Physician
Family Medicine
Caroline A. Kruse, ARNP
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Caroline A. Kruse, ARNP practices Family Medicine. He researched medicine at Stony Brook University School of Medicine. Caroline Kruse ARNP is also a published doctor. He has 51 paper published. The most recent paper is: Receptor expression, cytogenetic, and molecular analysis of six continuous human glioma cell lines.
Publications
- Implementing preclinical study findings to protocol design: translational studies with alloreactive CTL for gliomas.
- Cellular and vaccine therapeutic approaches for gliomas.
- Immunotherapy of malignant gliomas using autologous and allogeneic tissue cells.
- FAPP2 gene downregulation increases tumor cell sensitivity to Fas-induced apoptosis.
- PTEN knockout prostate cancer as a model for experimental immunotherapy.
- Tumor antigen precursor protein profiles of adult and pediatric brain tumors identify potential targets for immunotherapy.
- Cellular and functional characterization of immunoresistant human glioma cell clones selected with alloreactive cytotoxic T lymphocytes reveals their up-regulated synt...
- Antigenic profiling of glioma cells to generate allogeneic vaccines or dendritic cell-based therapeutics.
- Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes.
- Reduced glioma infiltration in Src-deficient mice.
- Isolation of immunoresistant human glioma cell clones after selection with alloreactive cytotoxic T lymphocytes: cytogenetic and molecular cytogenetic characterization.
- Microglia phagocytose alloreactive CTL-damaged 9L gliosarcoma cells.
- Interactions of the allogeneic effector leukemic T cell line, TALL-104, with human malignant brain tumors.
- Isolation and culture of human brain tumor cells.
- Gamma interferon transduced 9L gliosarcoma. Cytokine gene therapy and its relevance to cellular therapy with alloreactive cytotoxic T lymphocytes.
- Human alloreactive CTL interactions with gliomas and with those having upregulated HLA expression from exogenous IFN-gamma or IFN-gamma gene modification.
- Suicide gene therapy with Herpes simplex virus thymidine kinase and ganciclovir is enhanced with connexins to improve gap junctions and bystander effects.
- Effects of IFN-gamma and interleukin-1beta on major histocompatibility complex antigen and intercellular adhesion molecule-1 expression by 9L gliosarcoma: relevance to...
- Ribozyme to proliferating cell nuclear antigen to treat proliferative vitreoretinopathy.
- Purified herpes simplex virus thymidine kinase retroviral particles: III. Characterization of bystander killing mechanisms in transfected tumor cells.
- Strategies using the immune system for therapy of brain tumors.
- Chemo-immunotherapy and chemo-adoptive immunotherapy of cancer.
- Immunologic approaches to therapy for brain tumors.
- The human leukemic T-cell line, TALL-104, is cytotoxic to human malignant brain tumors and traffics through brain tissue: implications for local adoptive immunotherapy.
- Purified herpes simplex thymidine kinase retroviral particles. II. Influence of clinical parameters and bystander killing mechanisms.
- Paucity of retinoic acid receptor alpha (RAR alpha) nuclear immunostaining in gliomas and inability of retinoic acid to influence neural cell adhesion molecule (NCAM) ...
- Receptor expression, cytogenetic, and molecular analysis of six continuous human glioma cell lines.
- Establishment and characterization of a human glioblastoma multiforme cell line.
- Overexpression of a transmembrane isoform of neural cell adhesion molecule alters the invasiveness of rat CNS-1 glioma.
- Treatment of recurrent glioma with intracavitary alloreactive cytotoxic T lymphocytes and interleukin-2.
- Artificial-capillary-system development of human alloreactive cytotoxic T-lymphocytes that lyse brain tumours.
- Purified herpes simplex thymidine kinase Retrovector particles. I. In vitro characterization, in situ transduction efficiency, and histopathological analyses of gene t...
- Neural cell adhesion molecule expression in human pituitary adenomas.
- Migration of activated lymphocytes when adoptively transferred into cannulated rat brain.
- Intracranial administrations of single or multiple source allogeneic cytotoxic T lymphocytes: chronic therapy for primary brain tumors.
- A rat glioma model, CNS-1, with invasive characteristics similar to those of human gliomas: a comparison to 9L gliosarcoma.
- Adjuvant adoptive immunotherapy for pediatric recurrent brain tumors.
- Alveolar soft part sarcoma: an unusually long interval between presentation and brain metastasis.
- Systemic chemotherapy combined with local adoptive immunotherapy cures rats bearing 9L gliosarcoma.
- Characterization of a continuous human glioma cell line DBTRG-05MG: growth kinetics, karyotype, receptor expression, and tumor suppressor gene analyses.
- Allogeneic tumor-specific cytotoxic T lymphocytes.
- A 9L gliosarcoma transplantation model for studying adoptive immunotherapy into the brains of conscious rats.
- Cytotoxicity against autologous, allogeneic, and xenogeneic tumor targets by human recombinant interleukin-2-activated lymphocytes from healthy dogs and dogs with lung...
- Ultrastructural observations on the transformations of osmotically stressed and electrically pulsed red cell carriers at stages during their formation.
- Long-term follow-up of patients with recurrent malignant gliomas treated with adjuvant adoptive immunotherapy.
- Analysis of interleukin 2 and various effector cell populations in adoptive immunotherapy of 9L rat gliosarcoma: allogeneic cytotoxic T lymphocytes prevent tumor take.
- Bioactivity of electric field-pulsed human recombinant interleukin-2 and its encapsulation into erythrocyte carriers.
- Lymphokine-activated killer cells with interleukin-2: dose toxicity and localization in isolated perfused rat lungs.
- Methotrexate loading of red cell carriers by osmotic stress and electric-pulse methods: ultrastructural observations.
- Interleukin-2-activated lymphocytes from brain tumor patients. A comparison of two preparations generated in vitro.
Doctors Specialties
- Family Medicine
- Nursing (Nurse Practitioner)
Accepted Insurances
Education
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Stony Brook University School of Medicine
Hospital
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Lee Memorial Hospital
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