinoma: implications for novel therapeutic approaches.
- Heterogeneity of mammary lesions represent molecular differences.
- Loss of Nrdp1 enhances ErbB2/ErbB3-dependent breast tumor cell growth.
- Preclinical imaging of mammary intraepithelial neoplasia with positron emission tomography.
- Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer.
- Histopathology as a predictive biomarker: strengths and limitations.
- Inflammation and atrophy precede prostatic neoplasia in a PhIP-induced rat model.
- Tyrosine kinase Etk/BMX is up-regulated in human prostate cancer and its overexpression induces prostate intraepithelial neoplasia in mouse.
- A serum glycomics approach to breast cancer biomarkers.
- Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ.
- Ablation of mouse phosphomannose isomerase (Mpi) causes mannose 6-phosphate accumulation, toxicity, and embryonic lethality.
- Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ.
- Therapy-induced malignant neoplasms in Nf1 mutant mice.
- Syngeneic mouse mammary carcinoma cell lines: two closely related cell lines with divergent metastatic behavior.
- A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis.
- MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer.
- Mice expressing SV40 T antigen directed by the intestinal trefoil factor promoter develop tumors resembling human small cell carcinoma of the colon.
- Molecular characterization of the transition to malignancy in a genetically engineered mouse-based model of ductal carcinoma in situ.
- Polyomavirus middle T-induced mammary intraepithelial neoplasia outgrowths: single origin, divergent evolution, and multiple outcomes.
- In vivo positron-emission tomography imaging of progression and transformation in a mouse model of mammary neoplasia.
- Mouse models of human cancers (part 3).
- Validation: the new challenge for pathology.
- Comparative pathology of nerve sheath tumors in mouse models and humans.
- Molecular analysis of metastasis in a polyomavirus middle T mouse model: the role of osteopontin.
- Mouse models of human cancers (Part 2).
- Chromosome instability and tumor predisposition inversely correlate with BLM protein levels.
- Cytosolic p21Waf1/Cip1 increases cell cycle transit in vascular smooth muscle cells.
- An antisense oligodeoxynucleotide to p21(Waf1/Cip1) causes apoptosis in human breast cancer cells.
- Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases.
- Mouse models of prostate cancer.
- Genetically engineering a mouse.
- A recombinant rhesus cytomegalovirus expressing enhanced green fluorescent protein retains the wild-type phenotype and pathogenicity in fetal macaques.
Schools
Vanderbilt University
Doctors Specialties
- Anatomic Pathology
- Pathology
Accepted Insurances
Education
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Vanderbilt University -
Vanderbilt University School of Medicine
Hospital
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University of California, Davis Medical Center
Helpful Reviews
Medicare Facts
| National Provider Identifier [NPI] | 1891777512 |
| Last Name Of The Provider | BOROWSKY |
| First Name Of The Provider | ALEXANDER |
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